FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034808546> ?p ?o ?g. }

• W2034808546 endingPage "5708" @default.
• W2034808546 startingPage "5700" @default.
• W2034808546 abstract "The cell surface receptors for PRL and interleukin-2 (IL-2) are structurally distinct, but share regulatory tasks in T lymphocytes. They can stimulate proliferation and activate transcription of over-lapping sets of genes of T cells. PRL and IL-2 receptor activation are both linked to the Jak/Stat (signal transducer and activator of transcription) pathway. We investigated the ability of PRL and IL-2 to activate Stat proteins in different T cell lines. The DNA binding specificities, the reactivities toward Stat-specific antisera, and the mol wt of IL-2- and PRL-induced DNA-binding proteins in Nb2 and C196 T cell lines were investigated. A comparison with the Stat proteins induced by interferon-gamma, PRL, and IL-6 in T47D mammary tumor cells was made. We found that these parameters were indistinguishable for one of the PRL- and IL-2-induced factors. A transcription factor closely related to mammary gland factor-Stat5 is rapidly activated upon interaction of IL-2 and PRL with their respective receptors. Activation of a second protein related to Stat1 was also observed. Our results emphasize the role of PRL as a regulator of the immune response and indicate that the Stat factors mammary gland factor-Stat5 and Stat1 play a role in the regulation of gene expression during T cell development." @default.
• W2034808546 created "2016-06-24" @default.
• W2034808546 creator A5001016955 @default.
• W2034808546 creator A5014678514 @default.
• W2034808546 creator A5014910951 @default.
• W2034808546 creator A5016115013 @default.
• W2034808546 creator A5050180217 @default.
• W2034808546 creator A5071582293 @default.
• W2034808546 date "1995-12-01" @default.
• W2034808546 modified "2023-10-09" @default.
• W2034808546 title "Prolactin and interleukin-2 receptors in T lymphocytes signal through a MGF-STAT5-like transcription factor." @default.
• W2034808546 cites W11800597 @default.
• W2034808546 cites W1486018587 @default.
• W2034808546 cites W1510347472 @default.
• W2034808546 cites W1514059110 @default.
• W2034808546 cites W1515457450 @default.
• W2034808546 cites W1538909114 @default.
• W2034808546 cites W1558682805 @default.
• W2034808546 cites W1578727637 @default.
• W2034808546 cites W1669690603 @default.
• W2034808546 cites W1758311809 @default.
• W2034808546 cites W1882868104 @default.
• W2034808546 cites W1942718916 @default.
• W2034808546 cites W1951084542 @default.
• W2034808546 cites W1981799488 @default.
• W2034808546 cites W1983630074 @default.
• W2034808546 cites W1984245635 @default.
• W2034808546 cites W1997785224 @default.
• W2034808546 cites W2013444563 @default.
• W2034808546 cites W2017654948 @default.
• W2034808546 cites W2018338936 @default.
• W2034808546 cites W2029275361 @default.
• W2034808546 cites W2032264357 @default.
• W2034808546 cites W2034974668 @default.
• W2034808546 cites W2041187882 @default.
• W2034808546 cites W2051233933 @default.
• W2034808546 cites W2052172628 @default.
• W2034808546 cites W2062005942 @default.
• W2034808546 cites W2067626539 @default.
• W2034808546 cites W2086240590 @default.
• W2034808546 cites W2089523203 @default.
• W2034808546 cites W2094229090 @default.
• W2034808546 cites W2096746841 @default.
• W2034808546 cites W2109389988 @default.
• W2034808546 cites W2130982757 @default.
• W2034808546 cites W2132633540 @default.
• W2034808546 cites W2145996190 @default.
• W2034808546 cites W2165588484 @default.
• W2034808546 cites W2468960333 @default.
• W2034808546 cites W334134150 @default.
• W2034808546 cites W4553897 @default.
• W2034808546 cites W77986286 @default.
• W2034808546 doi "https://doi.org/10.1210/endo.136.12.7588326" @default.
• W2034808546 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7588326" @default.
• W2034808546 hasPublicationYear "1995" @default.
• W2034808546 type Work @default.
• W2034808546 sameAs 2034808546 @default.
• W2034808546 citedByCount "56" @default.
• W2034808546 countsByYear W20348085462015 @default.
• W2034808546 countsByYear W20348085462018 @default.
• W2034808546 crossrefType "journal-article" @default.
• W2034808546 hasAuthorship W2034808546A5001016955 @default.
• W2034808546 hasAuthorship W2034808546A5014678514 @default.
• W2034808546 hasAuthorship W2034808546A5014910951 @default.
• W2034808546 hasAuthorship W2034808546A5016115013 @default.
• W2034808546 hasAuthorship W2034808546A5050180217 @default.
• W2034808546 hasAuthorship W2034808546A5071582293 @default.
• W2034808546 hasBestOaLocation W20348085462 @default.
• W2034808546 hasConcept C104317684 @default.
• W2034808546 hasConcept C126322002 @default.
• W2034808546 hasConcept C134018914 @default.
• W2034808546 hasConcept C153911025 @default.
• W2034808546 hasConcept C170493617 @default.
• W2034808546 hasConcept C171958077 @default.
• W2034808546 hasConcept C2777003663 @default.
• W2034808546 hasConcept C2778277574 @default.
• W2034808546 hasConcept C2778923194 @default.
• W2034808546 hasConcept C2779064019 @default.
• W2034808546 hasConcept C2779391668 @default.
• W2034808546 hasConcept C55493867 @default.
• W2034808546 hasConcept C62478195 @default.
• W2034808546 hasConcept C65439459 @default.
• W2034808546 hasConcept C71315377 @default.
• W2034808546 hasConcept C71924100 @default.
• W2034808546 hasConcept C86339819 @default.
• W2034808546 hasConcept C86803240 @default.
• W2034808546 hasConcept C95444343 @default.
• W2034808546 hasConceptScore W2034808546C104317684 @default.
• W2034808546 hasConceptScore W2034808546C126322002 @default.
• W2034808546 hasConceptScore W2034808546C134018914 @default.
• W2034808546 hasConceptScore W2034808546C153911025 @default.
• W2034808546 hasConceptScore W2034808546C170493617 @default.
• W2034808546 hasConceptScore W2034808546C171958077 @default.
• W2034808546 hasConceptScore W2034808546C2777003663 @default.
• W2034808546 hasConceptScore W2034808546C2778277574 @default.
• W2034808546 hasConceptScore W2034808546C2778923194 @default.
• W2034808546 hasConceptScore W2034808546C2779064019 @default.
• W2034808546 hasConceptScore W2034808546C2779391668 @default.

• next