FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034839917> ?p ?o ?g. }

• W2034839917 endingPage "48" @default.
• W2034839917 startingPage "43" @default.
• W2034839917 abstract "Abstract Objective. Synovial fluid lymphocytes from patients with rheumatoid arthritis and with other forms of inflammatory synovitis demonstrate enhanced proliferative responses to Mycobacterium tuberculosis antigens, in particular, the 65‐kd heat‐shock protein. There is a high degree of homology between the human and the mycobacterial 60‐kd family of heat‐shock proteins. These studies were performed to determine if the enhanced response to the mycobacterial 65‐kd heat‐shock protein was due to cross‐reactivity of an immune response generated against the human homolog. Methods. These studies were performed by in vitro culture of isolated synovial fluid mononuclear cells with crude and purified antigens. Results. The synovial fluid lymphocytes of a majority of patients with rheumatoid arthritis recognized the mycobacterial 65‐kd heat‐shock protein, as evidenced by T cell proliferation. In contrast, only 18% of all samples tested responded to a highly purified recombinant human 60‐kd heat‐shock protein. With only one exception, proliferative responses to the mycobacterial antigen were stronger than those to the human homolog. The proliferative responses generated against mycobacterial 65‐kd heat‐shock proteins from different sources were highly correlated. Conclusion. The findings suggest that the enhanced proliferative response to the mycobacterial 65‐kd heat‐shock protein noted in most patients with rheumatoid arthritis and other forms of inflammatory synovitis is not due to cross‐reactivity of an immune response directed against the human heat‐shock protein." @default.
• W2034839917 created "2016-06-24" @default.
• W2034839917 creator A5016758814 @default.
• W2034839917 creator A5062155931 @default.
• W2034839917 creator A5085988586 @default.
• W2034839917 date "1992-01-01" @default.
• W2034839917 modified "2023-10-03" @default.
• W2034839917 title "Activation of Synovial Fluid T Lymphocytes by 60‐Kd Heat‐Shock Proteins in Patients with Inflammatory synovitis" @default.
• W2034839917 cites W1488021735 @default.
• W2034839917 cites W189209391 @default.
• W2034839917 cites W1920925630 @default.
• W2034839917 cites W1935621669 @default.
• W2034839917 cites W1942122996 @default.
• W2034839917 cites W1951673049 @default.
• W2034839917 cites W1954689247 @default.
• W2034839917 cites W1966588987 @default.
• W2034839917 cites W1984307342 @default.
• W2034839917 cites W1987492973 @default.
• W2034839917 cites W2008400210 @default.
• W2034839917 cites W2019564259 @default.
• W2034839917 cites W2046690548 @default.
• W2034839917 cites W2080308097 @default.
• W2034839917 cites W2084001516 @default.
• W2034839917 cites W2085858142 @default.
• W2034839917 cites W2096383393 @default.
• W2034839917 cites W2113858637 @default.
• W2034839917 cites W2114155835 @default.
• W2034839917 cites W2130863508 @default.
• W2034839917 cites W2132623931 @default.
• W2034839917 cites W2141882809 @default.
• W2034839917 cites W2152348310 @default.
• W2034839917 cites W2155934529 @default.
• W2034839917 cites W2158332082 @default.
• W2034839917 cites W2164959530 @default.
• W2034839917 doi "https://doi.org/10.1002/art.1780350107" @default.
• W2034839917 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1731814" @default.
• W2034839917 hasPublicationYear "1992" @default.
• W2034839917 type Work @default.
• W2034839917 sameAs 2034839917 @default.
• W2034839917 citedByCount "47" @default.
• W2034839917 countsByYear W20348399172013 @default.
• W2034839917 crossrefType "journal-article" @default.
• W2034839917 hasAuthorship W2034839917A5016758814 @default.
• W2034839917 hasAuthorship W2034839917A5062155931 @default.
• W2034839917 hasAuthorship W2034839917A5085988586 @default.
• W2034839917 hasConcept C104317684 @default.
• W2034839917 hasConcept C137061746 @default.
• W2034839917 hasConcept C137984847 @default.
• W2034839917 hasConcept C142724271 @default.
• W2034839917 hasConcept C147483822 @default.
• W2034839917 hasConcept C202751555 @default.
• W2034839917 hasConcept C203014093 @default.
• W2034839917 hasConcept C204787440 @default.
• W2034839917 hasConcept C205260736 @default.
• W2034839917 hasConcept C2776164576 @default.
• W2034839917 hasConcept C2776268809 @default.
• W2034839917 hasConcept C2777077863 @default.
• W2034839917 hasConcept C2777575956 @default.
• W2034839917 hasConcept C2779244835 @default.
• W2034839917 hasConcept C55493867 @default.
• W2034839917 hasConcept C68991219 @default.
• W2034839917 hasConcept C71924100 @default.
• W2034839917 hasConcept C86803240 @default.
• W2034839917 hasConcept C8891405 @default.
• W2034839917 hasConceptScore W2034839917C104317684 @default.
• W2034839917 hasConceptScore W2034839917C137061746 @default.
• W2034839917 hasConceptScore W2034839917C137984847 @default.
• W2034839917 hasConceptScore W2034839917C142724271 @default.
• W2034839917 hasConceptScore W2034839917C147483822 @default.
• W2034839917 hasConceptScore W2034839917C202751555 @default.
• W2034839917 hasConceptScore W2034839917C203014093 @default.
• W2034839917 hasConceptScore W2034839917C204787440 @default.
• W2034839917 hasConceptScore W2034839917C205260736 @default.
• W2034839917 hasConceptScore W2034839917C2776164576 @default.
• W2034839917 hasConceptScore W2034839917C2776268809 @default.
• W2034839917 hasConceptScore W2034839917C2777077863 @default.
• W2034839917 hasConceptScore W2034839917C2777575956 @default.
• W2034839917 hasConceptScore W2034839917C2779244835 @default.
• W2034839917 hasConceptScore W2034839917C55493867 @default.
• W2034839917 hasConceptScore W2034839917C68991219 @default.
• W2034839917 hasConceptScore W2034839917C71924100 @default.
• W2034839917 hasConceptScore W2034839917C86803240 @default.
• W2034839917 hasConceptScore W2034839917C8891405 @default.
• W2034839917 hasIssue "1" @default.
• W2034839917 hasLocation W20348399171 @default.
• W2034839917 hasLocation W20348399172 @default.
• W2034839917 hasOpenAccess W2034839917 @default.
• W2034839917 hasPrimaryLocation W20348399171 @default.
• W2034839917 hasRelatedWork W1991708320 @default.
• W2034839917 hasRelatedWork W2034822193 @default.
• W2034839917 hasRelatedWork W2034839917 @default.
• W2034839917 hasRelatedWork W2051416328 @default.
• W2034839917 hasRelatedWork W2061747410 @default.
• W2034839917 hasRelatedWork W2104646232 @default.
• W2034839917 hasRelatedWork W2138830441 @default.
• W2034839917 hasRelatedWork W2587191489 @default.
• W2034839917 hasRelatedWork W3016436836 @default.
• W2034839917 hasRelatedWork W30823485 @default.

• next