Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034842435> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2034842435 endingPage "1017" @default.
- W2034842435 startingPage "1011" @default.
- W2034842435 abstract "(+/-)-2-(5,6-Dimethoxy-1,2,3,4-tetrahydro-1-naphthyl)imidazoline has been resolved into its (+) and (-) enantiomers, and the absolute configuration was established by single-crystal X-ray diffraction studies. The more active isomer has been assigned the R absolute configuration. Cleavage of the respective (+)- and (-)-dimethyl ethers with boron tribromide provided the corresponding (+)- and (-)-2-(5,6-dihydroxy-1,2,3,4-tetrahydro-1-naphthl)imidazoline hydrobromides and these were pharmacologically characterized. In various preparations, the R enantiomer has been shown to be an extremely potent alpha agonist with preferential activity at the alpha 2-adrenergic receptor." @default.
- W2034842435 created "2016-06-24" @default.
- W2034842435 creator A5013578316 @default.
- W2034842435 creator A5027365700 @default.
- W2034842435 creator A5035099602 @default.
- W2034842435 creator A5076141903 @default.
- W2034842435 creator A5082377700 @default.
- W2034842435 creator A5083071334 @default.
- W2034842435 date "1987-06-01" @default.
- W2034842435 modified "2023-09-26" @default.
- W2034842435 title "Conformationally defined adrenergic agents. 5. Resolution, absolute configuration, and pharmacological characterization of the enantiomers of 2-(5,6-dihydroxy-1,2,3,4-tetrahydro-1-naphthyl)imidazoline: a potent agonist at .alpha.-adrenoceptors" @default.
- W2034842435 doi "https://doi.org/10.1021/jm00389a009" @default.
- W2034842435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2884313" @default.
- W2034842435 hasPublicationYear "1987" @default.
- W2034842435 type Work @default.
- W2034842435 sameAs 2034842435 @default.
- W2034842435 citedByCount "10" @default.
- W2034842435 countsByYear W20348424352021 @default.
- W2034842435 crossrefType "journal-article" @default.
- W2034842435 hasAuthorship W2034842435A5013578316 @default.
- W2034842435 hasAuthorship W2034842435A5027365700 @default.
- W2034842435 hasAuthorship W2034842435A5035099602 @default.
- W2034842435 hasAuthorship W2034842435A5076141903 @default.
- W2034842435 hasAuthorship W2034842435A5082377700 @default.
- W2034842435 hasAuthorship W2034842435A5083071334 @default.
- W2034842435 hasConcept C123605464 @default.
- W2034842435 hasConcept C159110408 @default.
- W2034842435 hasConcept C170493617 @default.
- W2034842435 hasConcept C185592680 @default.
- W2034842435 hasConcept C25170562 @default.
- W2034842435 hasConcept C2775944032 @default.
- W2034842435 hasConcept C2778938600 @default.
- W2034842435 hasConcept C486523 @default.
- W2034842435 hasConcept C49453240 @default.
- W2034842435 hasConcept C55493867 @default.
- W2034842435 hasConcept C64943373 @default.
- W2034842435 hasConcept C71240020 @default.
- W2034842435 hasConcept C71924100 @default.
- W2034842435 hasConcept C98274493 @default.
- W2034842435 hasConceptScore W2034842435C123605464 @default.
- W2034842435 hasConceptScore W2034842435C159110408 @default.
- W2034842435 hasConceptScore W2034842435C170493617 @default.
- W2034842435 hasConceptScore W2034842435C185592680 @default.
- W2034842435 hasConceptScore W2034842435C25170562 @default.
- W2034842435 hasConceptScore W2034842435C2775944032 @default.
- W2034842435 hasConceptScore W2034842435C2778938600 @default.
- W2034842435 hasConceptScore W2034842435C486523 @default.
- W2034842435 hasConceptScore W2034842435C49453240 @default.
- W2034842435 hasConceptScore W2034842435C55493867 @default.
- W2034842435 hasConceptScore W2034842435C64943373 @default.
- W2034842435 hasConceptScore W2034842435C71240020 @default.
- W2034842435 hasConceptScore W2034842435C71924100 @default.
- W2034842435 hasConceptScore W2034842435C98274493 @default.
- W2034842435 hasIssue "6" @default.
- W2034842435 hasLocation W20348424351 @default.
- W2034842435 hasLocation W20348424352 @default.
- W2034842435 hasOpenAccess W2034842435 @default.
- W2034842435 hasPrimaryLocation W20348424351 @default.
- W2034842435 hasRelatedWork W1994826601 @default.
- W2034842435 hasRelatedWork W2004325083 @default.
- W2034842435 hasRelatedWork W2030467887 @default.
- W2034842435 hasRelatedWork W2034842435 @default.
- W2034842435 hasRelatedWork W2048525790 @default.
- W2034842435 hasRelatedWork W2088208576 @default.
- W2034842435 hasRelatedWork W2766307063 @default.
- W2034842435 hasRelatedWork W2949467816 @default.
- W2034842435 hasRelatedWork W2951136615 @default.
- W2034842435 hasRelatedWork W2952897947 @default.
- W2034842435 hasVolume "30" @default.
- W2034842435 isParatext "false" @default.
- W2034842435 isRetracted "false" @default.
- W2034842435 magId "2034842435" @default.
- W2034842435 workType "article" @default.