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• W2034852042 endingPage "172" @default.
• W2034852042 startingPage "157" @default.
• W2034852042 abstract "The uptake of GABA, glycine, glutamic acid, aspartic, l-DOPA, dopamine and histamine into the rabbit retina in vivo and in vitro was studied autoradiographically. GABA and glycine accumulated in cells that had in the main the position and spread of amacrine cells and also in some ganglion cells. Radioactivity appeared in Mu¨ller cells and retinal pigment cells after exposure of the retina to aspartic or glutamic acid in vivo. After exposure to histamine in vivo, radioactivity appeared in the retinal pigment cells and diffusely in the retina. l-DOPA and dopamine were taken up into cells with the position of the adrenergic retinal neurons. The experiments demonstrate that in central nervous tissue such as the retina, certain classes of cells preferentially accumulate glycine or GABA, presumably into two different sets of cells. For several reasons, it is less probable that ganglion cells operate with either glycine or GABA as neurotransmitter; the results thus suggest that the preferential uptake of either substance into a cell is not necessarily a sign of its being a neurotransmitter in the particular cell. However, reasons are given for presuming GABA to be the neurotransmitter of certain amacrine cells, and the results also suggest that a similar role for glycine is worthy of further consideration." @default.
• W2034852042 created "2016-06-24" @default.
• W2034852042 creator A5029984601 @default.
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• W2034852042 date "1971-10-01" @default.
• W2034852042 modified "2023-10-09" @default.
• W2034852042 title "Autoradiography of some suspected neurotransmitter substances: GABA glycine, glutamic acid, histamine, dopamine, and pl-dopa" @default.
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• W2034852042 doi "https://doi.org/10.1016/0006-8993(71)90314-3" @default.
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