FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034854588> ?p ?o ?g. }

• W2034854588 abstract "The protein kinases includes many oncogenes and growth-factor receptors, as well as genes that are involved in cell cycle regulation. EphB4 receptors are a subfamily of receptor tyrosine kinases that are activated by ephrin-B2 ligands and are thought to play an important role in the development and oncogenesis of various tissues. However, very little experimental evidence exists to support this hypothesis. To elucidate the involvement of EphB4 and ephrin-B2 in endometrial carcinogenesis, we used fluorescent immunohistochemistry to analyze serial frozen sections of 20 endometrial carcinomas and 20 normal endometria for EphB4 and ephrin-B2 protein expression. We analyzed the relationship between the patient's characteristics and the percentages of EphB4- and ephrin-B2-stained cells. EphB4 expression was significantly associated with histological grade (p < 0.001) and certain clinical stages. Ephrin-B2 Expression was significantly associated with the presence of invasion to > 1/2 myometrium (p = 0.002). Our results demonstrate that increased EphB4 and ephrin-B2 expression may reflect or induce in endometrial carcinomas increased potential for growth and tumorigenicity. Furthermore, these results suggest that EphB4 receptor kinase may modulate the biological behavior of endometrial carcinomas through autocrine and/or paracrine activation, which is caused by ephrin-B2 ligands that are expressed in the same or neighbouring cells by immunohistochemistry." @default.
• W2034854588 created "2016-06-24" @default.
• W2034854588 creator A5030377560 @default.
• W2034854588 creator A5054483766 @default.
• W2034854588 creator A5059587982 @default.
• W2034854588 creator A5071775552 @default.
• W2034854588 creator A5086185811 @default.
• W2034854588 date "2001-05-01" @default.
• W2034854588 modified "2023-10-16" @default.
• W2034854588 title "Expression of receptor tyrosine kinase EphB4 and its ligand ephrin-B2 is associated with malignant potential in endometrial cancer" @default.
• W2034854588 doi "https://doi.org/10.3892/or.8.3.567" @default.
• W2034854588 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11295082" @default.
• W2034854588 hasPublicationYear "2001" @default.
• W2034854588 type Work @default.
• W2034854588 sameAs 2034854588 @default.
• W2034854588 citedByCount "25" @default.
• W2034854588 countsByYear W20348545882015 @default.
• W2034854588 countsByYear W20348545882016 @default.
• W2034854588 countsByYear W20348545882017 @default.
• W2034854588 countsByYear W20348545882019 @default.
• W2034854588 countsByYear W20348545882021 @default.
• W2034854588 countsByYear W20348545882022 @default.
• W2034854588 crossrefType "journal-article" @default.
• W2034854588 hasAuthorship W2034854588A5030377560 @default.
• W2034854588 hasAuthorship W2034854588A5054483766 @default.
• W2034854588 hasAuthorship W2034854588A5059587982 @default.
• W2034854588 hasAuthorship W2034854588A5071775552 @default.
• W2034854588 hasAuthorship W2034854588A5086185811 @default.
• W2034854588 hasConcept C101544691 @default.
• W2034854588 hasConcept C121608353 @default.
• W2034854588 hasConcept C128240485 @default.
• W2034854588 hasConcept C134018914 @default.
• W2034854588 hasConcept C170286479 @default.
• W2034854588 hasConcept C170493617 @default.
• W2034854588 hasConcept C184235292 @default.
• W2034854588 hasConcept C203014093 @default.
• W2034854588 hasConcept C204232928 @default.
• W2034854588 hasConcept C2777088508 @default.
• W2034854588 hasConcept C2778164554 @default.
• W2034854588 hasConcept C2779066055 @default.
• W2034854588 hasConcept C2779742232 @default.
• W2034854588 hasConcept C2781018059 @default.
• W2034854588 hasConcept C29537977 @default.
• W2034854588 hasConcept C42362537 @default.
• W2034854588 hasConcept C502942594 @default.
• W2034854588 hasConcept C54355233 @default.
• W2034854588 hasConcept C55493867 @default.
• W2034854588 hasConcept C555283112 @default.
• W2034854588 hasConcept C62478195 @default.
• W2034854588 hasConcept C7876069 @default.
• W2034854588 hasConcept C86803240 @default.
• W2034854588 hasConcept C95444343 @default.
• W2034854588 hasConceptScore W2034854588C101544691 @default.
• W2034854588 hasConceptScore W2034854588C121608353 @default.
• W2034854588 hasConceptScore W2034854588C128240485 @default.
• W2034854588 hasConceptScore W2034854588C134018914 @default.
• W2034854588 hasConceptScore W2034854588C170286479 @default.
• W2034854588 hasConceptScore W2034854588C170493617 @default.
• W2034854588 hasConceptScore W2034854588C184235292 @default.
• W2034854588 hasConceptScore W2034854588C203014093 @default.
• W2034854588 hasConceptScore W2034854588C204232928 @default.
• W2034854588 hasConceptScore W2034854588C2777088508 @default.
• W2034854588 hasConceptScore W2034854588C2778164554 @default.
• W2034854588 hasConceptScore W2034854588C2779066055 @default.
• W2034854588 hasConceptScore W2034854588C2779742232 @default.
• W2034854588 hasConceptScore W2034854588C2781018059 @default.
• W2034854588 hasConceptScore W2034854588C29537977 @default.
• W2034854588 hasConceptScore W2034854588C42362537 @default.
• W2034854588 hasConceptScore W2034854588C502942594 @default.
• W2034854588 hasConceptScore W2034854588C54355233 @default.
• W2034854588 hasConceptScore W2034854588C55493867 @default.
• W2034854588 hasConceptScore W2034854588C555283112 @default.
• W2034854588 hasConceptScore W2034854588C62478195 @default.
• W2034854588 hasConceptScore W2034854588C7876069 @default.
• W2034854588 hasConceptScore W2034854588C86803240 @default.
• W2034854588 hasConceptScore W2034854588C95444343 @default.
• W2034854588 hasLocation W20348545881 @default.
• W2034854588 hasLocation W20348545882 @default.
• W2034854588 hasOpenAccess W2034854588 @default.
• W2034854588 hasPrimaryLocation W20348545881 @default.
• W2034854588 hasRelatedWork W1967720639 @default.
• W2034854588 hasRelatedWork W1972486937 @default.
• W2034854588 hasRelatedWork W1980129984 @default.
• W2034854588 hasRelatedWork W1987263161 @default.
• W2034854588 hasRelatedWork W1990027846 @default.
• W2034854588 hasRelatedWork W2000552200 @default.
• W2034854588 hasRelatedWork W2001879388 @default.
• W2034854588 hasRelatedWork W2023735985 @default.
• W2034854588 hasRelatedWork W2035595755 @default.
• W2034854588 hasRelatedWork W2042482088 @default.
• W2034854588 hasRelatedWork W2043508733 @default.
• W2034854588 hasRelatedWork W2047694154 @default.
• W2034854588 hasRelatedWork W2050906899 @default.
• W2034854588 hasRelatedWork W2088346679 @default.
• W2034854588 hasRelatedWork W2093842873 @default.
• W2034854588 hasRelatedWork W2122400343 @default.
• W2034854588 hasRelatedWork W2125533727 @default.
• W2034854588 hasRelatedWork W2144205331 @default.
• W2034854588 hasRelatedWork W2146363635 @default.
• W2034854588 hasRelatedWork W2162544707 @default.

• next