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- W2034862875 abstract "Following the initial success of imatinib as frontline therapy for chronic myeloid leukemia (CML), several second-generation therapeutics have been developed with increased potency and the ability to inhibit the majority of imatinib-resistant mutations. Here, we review the current knowledge about the target specificity of the two new inhibitors nilotinib and dasatinib in comparison to imatinib, including the recent large-scale chemical proteomics screens." @default.
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- W2034862875 date "2008-01-01" @default.
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- W2034862875 title "Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib" @default.
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- W2034862875 doi "https://doi.org/10.1080/10428190801896103" @default.
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