Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034870053> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2034870053 endingPage "206" @default.
- W2034870053 startingPage "199" @default.
- W2034870053 abstract "Trimethylsilylation of target substances in a mixture of N-methyl-N-trimethylsilyltrifluoroacetamide (MSTFA), ammonium iodide and ethanethiol is frequently applied for the application of gas chromatography-mass spectrometry (GC-MS) in steroid analysis. However, artifacts were formed when using this mixture to silylate the steroids androsterone and etiocholanolone obtained from a urine matrix. The artifacts were identified as ethyl thio-containing products of the respective trimethylsilyl derivatives. The conversion of the studied products increased slowly as a function of time, was dependent on the presence of the urine matrix and was significantly accelerated by adding diethyl disulfide to the reagent before incubation. Also ethyl thio-incorporation into testosterone and epitestosterone was established. A mechanism for ethyl thio-incorporation is proposed. The conversion achieved after 120-h sample storage at room temperature was insufficient to significantly influence the analysis of androsterone and etiocholanolone under the studied conditions. However, the results provide fundamental insight into the mechanism of silylation and the occurring side-reactions. Moreover, when investigating the formation of new metabolites, the ethyl thio-incorporation can lead to misinterpretation." @default.
- W2034870053 created "2016-06-24" @default.
- W2034870053 creator A5022161483 @default.
- W2034870053 creator A5022956205 @default.
- W2034870053 creator A5028472129 @default.
- W2034870053 creator A5029258716 @default.
- W2034870053 creator A5041368706 @default.
- W2034870053 creator A5046189771 @default.
- W2034870053 creator A5055462779 @default.
- W2034870053 creator A5063067710 @default.
- W2034870053 date "2002-04-01" @default.
- W2034870053 modified "2023-09-27" @default.
- W2034870053 title "Artifact formation due to ethyl thio-incorporation into silylated steroid structures as determined in doping analysis" @default.
- W2034870053 cites W1496215803 @default.
- W2034870053 cites W2004352413 @default.
- W2034870053 cites W2093390442 @default.
- W2034870053 cites W2095843048 @default.
- W2034870053 doi "https://doi.org/10.1016/s0021-9673(02)00177-2" @default.
- W2034870053 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12058904" @default.
- W2034870053 hasPublicationYear "2002" @default.
- W2034870053 type Work @default.
- W2034870053 sameAs 2034870053 @default.
- W2034870053 citedByCount "16" @default.
- W2034870053 countsByYear W20348700532015 @default.
- W2034870053 countsByYear W20348700532019 @default.
- W2034870053 crossrefType "journal-article" @default.
- W2034870053 hasAuthorship W2034870053A5022161483 @default.
- W2034870053 hasAuthorship W2034870053A5022956205 @default.
- W2034870053 hasAuthorship W2034870053A5028472129 @default.
- W2034870053 hasAuthorship W2034870053A5029258716 @default.
- W2034870053 hasAuthorship W2034870053A5041368706 @default.
- W2034870053 hasAuthorship W2034870053A5046189771 @default.
- W2034870053 hasAuthorship W2034870053A5055462779 @default.
- W2034870053 hasAuthorship W2034870053A5063067710 @default.
- W2034870053 hasBestOaLocation W20348700532 @default.
- W2034870053 hasConcept C161790260 @default.
- W2034870053 hasConcept C162356407 @default.
- W2034870053 hasConcept C178790620 @default.
- W2034870053 hasConcept C179104552 @default.
- W2034870053 hasConcept C185592680 @default.
- W2034870053 hasConcept C205345274 @default.
- W2034870053 hasConcept C2777344897 @default.
- W2034870053 hasConcept C2779257513 @default.
- W2034870053 hasConcept C2779341496 @default.
- W2034870053 hasConcept C2779746161 @default.
- W2034870053 hasConcept C2780749918 @default.
- W2034870053 hasConcept C2780902042 @default.
- W2034870053 hasConcept C2781253882 @default.
- W2034870053 hasConcept C43617362 @default.
- W2034870053 hasConcept C5304478 @default.
- W2034870053 hasConcept C55493867 @default.
- W2034870053 hasConcept C71315377 @default.
- W2034870053 hasConceptScore W2034870053C161790260 @default.
- W2034870053 hasConceptScore W2034870053C162356407 @default.
- W2034870053 hasConceptScore W2034870053C178790620 @default.
- W2034870053 hasConceptScore W2034870053C179104552 @default.
- W2034870053 hasConceptScore W2034870053C185592680 @default.
- W2034870053 hasConceptScore W2034870053C205345274 @default.
- W2034870053 hasConceptScore W2034870053C2777344897 @default.
- W2034870053 hasConceptScore W2034870053C2779257513 @default.
- W2034870053 hasConceptScore W2034870053C2779341496 @default.
- W2034870053 hasConceptScore W2034870053C2779746161 @default.
- W2034870053 hasConceptScore W2034870053C2780749918 @default.
- W2034870053 hasConceptScore W2034870053C2780902042 @default.
- W2034870053 hasConceptScore W2034870053C2781253882 @default.
- W2034870053 hasConceptScore W2034870053C43617362 @default.
- W2034870053 hasConceptScore W2034870053C5304478 @default.
- W2034870053 hasConceptScore W2034870053C55493867 @default.
- W2034870053 hasConceptScore W2034870053C71315377 @default.
- W2034870053 hasIssue "1-2" @default.
- W2034870053 hasLocation W20348700531 @default.
- W2034870053 hasLocation W20348700532 @default.
- W2034870053 hasLocation W20348700533 @default.
- W2034870053 hasOpenAccess W2034870053 @default.
- W2034870053 hasPrimaryLocation W20348700531 @default.
- W2034870053 hasRelatedWork W2034870053 @default.
- W2034870053 hasRelatedWork W2054762610 @default.
- W2034870053 hasRelatedWork W2063085240 @default.
- W2034870053 hasRelatedWork W2082492115 @default.
- W2034870053 hasRelatedWork W2091500539 @default.
- W2034870053 hasRelatedWork W2114810117 @default.
- W2034870053 hasRelatedWork W2115775726 @default.
- W2034870053 hasRelatedWork W2181958518 @default.
- W2034870053 hasRelatedWork W2349181306 @default.
- W2034870053 hasRelatedWork W3197679186 @default.
- W2034870053 hasVolume "954" @default.
- W2034870053 isParatext "false" @default.
- W2034870053 isRetracted "false" @default.
- W2034870053 magId "2034870053" @default.
- W2034870053 workType "article" @default.