Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034881918> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2034881918 endingPage "12021" @default.
- W2034881918 startingPage "12013" @default.
- W2034881918 abstract "The Msx-1 homeodomain protein plays a crucial role in craniofacial, limb, and nervous system development. Homeodomain DNA-binding domains are comprised of 60 amino acids that show a high degree of evolutionary conservation. We have determined the structure of the Msx-1 homeodomain complexed to DNA at 2.2 A resolution. The structure has an unusually well-ordered N-terminal arm with a unique trajectory across the minor groove of the DNA. DNA specificity conferred by bases flanking the core TAAT sequence is explained by well ordered water-mediated interactions at Q50. Most interactions seen at the TAAT sequence are typical of the interactions seen in other homeodomain structures. Comparison of the Msx-1-HD structure to all other high resolution HD-DNA complex structures indicate a remarkably well-conserved sphere of hydration between the DNA and protein in these complexes." @default.
- W2034881918 created "2016-06-24" @default.
- W2034881918 creator A5008371614 @default.
- W2034881918 creator A5033587895 @default.
- W2034881918 creator A5051291962 @default.
- W2034881918 date "2001-09-14" @default.
- W2034881918 modified "2023-09-26" @default.
- W2034881918 title "Crystal Structure of the Msx-1 Homeodomain/DNA Complex<sup>,</sup>" @default.
- W2034881918 cites W1836912647 @default.
- W2034881918 cites W1925430508 @default.
- W2034881918 cites W1965026326 @default.
- W2034881918 cites W1967194316 @default.
- W2034881918 cites W2000145984 @default.
- W2034881918 cites W2004689349 @default.
- W2034881918 cites W2008698435 @default.
- W2034881918 cites W2012879549 @default.
- W2034881918 cites W2047713072 @default.
- W2034881918 cites W2049521571 @default.
- W2034881918 cites W2050843661 @default.
- W2034881918 cites W2051355046 @default.
- W2034881918 cites W2055573396 @default.
- W2034881918 cites W2068494490 @default.
- W2034881918 cites W2073978055 @default.
- W2034881918 cites W2077811970 @default.
- W2034881918 cites W2080476827 @default.
- W2034881918 cites W2084834955 @default.
- W2034881918 cites W2086368648 @default.
- W2034881918 cites W2090530814 @default.
- W2034881918 cites W2105207670 @default.
- W2034881918 cites W2126223002 @default.
- W2034881918 doi "https://doi.org/10.1021/bi0108148" @default.
- W2034881918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11580277" @default.
- W2034881918 hasPublicationYear "2001" @default.
- W2034881918 type Work @default.
- W2034881918 sameAs 2034881918 @default.
- W2034881918 citedByCount "57" @default.
- W2034881918 countsByYear W20348819182012 @default.
- W2034881918 countsByYear W20348819182013 @default.
- W2034881918 countsByYear W20348819182014 @default.
- W2034881918 countsByYear W20348819182015 @default.
- W2034881918 countsByYear W20348819182016 @default.
- W2034881918 countsByYear W20348819182017 @default.
- W2034881918 countsByYear W20348819182018 @default.
- W2034881918 countsByYear W20348819182019 @default.
- W2034881918 countsByYear W20348819182020 @default.
- W2034881918 countsByYear W20348819182021 @default.
- W2034881918 countsByYear W20348819182023 @default.
- W2034881918 crossrefType "journal-article" @default.
- W2034881918 hasAuthorship W2034881918A5008371614 @default.
- W2034881918 hasAuthorship W2034881918A5033587895 @default.
- W2034881918 hasAuthorship W2034881918A5051291962 @default.
- W2034881918 hasConcept C104317684 @default.
- W2034881918 hasConcept C121587040 @default.
- W2034881918 hasConcept C185592680 @default.
- W2034881918 hasConcept C54355233 @default.
- W2034881918 hasConcept C552990157 @default.
- W2034881918 hasConcept C8010536 @default.
- W2034881918 hasConcept C86339819 @default.
- W2034881918 hasConcept C86803240 @default.
- W2034881918 hasConceptScore W2034881918C104317684 @default.
- W2034881918 hasConceptScore W2034881918C121587040 @default.
- W2034881918 hasConceptScore W2034881918C185592680 @default.
- W2034881918 hasConceptScore W2034881918C54355233 @default.
- W2034881918 hasConceptScore W2034881918C552990157 @default.
- W2034881918 hasConceptScore W2034881918C8010536 @default.
- W2034881918 hasConceptScore W2034881918C86339819 @default.
- W2034881918 hasConceptScore W2034881918C86803240 @default.
- W2034881918 hasIssue "40" @default.
- W2034881918 hasLocation W20348819181 @default.
- W2034881918 hasLocation W20348819182 @default.
- W2034881918 hasOpenAccess W2034881918 @default.
- W2034881918 hasPrimaryLocation W20348819181 @default.
- W2034881918 hasRelatedWork W157987876 @default.
- W2034881918 hasRelatedWork W1876243977 @default.
- W2034881918 hasRelatedWork W1886625688 @default.
- W2034881918 hasRelatedWork W1966967813 @default.
- W2034881918 hasRelatedWork W1970327593 @default.
- W2034881918 hasRelatedWork W2077497255 @default.
- W2034881918 hasRelatedWork W2136955853 @default.
- W2034881918 hasRelatedWork W2526708792 @default.
- W2034881918 hasRelatedWork W4213205422 @default.
- W2034881918 hasRelatedWork W4232945047 @default.
- W2034881918 hasVolume "40" @default.
- W2034881918 isParatext "false" @default.
- W2034881918 isRetracted "false" @default.
- W2034881918 magId "2034881918" @default.
- W2034881918 workType "article" @default.