Matches in SemOpenAlex for { <https://semopenalex.org/work/W20348850> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W20348850 endingPage "53" @default.
- W20348850 startingPage "449" @default.
- W20348850 abstract "The effect of a number of drugs commonly used to treat the more severe exacerbations of the autoimmune disease systemic lupus erythematosus (SLE) in humans has been investigated in the murine chronic graft-versus-host (GVH) induced model of lupus. This was undertaken in order to determine the value of this model for the investigation of immunomodulant drugs, with particular regard to the reproducibility of disease induction and methods of monitoring disease progression. The drugs were azathioprine, cyclophosphamide, cyclosporin A and dexamethasone. All of these, except for azathioprine, reduced disease severity, assessed as the development of lupus nephritis. Anti-ssDNA autoantibodies were also reduced in titre in the dexamethasone-treated group. Overall, these findings, combined with the reproducible induction of disease seen in this model, support the use of chronic GVH disease as a model for SLE and show that the induced disease can be ameliorated by drugs effective in the treatment of SLE in humans." @default.
- W20348850 created "2016-06-24" @default.
- W20348850 creator A5042225434 @default.
- W20348850 creator A5046936244 @default.
- W20348850 creator A5090250975 @default.
- W20348850 date "1989-12-01" @default.
- W20348850 modified "2023-09-27" @default.
- W20348850 title "Murine chronic graft-versus-host disease as a model of systemic lupus erythematosus: effect of immunosuppressive drugs on disease development." @default.
- W20348850 cites W1448288193 @default.
- W20348850 cites W1494496956 @default.
- W20348850 cites W1589732475 @default.
- W20348850 cites W1965355993 @default.
- W20348850 cites W2007783831 @default.
- W20348850 cites W2015931163 @default.
- W20348850 cites W2035093315 @default.
- W20348850 cites W2227157639 @default.
- W20348850 cites W2407818189 @default.
- W20348850 cites W2422555475 @default.
- W20348850 cites W2996603844 @default.
- W20348850 cites W327112295 @default.
- W20348850 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1534813" @default.
- W20348850 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2612055" @default.
- W20348850 hasPublicationYear "1989" @default.
- W20348850 type Work @default.
- W20348850 sameAs 20348850 @default.
- W20348850 citedByCount "5" @default.
- W20348850 countsByYear W203488502015 @default.
- W20348850 countsByYear W203488502022 @default.
- W20348850 crossrefType "journal-article" @default.
- W20348850 hasAuthorship W20348850A5042225434 @default.
- W20348850 hasAuthorship W20348850A5046936244 @default.
- W20348850 hasAuthorship W20348850A5090250975 @default.
- W20348850 hasConcept C126322002 @default.
- W20348850 hasConcept C203014093 @default.
- W20348850 hasConcept C2776694085 @default.
- W20348850 hasConcept C2776755627 @default.
- W20348850 hasConcept C2776760755 @default.
- W20348850 hasConcept C2776912625 @default.
- W20348850 hasConcept C2778330430 @default.
- W20348850 hasConcept C2779075594 @default.
- W20348850 hasConcept C2779134260 @default.
- W20348850 hasConcept C2779912601 @default.
- W20348850 hasConcept C2779972918 @default.
- W20348850 hasConcept C2780401358 @default.
- W20348850 hasConcept C2911091166 @default.
- W20348850 hasConcept C71924100 @default.
- W20348850 hasConceptScore W20348850C126322002 @default.
- W20348850 hasConceptScore W20348850C203014093 @default.
- W20348850 hasConceptScore W20348850C2776694085 @default.
- W20348850 hasConceptScore W20348850C2776755627 @default.
- W20348850 hasConceptScore W20348850C2776760755 @default.
- W20348850 hasConceptScore W20348850C2776912625 @default.
- W20348850 hasConceptScore W20348850C2778330430 @default.
- W20348850 hasConceptScore W20348850C2779075594 @default.
- W20348850 hasConceptScore W20348850C2779134260 @default.
- W20348850 hasConceptScore W20348850C2779912601 @default.
- W20348850 hasConceptScore W20348850C2779972918 @default.
- W20348850 hasConceptScore W20348850C2780401358 @default.
- W20348850 hasConceptScore W20348850C2911091166 @default.
- W20348850 hasConceptScore W20348850C71924100 @default.
- W20348850 hasIssue "3" @default.
- W20348850 hasLocation W203488501 @default.
- W20348850 hasOpenAccess W20348850 @default.
- W20348850 hasPrimaryLocation W203488501 @default.
- W20348850 hasRelatedWork W110475813 @default.
- W20348850 hasRelatedWork W1452338814 @default.
- W20348850 hasRelatedWork W20348850 @default.
- W20348850 hasRelatedWork W2044770659 @default.
- W20348850 hasRelatedWork W2051005234 @default.
- W20348850 hasRelatedWork W2088007149 @default.
- W20348850 hasRelatedWork W2110249745 @default.
- W20348850 hasRelatedWork W2116971739 @default.
- W20348850 hasRelatedWork W2167396782 @default.
- W20348850 hasRelatedWork W2342185396 @default.
- W20348850 hasVolume "78" @default.
- W20348850 isParatext "false" @default.
- W20348850 isRetracted "false" @default.
- W20348850 magId "20348850" @default.
- W20348850 workType "article" @default.