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• W2034887654 abstract "Background Lymph node ratio (LNR) has been associated with long-term survival in patients with pancreatic adenocarcinoma; however, this has not been demonstrated in other periampullary malignancies. The purpose of this study was to determine if LNR is associated with survival in other periampullary malignancies. Methods A retrospective review of a prospective database of 522 pancreaticoduodenectomies (PDs) performed between 1988 and 2007 was undertaken. Clinicopathologic data were collected, and LNR was calculated. Patients with positive lymph node (LN) status were placed into the following groups: (1) LNR = 0; (2) LNR ≤0.2; (3) LNR ≤0.4; and (4) LNR >0.4. Results Of the 364 malignancies identified, there were 219 (60%) pancreatic adenocarcinomas, 36 (10%) duodenal adenocarcinomas, 75 (21%) ampullary adenocarcinomas, and 35 (10%) cholangiocarcinomas. Positive LN status affected patient survival in all malignancies studied. Increasing LNR is associated with decreased survival in PA (P = .03) and AA (P = .04). Conclusions Positive LN status in all patients with periampullary malignancies is associated with worse survival rates than in those with no evidence of disease. LNR is inversely associated with survival rates in pancreatic and ampullary adenocarcinoma patients." @default.
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• W2034887654 date "2009-03-01" @default.
• W2034887654 modified "2023-10-16" @default.
• W2034887654 title "Does lymph node ratio impact survival in resected periampullary malignancies?" @default.
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• W2034887654 doi "https://doi.org/10.1016/j.amjsurg.2008.11.010" @default.
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