Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034889934> ?p ?o ?g. }
- W2034889934 endingPage "61" @default.
- W2034889934 startingPage "58" @default.
- W2034889934 abstract "Sodium metabisulfite (SMB, Na(2)S(2)O(5)) is widely used in the food and pharmaceutical industries, because of its ability to inhibit proliferation of microorganisms and its antioxidant properties. We have evaluated the genotoxic effects of SMB on different tissues of the mouse, by use of the comet assay (liver and blood cells) and the micronucleus test (blood and bone marrow cells). For all tissues, significant increases in damage index and damage frequency values were observed in the SMB-treated groups (1 and 2g/kg doses) compared to the control animals. The Kruskal-Wallis test showed that the mean micronucleus frequencies in peripheral blood and bone marrow cells of mice treated with the highest dose of SMB (2g/kg) showed significant increases, when compared with controls, and a significant reduction in the ratio of polychromatic to normochromatic erythrocytes was also seen. No difference in results between sexes was observed. Our results show that high oral doses of SMB may pose a genotoxic risk." @default.
- W2034889934 created "2016-06-24" @default.
- W2034889934 creator A5010810121 @default.
- W2034889934 creator A5011049279 @default.
- W2034889934 creator A5025072859 @default.
- W2034889934 creator A5030438659 @default.
- W2034889934 creator A5045222622 @default.
- W2034889934 creator A5049660091 @default.
- W2034889934 creator A5082369044 @default.
- W2034889934 date "2011-02-01" @default.
- W2034889934 modified "2023-10-01" @default.
- W2034889934 title "Genotoxicity of sodium metabisulfite in mouse tissues evaluated by the comet assay and the micronucleus test" @default.
- W2034889934 cites W140031919 @default.
- W2034889934 cites W1602702855 @default.
- W2034889934 cites W1969410500 @default.
- W2034889934 cites W1988912319 @default.
- W2034889934 cites W1992127586 @default.
- W2034889934 cites W1995960307 @default.
- W2034889934 cites W1997001691 @default.
- W2034889934 cites W1997747008 @default.
- W2034889934 cites W2001952894 @default.
- W2034889934 cites W2013439363 @default.
- W2034889934 cites W2014425417 @default.
- W2034889934 cites W2028970418 @default.
- W2034889934 cites W2033251540 @default.
- W2034889934 cites W2039943070 @default.
- W2034889934 cites W2043856334 @default.
- W2034889934 cites W2064058589 @default.
- W2034889934 cites W2078315838 @default.
- W2034889934 cites W2078986485 @default.
- W2034889934 cites W2087723613 @default.
- W2034889934 cites W2092629964 @default.
- W2034889934 cites W2161721368 @default.
- W2034889934 doi "https://doi.org/10.1016/j.mrgentox.2010.12.007" @default.
- W2034889934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21185391" @default.
- W2034889934 hasPublicationYear "2011" @default.
- W2034889934 type Work @default.
- W2034889934 sameAs 2034889934 @default.
- W2034889934 citedByCount "17" @default.
- W2034889934 countsByYear W20348899342012 @default.
- W2034889934 countsByYear W20348899342013 @default.
- W2034889934 countsByYear W20348899342014 @default.
- W2034889934 countsByYear W20348899342015 @default.
- W2034889934 countsByYear W20348899342016 @default.
- W2034889934 countsByYear W20348899342017 @default.
- W2034889934 countsByYear W20348899342019 @default.
- W2034889934 countsByYear W20348899342020 @default.
- W2034889934 countsByYear W20348899342021 @default.
- W2034889934 countsByYear W20348899342022 @default.
- W2034889934 countsByYear W20348899342023 @default.
- W2034889934 crossrefType "journal-article" @default.
- W2034889934 hasAuthorship W2034889934A5010810121 @default.
- W2034889934 hasAuthorship W2034889934A5011049279 @default.
- W2034889934 hasAuthorship W2034889934A5025072859 @default.
- W2034889934 hasAuthorship W2034889934A5030438659 @default.
- W2034889934 hasAuthorship W2034889934A5045222622 @default.
- W2034889934 hasAuthorship W2034889934A5049660091 @default.
- W2034889934 hasAuthorship W2034889934A5082369044 @default.
- W2034889934 hasConcept C141710004 @default.
- W2034889934 hasConcept C143425029 @default.
- W2034889934 hasConcept C16685009 @default.
- W2034889934 hasConcept C178790620 @default.
- W2034889934 hasConcept C185592680 @default.
- W2034889934 hasConcept C203014093 @default.
- W2034889934 hasConcept C2778004101 @default.
- W2034889934 hasConcept C2778920651 @default.
- W2034889934 hasConcept C2778959862 @default.
- W2034889934 hasConcept C2780007613 @default.
- W2034889934 hasConcept C2780358455 @default.
- W2034889934 hasConcept C29730261 @default.
- W2034889934 hasConcept C31903555 @default.
- W2034889934 hasConcept C33070731 @default.
- W2034889934 hasConcept C36681516 @default.
- W2034889934 hasConcept C45080847 @default.
- W2034889934 hasConcept C552990157 @default.
- W2034889934 hasConcept C55493867 @default.
- W2034889934 hasConcept C71924100 @default.
- W2034889934 hasConcept C86803240 @default.
- W2034889934 hasConcept C98274493 @default.
- W2034889934 hasConceptScore W2034889934C141710004 @default.
- W2034889934 hasConceptScore W2034889934C143425029 @default.
- W2034889934 hasConceptScore W2034889934C16685009 @default.
- W2034889934 hasConceptScore W2034889934C178790620 @default.
- W2034889934 hasConceptScore W2034889934C185592680 @default.
- W2034889934 hasConceptScore W2034889934C203014093 @default.
- W2034889934 hasConceptScore W2034889934C2778004101 @default.
- W2034889934 hasConceptScore W2034889934C2778920651 @default.
- W2034889934 hasConceptScore W2034889934C2778959862 @default.
- W2034889934 hasConceptScore W2034889934C2780007613 @default.
- W2034889934 hasConceptScore W2034889934C2780358455 @default.
- W2034889934 hasConceptScore W2034889934C29730261 @default.
- W2034889934 hasConceptScore W2034889934C31903555 @default.
- W2034889934 hasConceptScore W2034889934C33070731 @default.
- W2034889934 hasConceptScore W2034889934C36681516 @default.
- W2034889934 hasConceptScore W2034889934C45080847 @default.
- W2034889934 hasConceptScore W2034889934C552990157 @default.
- W2034889934 hasConceptScore W2034889934C55493867 @default.
- W2034889934 hasConceptScore W2034889934C71924100 @default.