Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034892899> ?p ?o ?g. }
- W2034892899 endingPage "7" @default.
- W2034892899 startingPage "1" @default.
- W2034892899 abstract "NOTCH4 is a developmentally expressed gene recently reported to be in linkage disequilibrium (LD) with schizophrenia. We investigated this finding in our sample of subjects, focusing on an exonic (CTG)(n) polymorphism, examining not only the association of this polymorphism with the disease phenotype, but also its effect on frontal lobe brain morphology and cognitive function in both affected individuals and a psychiatrically normal comparison group. While we did not find any association or LD with schizophrenia, we identified striking effects of NOTCH4 variability on the trait measures. Within the respective schizophrenia and comparison groups, NOTCH4 allelic variability was correlated with differences in measures of frontal lobe cognitive performance and frontal lobe brain tissue volumes that were intuitively congruent. These within-group effects, however, were in opposite directions across groups. These findings may reflect the interaction of NOTCH4 with the underlying genetic and phenotypic complexity that characterizes both schizophrenia and normal cognition and brain development." @default.
- W2034892899 created "2016-06-24" @default.
- W2034892899 creator A5045387664 @default.
- W2034892899 creator A5064042667 @default.
- W2034892899 creator A5073304224 @default.
- W2034892899 creator A5091277767 @default.
- W2034892899 creator A5091820416 @default.
- W2034892899 date "2003-01-22" @default.
- W2034892899 modified "2023-10-10" @default.
- W2034892899 title "NOTCH4 and the frontal lobe in schizophrenia" @default.
- W2034892899 cites W1485161311 @default.
- W2034892899 cites W1521186525 @default.
- W2034892899 cites W1528322675 @default.
- W2034892899 cites W1568993576 @default.
- W2034892899 cites W1963926989 @default.
- W2034892899 cites W1965871695 @default.
- W2034892899 cites W1969380437 @default.
- W2034892899 cites W1971744121 @default.
- W2034892899 cites W1974670959 @default.
- W2034892899 cites W1980001686 @default.
- W2034892899 cites W1984059331 @default.
- W2034892899 cites W1990005524 @default.
- W2034892899 cites W1990234390 @default.
- W2034892899 cites W1998328043 @default.
- W2034892899 cites W2002477781 @default.
- W2034892899 cites W2009077748 @default.
- W2034892899 cites W2019410645 @default.
- W2034892899 cites W2020854296 @default.
- W2034892899 cites W2031020345 @default.
- W2034892899 cites W2032866243 @default.
- W2034892899 cites W2033233404 @default.
- W2034892899 cites W2037379301 @default.
- W2034892899 cites W2041576587 @default.
- W2034892899 cites W2061995731 @default.
- W2034892899 cites W2066143011 @default.
- W2034892899 cites W2067097027 @default.
- W2034892899 cites W2067376187 @default.
- W2034892899 cites W2068597012 @default.
- W2034892899 cites W2074446477 @default.
- W2034892899 cites W2075746584 @default.
- W2034892899 cites W2077864321 @default.
- W2034892899 cites W2080755756 @default.
- W2034892899 cites W2082133442 @default.
- W2034892899 cites W2090156827 @default.
- W2034892899 cites W2092034939 @default.
- W2034892899 cites W2093081731 @default.
- W2034892899 cites W2109022931 @default.
- W2034892899 cites W2119570838 @default.
- W2034892899 cites W2127700562 @default.
- W2034892899 cites W2132273199 @default.
- W2034892899 cites W2133469704 @default.
- W2034892899 cites W2138291491 @default.
- W2034892899 cites W2138927557 @default.
- W2034892899 cites W2139733283 @default.
- W2034892899 cites W2143381192 @default.
- W2034892899 cites W2146660065 @default.
- W2034892899 cites W2153087078 @default.
- W2034892899 cites W2153525031 @default.
- W2034892899 cites W2154861644 @default.
- W2034892899 cites W2400057008 @default.
- W2034892899 cites W2413084273 @default.
- W2034892899 doi "https://doi.org/10.1002/ajmg.b.10071" @default.
- W2034892899 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12627456" @default.
- W2034892899 hasPublicationYear "2003" @default.
- W2034892899 type Work @default.
- W2034892899 sameAs 2034892899 @default.
- W2034892899 citedByCount "42" @default.
- W2034892899 countsByYear W20348928992012 @default.
- W2034892899 countsByYear W20348928992013 @default.
- W2034892899 countsByYear W20348928992014 @default.
- W2034892899 countsByYear W20348928992015 @default.
- W2034892899 countsByYear W20348928992016 @default.
- W2034892899 countsByYear W20348928992017 @default.
- W2034892899 countsByYear W20348928992018 @default.
- W2034892899 countsByYear W20348928992021 @default.
- W2034892899 crossrefType "journal-article" @default.
- W2034892899 hasAuthorship W2034892899A5045387664 @default.
- W2034892899 hasAuthorship W2034892899A5064042667 @default.
- W2034892899 hasAuthorship W2034892899A5073304224 @default.
- W2034892899 hasAuthorship W2034892899A5091277767 @default.
- W2034892899 hasAuthorship W2034892899A5091820416 @default.
- W2034892899 hasConcept C104317684 @default.
- W2034892899 hasConcept C106934330 @default.
- W2034892899 hasConcept C118552586 @default.
- W2034892899 hasConcept C127716648 @default.
- W2034892899 hasConcept C15744967 @default.
- W2034892899 hasConcept C169760540 @default.
- W2034892899 hasConcept C169900460 @default.
- W2034892899 hasConcept C180754005 @default.
- W2034892899 hasConcept C197754878 @default.
- W2034892899 hasConcept C199360897 @default.
- W2034892899 hasConcept C2776412080 @default.
- W2034892899 hasConcept C2777127467 @default.
- W2034892899 hasConcept C2778186239 @default.
- W2034892899 hasConcept C2779727114 @default.
- W2034892899 hasConcept C2781099131 @default.
- W2034892899 hasConcept C35605836 @default.
- W2034892899 hasConcept C41008148 @default.