FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034896017> ?p ?o ?g. }

• W2034896017 endingPage "266" @default.
• W2034896017 startingPage "259" @default.
• W2034896017 abstract "Whole cell patch clamp recordings were made from type I cells of the neonatal rat carotid body, isolated and maintained in primary culture for up to 48 h. Depolarizing voltage steps applied from a holding potential of -70 mV evoked outward currents positive to approximately -30 mV. Currents were strongly blocked by extracellular tetraethylammonium (25 mM), and were therefore attributed to activation of voltage-dependent K+ channels. Currents were also suppressed by 4-aminopyridine, removal of extracellular Ca2+, and replacement of extracellular Ca2+ with Ba2+. These results suggest there are Ca2(+)-dependent and Ca2(+)-independent components of the K+ currents. No evidence was found to suggest that ATP-sensitive K+ channels were present. The effects of 3 chemoexcitatory agents (NaCN, almitrine and reduced extracellular pH) on K+ currents in isolated type I cells were investigated. All three agents suppressed K+ currents to similar degrees. The effects of lowered pH and NaCN were reversible, and NaCN-induced reductions occurred regardless of the presence of intracellular ATP. The effect of almitrine was irreversible for up to 30 min of recording. It is concluded that the reduction of K+ currents by chemoexcitants may play a role in the mechanism of chemotransduction in the carotid body." @default.
• W2034896017 created "2016-06-24" @default.
• W2034896017 creator A5021541994 @default.
• W2034896017 creator A5063654973 @default.
• W2034896017 date "1990-07-01" @default.
• W2034896017 modified "2023-09-26" @default.
• W2034896017 title "Potassium currents recorded in type I carotid body cells from the neonatal rat and their modulation by chemoexcitatory agents" @default.
• W2034896017 cites W1812214972 @default.
• W2034896017 cites W1970283276 @default.
• W2034896017 cites W1980432749 @default.
• W2034896017 cites W1983444296 @default.
• W2034896017 cites W1983636741 @default.
• W2034896017 cites W1988521522 @default.
• W2034896017 cites W1990845205 @default.
• W2034896017 cites W2001409949 @default.
• W2034896017 cites W2001848789 @default.
• W2034896017 cites W2007642104 @default.
• W2034896017 cites W2009078172 @default.
• W2034896017 cites W2009667219 @default.
• W2034896017 cites W2013075447 @default.
• W2034896017 cites W2023384807 @default.
• W2034896017 cites W2031001660 @default.
• W2034896017 cites W2056527299 @default.
• W2034896017 cites W2059546190 @default.
• W2034896017 cites W2064953660 @default.
• W2034896017 cites W2069594046 @default.
• W2034896017 cites W2103653522 @default.
• W2034896017 cites W2148255642 @default.
• W2034896017 cites W2264646263 @default.
• W2034896017 cites W2422092175 @default.
• W2034896017 doi "https://doi.org/10.1016/0006-8993(90)91470-2" @default.
• W2034896017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2224527" @default.
• W2034896017 hasPublicationYear "1990" @default.
• W2034896017 type Work @default.
• W2034896017 sameAs 2034896017 @default.
• W2034896017 citedByCount "58" @default.
• W2034896017 countsByYear W20348960172013 @default.
• W2034896017 countsByYear W20348960172015 @default.
• W2034896017 countsByYear W20348960172017 @default.
• W2034896017 countsByYear W20348960172019 @default.
• W2034896017 crossrefType "journal-article" @default.
• W2034896017 hasAuthorship W2034896017A5021541994 @default.
• W2034896017 hasAuthorship W2034896017A5063654973 @default.
• W2034896017 hasConcept C12554922 @default.
• W2034896017 hasConcept C126322002 @default.
• W2034896017 hasConcept C134018914 @default.
• W2034896017 hasConcept C147944092 @default.
• W2034896017 hasConcept C178790620 @default.
• W2034896017 hasConcept C181911157 @default.
• W2034896017 hasConcept C185263204 @default.
• W2034896017 hasConcept C185592680 @default.
• W2034896017 hasConcept C2778113364 @default.
• W2034896017 hasConcept C2781295685 @default.
• W2034896017 hasConcept C28406088 @default.
• W2034896017 hasConcept C4141045 @default.
• W2034896017 hasConcept C517785266 @default.
• W2034896017 hasConcept C55493867 @default.
• W2034896017 hasConcept C71924100 @default.
• W2034896017 hasConcept C79879829 @default.
• W2034896017 hasConcept C83743174 @default.
• W2034896017 hasConcept C86803240 @default.
• W2034896017 hasConceptScore W2034896017C12554922 @default.
• W2034896017 hasConceptScore W2034896017C126322002 @default.
• W2034896017 hasConceptScore W2034896017C134018914 @default.
• W2034896017 hasConceptScore W2034896017C147944092 @default.
• W2034896017 hasConceptScore W2034896017C178790620 @default.
• W2034896017 hasConceptScore W2034896017C181911157 @default.
• W2034896017 hasConceptScore W2034896017C185263204 @default.
• W2034896017 hasConceptScore W2034896017C185592680 @default.
• W2034896017 hasConceptScore W2034896017C2778113364 @default.
• W2034896017 hasConceptScore W2034896017C2781295685 @default.
• W2034896017 hasConceptScore W2034896017C28406088 @default.
• W2034896017 hasConceptScore W2034896017C4141045 @default.
• W2034896017 hasConceptScore W2034896017C517785266 @default.
• W2034896017 hasConceptScore W2034896017C55493867 @default.
• W2034896017 hasConceptScore W2034896017C71924100 @default.
• W2034896017 hasConceptScore W2034896017C79879829 @default.
• W2034896017 hasConceptScore W2034896017C83743174 @default.
• W2034896017 hasConceptScore W2034896017C86803240 @default.
• W2034896017 hasIssue "2" @default.
• W2034896017 hasLocation W20348960171 @default.
• W2034896017 hasLocation W20348960172 @default.
• W2034896017 hasOpenAccess W2034896017 @default.
• W2034896017 hasPrimaryLocation W20348960171 @default.
• W2034896017 hasRelatedWork W111279135 @default.
• W2034896017 hasRelatedWork W124621800 @default.
• W2034896017 hasRelatedWork W1981906372 @default.
• W2034896017 hasRelatedWork W2029261681 @default.
• W2034896017 hasRelatedWork W2047225757 @default.
• W2034896017 hasRelatedWork W2055830121 @default.
• W2034896017 hasRelatedWork W2068406497 @default.
• W2034896017 hasRelatedWork W2087015066 @default.
• W2034896017 hasRelatedWork W2088281397 @default.
• W2034896017 hasRelatedWork W2227486288 @default.
• W2034896017 hasVolume "522" @default.
• W2034896017 isParatext "false" @default.
• W2034896017 isRetracted "false" @default.
• W2034896017 magId "2034896017" @default.

• next