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- W2034911237 abstract "Hepatitis C (HCV) coinfection is the leading cause of liver-related morbidity and is a leading cause of mortality in human immunodeficiency virus (HIV)-infected individuals in the antiretroviral therapy era. Direct-acting antiviral (DAA) therapies are transforming how HCV is treated with significant improvements in efficacy and tolerability. In this article, DAA agents expected to be available in 2014 are reviewed, including telaprevir, boceprevir, sofosbuvir, simeprevir, faldaprevir, and daclatasvir. Available data regarding clinical efficacy, adverse effects, and drug interactions in HIV-HCV coinfection are discussed. The management of adverse effects of HCV therapy and treatment considerations in patients with cirrhosis are also reviewed." @default.
- W2034911237 created "2016-06-24" @default.
- W2034911237 creator A5051169100 @default.
- W2034911237 creator A5065304569 @default.
- W2034911237 date "2013-11-24" @default.
- W2034911237 modified "2023-10-11" @default.
- W2034911237 title "Treatment of Genotype 1 HCV Infection in the HIV Coinfected Patient in 2014" @default.
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- W2034911237 doi "https://doi.org/10.1007/s11904-013-0182-8" @default.
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