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- W2034911276 abstract "It is well known that yeast cells survive environmental stresses such as desiccation and freezing and there is evidence that these phenomena may be related to the presence of trehalose in the cells. However, the molecular mechanism by which trehalose might exert an influence on cell functions remains unknown. In this report, thermogravimetry and differential thermal analysis were used to estimate the amount of bound water in yeast cells. It is shown that when the trehalose content is greater than 2-3% of the cell dry weight, the amount of bound water is drastically decreased and the viability of the dried cells is increased. This implies that a major portion of the bound water is replaced by trehalose. In addition, measurements of the NMR spin-lattice relaxation time of the intracellular water protons show that trehalose acts as a water-structuring agent in hydrated yeast cells. This dual role is essential for high resistance to water stress in yeast cells." @default.
- W2034911276 created "2016-06-24" @default.
- W2034911276 creator A5000171213 @default.
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- W2034911276 date "1999-08-01" @default.
- W2034911276 modified "2023-09-25" @default.
- W2034911276 title "A Dual Role for Intracellular Trehalose in the Resistance of Yeast Cells to Water Stress" @default.
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- W2034911276 doi "https://doi.org/10.1006/cryo.1999.2188" @default.
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