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• W2034921848 abstract "Treatment of platelets or red cells with small amounts of phospholipase C from Clostridium welchii enables both cells, prior to the onset of lysis, to stimulate prothrombin conversion by coagulation factor Xa and Va in the presence of calcium. Phospholipase C treatment of both cells also exposes significant amounts of phosphatidylserine at the outer surface. The level of phosphatidic acid formed from diglycerides produced by phospholipase C action, is similar to that formed in activated platelets upon triggering the phosphatidylinositol cycle. A possible involvement of this cycle to activate platelets to become more procoagulant is discussed." @default.
• W2034921848 created "2016-06-24" @default.
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• W2034921848 date "1983-12-01" @default.
• W2034921848 modified "2023-09-24" @default.
• W2034921848 title "Stimulation of prothrombinase activity of platelets and erythrocytes by sub-lytic treatment with phospholipase C from Clostridium welchii" @default.
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• W2034921848 doi "https://doi.org/10.1016/0006-291x(83)91668-6" @default.
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