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• W2034922653 abstract "Atomic force microscopy has been used to probe the surface nanostructures of severe acute respiratory syndrome coronavirus (SARS-CoV). Single crown-like virion was directly visualized and quantitative measurements of the dimensions for the structural proteins were provided. A corona of large, distinctive spikes in the envelope was measured after treatment with hydroxyoctanoic acid. High-resolution images revealed that the surface of each single SARS-CoV was surrounded with at least 15 spherical spikes having a diameter of 7.29 ± 0.73 nm, which is in close agreement with that of S glycoproteins earlier predicted through the genomes of SARS-CoV. This study represents the first direct characterization of the surface ultrastructures of SARS-CoV particles at the nanometre scale and offers new prospects for mapping viral surface properties." @default.
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• W2034922653 date "2005-12-01" @default.
• W2034922653 modified "2023-10-03" @default.
• W2034922653 title "Surface ultrastructure of SARS coronavirus revealed by atomic force microscopy" @default.
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• W2034922653 doi "https://doi.org/10.1111/j.1462-5822.2005.00593.x" @default.
• W2034922653 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7162285" @default.
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