Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034926884> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2034926884 endingPage "140" @default.
- W2034926884 startingPage "131" @default.
- W2034926884 abstract "The response of mouse bladders to multifraction irradiation was assessed from increases in urination frequency or the reduction in bladder capacity after irradiation. A range of electron doses were given as 1, 2, 5, 10 or 20 equal fractions in overall treatment times of 1–2 weeks. Dose-related increases in urination frequency were measured from 10 to 14 months after irradiation and a dose-related reduction in bladder capacity (at inflation pressures of 20 mm Hg) was apparent at the time of sacrifice. The extent of repair of sublethal and potentially lethal damage was estimated from a comparison of the isoeffective doses in fractionated regimes and single dose treatments. After small doses per fraction (2.5–6 Gy), the extent of repair in bladder was very similar to that in mouse skin. After larger doses per fraction (>8 Gy) slightly more repair was seen in bladder than skin. Linear-quadratic analysis of the data suggests quite a high value for the ratio α/β, in the region of 5 to 10 Gy. This is higher than the α/β ratios which have been reported for most other slowly dividing normal tissues. The response of mouse bladders to multifraction irradiation was assessed from increases in urination frequency or the reduction in bladder capacity after irradiation. A range of electron doses were given as 1, 2, 5, 10 or 20 equal fractions in overall treatment times of 1–2 weeks. Dose-related increases in urination frequency were measured from 10 to 14 months after irradiation and a dose-related reduction in bladder capacity (at inflation pressures of 20 mm Hg) was apparent at the time of sacrifice. The extent of repair of sublethal and potentially lethal damage was estimated from a comparison of the isoeffective doses in fractionated regimes and single dose treatments. After small doses per fraction (2.5–6 Gy), the extent of repair in bladder was very similar to that in mouse skin. After larger doses per fraction (>8 Gy) slightly more repair was seen in bladder than skin. Linear-quadratic analysis of the data suggests quite a high value for the ratio α/β, in the region of 5 to 10 Gy. This is higher than the α/β ratios which have been reported for most other slowly dividing normal tissues." @default.
- W2034926884 created "2016-06-24" @default.
- W2034926884 creator A5007141114 @default.
- W2034926884 creator A5015292429 @default.
- W2034926884 creator A5082057825 @default.
- W2034926884 date "1984-08-01" @default.
- W2034926884 modified "2023-10-18" @default.
- W2034926884 title "Multifraction irradiation of mouse bladders" @default.
- W2034926884 cites W1983231739 @default.
- W2034926884 cites W1999194764 @default.
- W2034926884 cites W2009880393 @default.
- W2034926884 cites W2010716171 @default.
- W2034926884 cites W2016871222 @default.
- W2034926884 cites W2025913924 @default.
- W2034926884 cites W2029517266 @default.
- W2034926884 cites W2032591825 @default.
- W2034926884 cites W2036139223 @default.
- W2034926884 cites W2037874910 @default.
- W2034926884 cites W2061004798 @default.
- W2034926884 cites W2063480100 @default.
- W2034926884 cites W2078466258 @default.
- W2034926884 cites W2091256057 @default.
- W2034926884 cites W2093443954 @default.
- W2034926884 cites W2113709744 @default.
- W2034926884 cites W2137602207 @default.
- W2034926884 cites W2139035521 @default.
- W2034926884 cites W2140526417 @default.
- W2034926884 cites W2155646363 @default.
- W2034926884 cites W2163342607 @default.
- W2034926884 cites W4238480726 @default.
- W2034926884 cites W4298344660 @default.
- W2034926884 doi "https://doi.org/10.1016/s0167-8140(84)80049-3" @default.
- W2034926884 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6505283" @default.
- W2034926884 hasPublicationYear "1984" @default.
- W2034926884 type Work @default.
- W2034926884 sameAs 2034926884 @default.
- W2034926884 citedByCount "37" @default.
- W2034926884 countsByYear W20349268842012 @default.
- W2034926884 countsByYear W20349268842013 @default.
- W2034926884 countsByYear W20349268842016 @default.
- W2034926884 countsByYear W20349268842018 @default.
- W2034926884 countsByYear W20349268842021 @default.
- W2034926884 countsByYear W20349268842022 @default.
- W2034926884 countsByYear W20349268842023 @default.
- W2034926884 crossrefType "journal-article" @default.
- W2034926884 hasAuthorship W2034926884A5007141114 @default.
- W2034926884 hasAuthorship W2034926884A5015292429 @default.
- W2034926884 hasAuthorship W2034926884A5082057825 @default.
- W2034926884 hasConcept C105702510 @default.
- W2034926884 hasConcept C111337013 @default.
- W2034926884 hasConcept C121332964 @default.
- W2034926884 hasConcept C125118446 @default.
- W2034926884 hasConcept C126894567 @default.
- W2034926884 hasConcept C141071460 @default.
- W2034926884 hasConcept C175768497 @default.
- W2034926884 hasConcept C185544564 @default.
- W2034926884 hasConcept C2779762690 @default.
- W2034926884 hasConcept C2989005 @default.
- W2034926884 hasConcept C509974204 @default.
- W2034926884 hasConcept C71924100 @default.
- W2034926884 hasConcept C77411442 @default.
- W2034926884 hasConcept C86803240 @default.
- W2034926884 hasConceptScore W2034926884C105702510 @default.
- W2034926884 hasConceptScore W2034926884C111337013 @default.
- W2034926884 hasConceptScore W2034926884C121332964 @default.
- W2034926884 hasConceptScore W2034926884C125118446 @default.
- W2034926884 hasConceptScore W2034926884C126894567 @default.
- W2034926884 hasConceptScore W2034926884C141071460 @default.
- W2034926884 hasConceptScore W2034926884C175768497 @default.
- W2034926884 hasConceptScore W2034926884C185544564 @default.
- W2034926884 hasConceptScore W2034926884C2779762690 @default.
- W2034926884 hasConceptScore W2034926884C2989005 @default.
- W2034926884 hasConceptScore W2034926884C509974204 @default.
- W2034926884 hasConceptScore W2034926884C71924100 @default.
- W2034926884 hasConceptScore W2034926884C77411442 @default.
- W2034926884 hasConceptScore W2034926884C86803240 @default.
- W2034926884 hasIssue "2" @default.
- W2034926884 hasLocation W20349268841 @default.
- W2034926884 hasLocation W20349268842 @default.
- W2034926884 hasOpenAccess W2034926884 @default.
- W2034926884 hasPrimaryLocation W20349268841 @default.
- W2034926884 hasRelatedWork W188685642 @default.
- W2034926884 hasRelatedWork W1964117362 @default.
- W2034926884 hasRelatedWork W2334311845 @default.
- W2034926884 hasRelatedWork W2356872517 @default.
- W2034926884 hasRelatedWork W2403329915 @default.
- W2034926884 hasRelatedWork W2409676275 @default.
- W2034926884 hasRelatedWork W2438822596 @default.
- W2034926884 hasRelatedWork W2442980851 @default.
- W2034926884 hasRelatedWork W2468337545 @default.
- W2034926884 hasRelatedWork W3031205980 @default.
- W2034926884 hasVolume "2" @default.
- W2034926884 isParatext "false" @default.
- W2034926884 isRetracted "false" @default.
- W2034926884 magId "2034926884" @default.
- W2034926884 workType "article" @default.