Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034933057> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2034933057 endingPage "26" @default.
- W2034933057 startingPage "22" @default.
- W2034933057 abstract "From our own experience we have seen that over the past 60 years topical delivery of drugs with its advantages and disadvantages has become much more widely understood and much more is now known about the disposition of drugs in the skin. Today, pharmaceutical scientists produce dermatological vehicles which are tailored to patients’ needs and better appreciate how the formulation may affect rates of drug delivery, and ultimately, efficacy and safety. The guidelines for developing a New Chemical Entity (NCE) to be administered by the topical route are rather straightforward. What appears to be less well understood are the pathways for development, and the regulatory routes for topical formulations of a known established Active Pharmaceutical Ingredient (API) either in a new formulation, at a different concentration, or with APIs where topical administration is an alternative route of administration. This article provides guidance, on the regulatory routes which can help achieve marketing approval in Europe for topical formulations, with particular emphasis on clinical development. Some comments on NCE's will be given, and further detail is provided in cases where the topical route is a new method of administration for delivering a known API." @default.
- W2034933057 created "2016-06-24" @default.
- W2034933057 creator A5057884872 @default.
- W2034933057 creator A5078012800 @default.
- W2034933057 creator A5090208325 @default.
- W2034933057 date "2012-10-01" @default.
- W2034933057 modified "2023-10-16" @default.
- W2034933057 title "The development and registration of topical pharmaceuticals" @default.
- W2034933057 cites W1966026615 @default.
- W2034933057 cites W2009459031 @default.
- W2034933057 cites W2009609623 @default.
- W2034933057 cites W2028704484 @default.
- W2034933057 cites W2033142371 @default.
- W2034933057 cites W2045018181 @default.
- W2034933057 cites W2045800643 @default.
- W2034933057 cites W2061791041 @default.
- W2034933057 cites W2070641990 @default.
- W2034933057 cites W2123230121 @default.
- W2034933057 cites W2158838801 @default.
- W2034933057 doi "https://doi.org/10.1016/j.ijpharm.2012.03.052" @default.
- W2034933057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22486961" @default.
- W2034933057 hasPublicationYear "2012" @default.
- W2034933057 type Work @default.
- W2034933057 sameAs 2034933057 @default.
- W2034933057 citedByCount "20" @default.
- W2034933057 countsByYear W20349330572012 @default.
- W2034933057 countsByYear W20349330572013 @default.
- W2034933057 countsByYear W20349330572014 @default.
- W2034933057 countsByYear W20349330572015 @default.
- W2034933057 countsByYear W20349330572017 @default.
- W2034933057 countsByYear W20349330572018 @default.
- W2034933057 countsByYear W20349330572019 @default.
- W2034933057 countsByYear W20349330572021 @default.
- W2034933057 countsByYear W20349330572023 @default.
- W2034933057 crossrefType "journal-article" @default.
- W2034933057 hasAuthorship W2034933057A5057884872 @default.
- W2034933057 hasAuthorship W2034933057A5078012800 @default.
- W2034933057 hasAuthorship W2034933057A5090208325 @default.
- W2034933057 hasConcept C112930515 @default.
- W2034933057 hasConcept C144133560 @default.
- W2034933057 hasConcept C185592680 @default.
- W2034933057 hasConcept C2779652045 @default.
- W2034933057 hasConcept C2984430287 @default.
- W2034933057 hasConcept C3018890749 @default.
- W2034933057 hasConcept C41008148 @default.
- W2034933057 hasConcept C43617362 @default.
- W2034933057 hasConcept C45904493 @default.
- W2034933057 hasConcept C71924100 @default.
- W2034933057 hasConcept C77281830 @default.
- W2034933057 hasConcept C98274493 @default.
- W2034933057 hasConceptScore W2034933057C112930515 @default.
- W2034933057 hasConceptScore W2034933057C144133560 @default.
- W2034933057 hasConceptScore W2034933057C185592680 @default.
- W2034933057 hasConceptScore W2034933057C2779652045 @default.
- W2034933057 hasConceptScore W2034933057C2984430287 @default.
- W2034933057 hasConceptScore W2034933057C3018890749 @default.
- W2034933057 hasConceptScore W2034933057C41008148 @default.
- W2034933057 hasConceptScore W2034933057C43617362 @default.
- W2034933057 hasConceptScore W2034933057C45904493 @default.
- W2034933057 hasConceptScore W2034933057C71924100 @default.
- W2034933057 hasConceptScore W2034933057C77281830 @default.
- W2034933057 hasConceptScore W2034933057C98274493 @default.
- W2034933057 hasIssue "1" @default.
- W2034933057 hasLocation W20349330571 @default.
- W2034933057 hasLocation W20349330572 @default.
- W2034933057 hasOpenAccess W2034933057 @default.
- W2034933057 hasPrimaryLocation W20349330571 @default.
- W2034933057 hasRelatedWork W1515626046 @default.
- W2034933057 hasRelatedWork W2064824145 @default.
- W2034933057 hasRelatedWork W2074822656 @default.
- W2034933057 hasRelatedWork W2315703870 @default.
- W2034933057 hasRelatedWork W2339989730 @default.
- W2034933057 hasRelatedWork W2404713588 @default.
- W2034933057 hasRelatedWork W2755463998 @default.
- W2034933057 hasRelatedWork W2801671470 @default.
- W2034933057 hasRelatedWork W2900360385 @default.
- W2034933057 hasRelatedWork W3196116200 @default.
- W2034933057 hasVolume "435" @default.
- W2034933057 isParatext "false" @default.
- W2034933057 isRetracted "false" @default.
- W2034933057 magId "2034933057" @default.
- W2034933057 workType "article" @default.