FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034951351> ?p ?o ?g. }

• W2034951351 endingPage "76" @default.
• W2034951351 startingPage "71" @default.
• W2034951351 abstract "Recently introduced into the market, belimumab (Benlysta) is a monoclonal antibody that has potential clinically efficacious applications for the treatment of lupus nephritis. Lupus nephritis is a major complication of systemic lupus erythematosus (SLE) that can lead to significant illness or even death without proper intervention and treatment. With vast implications through a novel mechanism, belimumab offers a new standard of treatment for physicians in the complications associated with SLE, specifically lupus nephritis. By targeting B cell signaling and maturation, belimumab is able to mitigate the underlying pathological complications surrounding SLE. Phase 3 clinical trials with belimumab have depicted clinically efficacious applications, suggesting belimumab as a revolutionary breakthrough in the treatment armamentarium for practicing clinicians. This article explains the precise mechanism of action of belimumab on the soluble protein BlyS that plays a major role in the pathogenesis of lupus nephritis. In addition, the extensive pharmacokinetics and clinical implications are exemplified in this review with belimumab's comparison with standard therapeutic guidelines for the treatment of lupus nephritis." @default.
• W2034951351 created "2016-06-24" @default.
• W2034951351 creator A5034174597 @default.
• W2034951351 creator A5047764619 @default.
• W2034951351 creator A5061540087 @default.
• W2034951351 date "2015-06-01" @default.
• W2034951351 modified "2023-10-01" @default.
• W2034951351 title "Efficacy of novel monoclonal antibody belimumab in the treatment of lupus nephritis" @default.
• W2034951351 cites W1963756694 @default.
• W2034951351 cites W1966161051 @default.
• W2034951351 cites W1968108602 @default.
• W2034951351 cites W1982924102 @default.
• W2034951351 cites W1983432410 @default.
• W2034951351 cites W1996725867 @default.
• W2034951351 cites W2011835981 @default.
• W2034951351 cites W2054077777 @default.
• W2034951351 cites W2058500070 @default.
• W2034951351 cites W2075452125 @default.
• W2034951351 cites W2078800870 @default.
• W2034951351 cites W2126846485 @default.
• W2034951351 cites W2131457901 @default.
• W2034951351 cites W2136149088 @default.
• W2034951351 cites W2144460058 @default.
• W2034951351 cites W2157038471 @default.
• W2034951351 cites W2327446233 @default.
• W2034951351 cites W2327976102 @default.
• W2034951351 doi "https://doi.org/10.4103/0976-500x.155482" @default.
• W2034951351 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4419251" @default.
• W2034951351 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25969652" @default.
• W2034951351 hasPublicationYear "2015" @default.
• W2034951351 type Work @default.
• W2034951351 sameAs 2034951351 @default.
• W2034951351 citedByCount "31" @default.
• W2034951351 countsByYear W20349513512015 @default.
• W2034951351 countsByYear W20349513512016 @default.
• W2034951351 countsByYear W20349513512017 @default.
• W2034951351 countsByYear W20349513512018 @default.
• W2034951351 countsByYear W20349513512019 @default.
• W2034951351 countsByYear W20349513512020 @default.
• W2034951351 countsByYear W20349513512021 @default.
• W2034951351 countsByYear W20349513512022 @default.
• W2034951351 countsByYear W20349513512023 @default.
• W2034951351 crossrefType "journal-article" @default.
• W2034951351 hasAuthorship W2034951351A5034174597 @default.
• W2034951351 hasAuthorship W2034951351A5047764619 @default.
• W2034951351 hasAuthorship W2034951351A5061540087 @default.
• W2034951351 hasBestOaLocation W20349513511 @default.
• W2034951351 hasConcept C126322002 @default.
• W2034951351 hasConcept C159654299 @default.
• W2034951351 hasConcept C163864487 @default.
• W2034951351 hasConcept C170286685 @default.
• W2034951351 hasConcept C203014093 @default.
• W2034951351 hasConcept C2775915377 @default.
• W2034951351 hasConcept C2776912625 @default.
• W2034951351 hasConcept C2777058396 @default.
• W2034951351 hasConcept C2778453870 @default.
• W2034951351 hasConcept C2779134260 @default.
• W2034951351 hasConcept C2779912601 @default.
• W2034951351 hasConcept C2781205201 @default.
• W2034951351 hasConcept C535046627 @default.
• W2034951351 hasConcept C542903549 @default.
• W2034951351 hasConcept C71924100 @default.
• W2034951351 hasConceptScore W2034951351C126322002 @default.
• W2034951351 hasConceptScore W2034951351C159654299 @default.
• W2034951351 hasConceptScore W2034951351C163864487 @default.
• W2034951351 hasConceptScore W2034951351C170286685 @default.
• W2034951351 hasConceptScore W2034951351C203014093 @default.
• W2034951351 hasConceptScore W2034951351C2775915377 @default.
• W2034951351 hasConceptScore W2034951351C2776912625 @default.
• W2034951351 hasConceptScore W2034951351C2777058396 @default.
• W2034951351 hasConceptScore W2034951351C2778453870 @default.
• W2034951351 hasConceptScore W2034951351C2779134260 @default.
• W2034951351 hasConceptScore W2034951351C2779912601 @default.
• W2034951351 hasConceptScore W2034951351C2781205201 @default.
• W2034951351 hasConceptScore W2034951351C535046627 @default.
• W2034951351 hasConceptScore W2034951351C542903549 @default.
• W2034951351 hasConceptScore W2034951351C71924100 @default.
• W2034951351 hasIssue "2" @default.
• W2034951351 hasLocation W20349513511 @default.
• W2034951351 hasLocation W20349513512 @default.
• W2034951351 hasLocation W20349513513 @default.
• W2034951351 hasLocation W20349513514 @default.
• W2034951351 hasOpenAccess W2034951351 @default.
• W2034951351 hasPrimaryLocation W20349513511 @default.
• W2034951351 hasRelatedWork W1508090369 @default.
• W2034951351 hasRelatedWork W2030251794 @default.
• W2034951351 hasRelatedWork W2174957077 @default.
• W2034951351 hasRelatedWork W2559271265 @default.
• W2034951351 hasRelatedWork W2731175524 @default.
• W2034951351 hasRelatedWork W4214897776 @default.
• W2034951351 hasRelatedWork W4224250046 @default.
• W2034951351 hasRelatedWork W4229034713 @default.
• W2034951351 hasRelatedWork W4285613832 @default.
• W2034951351 hasRelatedWork W4377107885 @default.
• W2034951351 hasVolume "6" @default.
• W2034951351 isParatext "false" @default.
• W2034951351 isRetracted "false" @default.
• W2034951351 magId "2034951351" @default.

• next