FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034954321> ?p ?o ?g. }

• W2034954321 endingPage "656" @default.
• W2034954321 startingPage "647" @default.
• W2034954321 abstract "Mobilization and translation of mRNAs, two important events believed to involve stress granules (SGs), in neurons are important for their survival and activities. However, the formation and disassembly of SGs in neurons remains unclear. By using an arsenite-induced neuronal stress model of rat primary spinal cord neuron cultures, we demonstrate the formation of SGs that contain common SG components and RNAs in both stressed neuronal cell bodies and their neurites. By employing small interfering RNA (siRNA) knockdown, we discovered that dynein motor subunit localizes in SG, and is important for SG assembly in neurons. Under stress, dynein motor subunit also facilitates translational repression and enhances the formation and integrity of SG in neurons. By blocking the energy source of dynein motor, both the formation and disassembly of SG are attenuated. These findings demonstrate, for the first time, that dynein motor complex plays a critical role in the dynamics of neuronal SGs, as well as translation of certain mRNAs." @default.
• W2034954321 created "2016-06-24" @default.
• W2034954321 creator A5024957372 @default.
• W2034954321 creator A5034365665 @default.
• W2034954321 creator A5089399092 @default.
• W2034954321 date "2009-03-01" @default.
• W2034954321 modified "2023-10-18" @default.
• W2034954321 title "Dynein motor contributes to stress granule dynamics in primary neurons" @default.
• W2034954321 cites W1980936109 @default.
• W2034954321 cites W1983365254 @default.
• W2034954321 cites W1989177998 @default.
• W2034954321 cites W1989390455 @default.
• W2034954321 cites W1990958605 @default.
• W2034954321 cites W2011467252 @default.
• W2034954321 cites W2012090339 @default.
• W2034954321 cites W2017794334 @default.
• W2034954321 cites W2021058325 @default.
• W2034954321 cites W2028304454 @default.
• W2034954321 cites W2049311171 @default.
• W2034954321 cites W2052137498 @default.
• W2034954321 cites W2060115989 @default.
• W2034954321 cites W2060787288 @default.
• W2034954321 cites W2062564388 @default.
• W2034954321 cites W2064140502 @default.
• W2034954321 cites W2082229119 @default.
• W2034954321 cites W2084407987 @default.
• W2034954321 cites W2093117575 @default.
• W2034954321 cites W2096821445 @default.
• W2034954321 cites W2097843267 @default.
• W2034954321 cites W2102270239 @default.
• W2034954321 cites W2102883851 @default.
• W2034954321 cites W2109383336 @default.
• W2034954321 cites W2114357275 @default.
• W2034954321 cites W2136234317 @default.
• W2034954321 cites W2149541702 @default.
• W2034954321 cites W2151665739 @default.
• W2034954321 cites W2160226734 @default.
• W2034954321 cites W2169158245 @default.
• W2034954321 cites W4256110274 @default.
• W2034954321 doi "https://doi.org/10.1016/j.neuroscience.2008.12.053" @default.
• W2034954321 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2650738" @default.
• W2034954321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19171178" @default.
• W2034954321 hasPublicationYear "2009" @default.
• W2034954321 type Work @default.
• W2034954321 sameAs 2034954321 @default.
• W2034954321 citedByCount "60" @default.
• W2034954321 countsByYear W20349543212012 @default.
• W2034954321 countsByYear W20349543212013 @default.
• W2034954321 countsByYear W20349543212014 @default.
• W2034954321 countsByYear W20349543212015 @default.
• W2034954321 countsByYear W20349543212016 @default.
• W2034954321 countsByYear W20349543212017 @default.
• W2034954321 countsByYear W20349543212018 @default.
• W2034954321 countsByYear W20349543212019 @default.
• W2034954321 countsByYear W20349543212020 @default.
• W2034954321 countsByYear W20349543212021 @default.
• W2034954321 countsByYear W20349543212022 @default.
• W2034954321 countsByYear W20349543212023 @default.
• W2034954321 crossrefType "journal-article" @default.
• W2034954321 hasAuthorship W2034954321A5024957372 @default.
• W2034954321 hasAuthorship W2034954321A5034365665 @default.
• W2034954321 hasAuthorship W2034954321A5089399092 @default.
• W2034954321 hasBestOaLocation W20349543212 @default.
• W2034954321 hasConcept C104292427 @default.
• W2034954321 hasConcept C104317684 @default.
• W2034954321 hasConcept C105580179 @default.
• W2034954321 hasConcept C106987784 @default.
• W2034954321 hasConcept C113246987 @default.
• W2034954321 hasConcept C117838200 @default.
• W2034954321 hasConcept C149364088 @default.
• W2034954321 hasConcept C169760540 @default.
• W2034954321 hasConcept C173396325 @default.
• W2034954321 hasConcept C202751555 @default.
• W2034954321 hasConcept C20418707 @default.
• W2034954321 hasConcept C2776752467 @default.
• W2034954321 hasConcept C2780775167 @default.
• W2034954321 hasConcept C54355233 @default.
• W2034954321 hasConcept C81885089 @default.
• W2034954321 hasConcept C86803240 @default.
• W2034954321 hasConcept C95444343 @default.
• W2034954321 hasConceptScore W2034954321C104292427 @default.
• W2034954321 hasConceptScore W2034954321C104317684 @default.
• W2034954321 hasConceptScore W2034954321C105580179 @default.
• W2034954321 hasConceptScore W2034954321C106987784 @default.
• W2034954321 hasConceptScore W2034954321C113246987 @default.
• W2034954321 hasConceptScore W2034954321C117838200 @default.
• W2034954321 hasConceptScore W2034954321C149364088 @default.
• W2034954321 hasConceptScore W2034954321C169760540 @default.
• W2034954321 hasConceptScore W2034954321C173396325 @default.
• W2034954321 hasConceptScore W2034954321C202751555 @default.
• W2034954321 hasConceptScore W2034954321C20418707 @default.
• W2034954321 hasConceptScore W2034954321C2776752467 @default.
• W2034954321 hasConceptScore W2034954321C2780775167 @default.
• W2034954321 hasConceptScore W2034954321C54355233 @default.
• W2034954321 hasConceptScore W2034954321C81885089 @default.
• W2034954321 hasConceptScore W2034954321C86803240 @default.
• W2034954321 hasConceptScore W2034954321C95444343 @default.
• W2034954321 hasIssue "2" @default.

• next