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• W2034963983 endingPage "181" @default.
• W2034963983 startingPage "158" @default.
• W2034963983 abstract "Autism Spectrum Disorder (ASD) symptoms have been hypothesized to result from altered brain connectivity. The 'disconnectivity' hypothesis has been used to explain characteristic impairments in socio-emotional function, observed clinically in ASD. Here, we review the evidence for impaired white matter connectivity as a neural substrate for socio-emotional dysfunction in ASD. A review of diffusion tensor imaging (DTI) studies, and focused discussion of relevant post-mortem, structural, and functional neuroimaging studies, is provided.Studies were identified using a sensitive search strategy in MEDLINE, Embase and PsycINFO article databases using the OvidSP database interface. Search terms included database subject headings for the concepts of pervasive developmental disorders, and DTI. Seventy-two published DTI studies examining white matter microstructure in ASD were reviewed. A comprehensive discussion of DTI studies that examined white matter tracts linking socio-emotional structures is presented.Several DTI studies reported microstructural differences indicative of developmental alterations in white matter organization, and potentially myelination, in ASD. Altered structure within long-range white matter tracts linking socio-emotional processing regions was implicated. While alterations of the uncinate fasciculus and frontal and temporal thalamic projections have been associated with social symptoms in ASD, few studies examined association of tract microstructure with core impairment in this disorder.The uncinate fasciculus and frontal and temporal thalamic projections mediate limbic connectivity and integrate structures responsible for complex socio-emotional functioning. Impaired development of limbic connectivity may represent one neural substrate contributing to ASD social impairments. Future efforts to further elucidate the nature of atypical white matter development, and its relationship to core symptoms, may offer new insights into etiological mechanisms contributing to ASD impairments and uncover novel opportunities for targeted intervention." @default.
• W2034963983 created "2016-06-24" @default.
• W2034963983 creator A5010073100 @default.
• W2034963983 creator A5048893079 @default.
• W2034963983 date "2015-01-01" @default.
• W2034963983 modified "2023-10-03" @default.
• W2034963983 title "Altered white matter connectivity as a neural substrate for social impairment in Autism Spectrum Disorder" @default.
• W2034963983 cites W1530546319 @default.
• W2034963983 cites W1579913460 @default.
• W2034963983 cites W1774330082 @default.
• W2034963983 cites W1884438802 @default.
• W2034963983 cites W1923605364 @default.
• W2034963983 cites W1965018875 @default.
• W2034963983 cites W1969576961 @default.
• W2034963983 cites W1969700144 @default.
• W2034963983 cites W1973127790 @default.
• W2034963983 cites W1977610079 @default.
• W2034963983 cites W1978967977 @default.
• W2034963983 cites W1981316009 @default.
• W2034963983 cites W1983572841 @default.
• W2034963983 cites W1987858724 @default.
• W2034963983 cites W1992891207 @default.
• W2034963983 cites W1993636237 @default.
• W2034963983 cites W1994461253 @default.
• W2034963983 cites W1995647101 @default.
• W2034963983 cites W1995661277 @default.
• W2034963983 cites W2000454722 @default.
• W2034963983 cites W2003064434 @default.
• W2034963983 cites W2003370843 @default.
• W2034963983 cites W2004046545 @default.
• W2034963983 cites W2004265420 @default.
• W2034963983 cites W2005342778 @default.
• W2034963983 cites W2005387911 @default.
• W2034963983 cites W2006353938 @default.
• W2034963983 cites W2009349015 @default.
• W2034963983 cites W2010164205 @default.
• W2034963983 cites W2010538600 @default.
• W2034963983 cites W2010960204 @default.
• W2034963983 cites W2011157767 @default.
• W2034963983 cites W2013995615 @default.
• W2034963983 cites W2018345741 @default.
• W2034963983 cites W2020960495 @default.
• W2034963983 cites W2022043519 @default.
• W2034963983 cites W2022236299 @default.
• W2034963983 cites W2022530159 @default.
• W2034963983 cites W2023386088 @default.
• W2034963983 cites W2023404034 @default.
• W2034963983 cites W2025180319 @default.
• W2034963983 cites W2025551837 @default.
• W2034963983 cites W2030059540 @default.
• W2034963983 cites W2033216229 @default.
• W2034963983 cites W2034454761 @default.
• W2034963983 cites W2035135896 @default.
• W2034963983 cites W2035541936 @default.
• W2034963983 cites W2037537703 @default.
• W2034963983 cites W2038568172 @default.
• W2034963983 cites W2039929057 @default.
• W2034963983 cites W2040082820 @default.
• W2034963983 cites W2042285184 @default.
• W2034963983 cites W2042648869 @default.
• W2034963983 cites W2043038397 @default.
• W2034963983 cites W2043038916 @default.
• W2034963983 cites W2045363365 @default.
• W2034963983 cites W2045376319 @default.
• W2034963983 cites W2045498423 @default.
• W2034963983 cites W2046265374 @default.
• W2034963983 cites W2047143817 @default.
• W2034963983 cites W2047152236 @default.
• W2034963983 cites W2049168632 @default.
• W2034963983 cites W2049784414 @default.
• W2034963983 cites W2050363810 @default.
• W2034963983 cites W2052457468 @default.
• W2034963983 cites W2053258586 @default.
• W2034963983 cites W2054390925 @default.
• W2034963983 cites W2054875016 @default.
• W2034963983 cites W2055103624 @default.
• W2034963983 cites W2055825410 @default.
• W2034963983 cites W2055866745 @default.
• W2034963983 cites W2056334380 @default.
• W2034963983 cites W2061696649 @default.
• W2034963983 cites W2063001897 @default.
• W2034963983 cites W2063167566 @default.
• W2034963983 cites W2064055424 @default.
• W2034963983 cites W2065827336 @default.
• W2034963983 cites W2068285943 @default.
• W2034963983 cites W2068943457 @default.
• W2034963983 cites W2069565653 @default.
• W2034963983 cites W2070292918 @default.
• W2034963983 cites W2073699108 @default.
• W2034963983 cites W2073708086 @default.
• W2034963983 cites W2074457840 @default.
• W2034963983 cites W2074976205 @default.
• W2034963983 cites W2078195020 @default.
• W2034963983 cites W2080605824 @default.
• W2034963983 cites W2080810355 @default.
• W2034963983 cites W2081771004 @default.
• W2034963983 cites W2082630431 @default.
• W2034963983 cites W2084222045 @default.

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