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• W2034971091 abstract "Piperacillin/Tazobactam is a time-dependent antimicrobial combination (beta-lactam/beta-lactamase inhibitor) commonly used in the treatment of severe Gram-negative infections. The optimisation of its time-dependent bactericidal activity via continuous infusion could improve clinical outcomes. Several studies have been realized on the relevance of a continuous infusion, but, to date, no definitive position can be adopted on the matter and a well-designed randomized controlled trial is warranted. In other articles, continuous infusion regimens are also more cost efficient. This article is an update, including the most recent trials about this subject." @default.
• W2034971091 created "2016-06-24" @default.
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• W2034971091 date "2014-05-01" @default.
• W2034971091 modified "2023-10-06" @default.
• W2034971091 title "Continuous infusion of piperacillin/tazobactam in patients with severe infections: A possible pharmacokinetic optimisation?" @default.
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• W2034971091 doi "https://doi.org/10.1016/j.pharma.2013.12.006" @default.
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