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- W2034974560 abstract "La esclerosis múltiple es una enfermedad inflamatoria de base autoinmune del SNC. Se manifiesta en pacientes jóvenes, con sintomatología neurológica variable, en general de instauración subaguda. La neuritis óptica, la mielitis incompleta y un síndrome de tronco cerebral son formas de comienzo típicas. La RM es una técnica muy útil para el diagnóstico y manejo de la EM en base a criterios radiológicos bien definidos. Permite la demostración de diseminación en espacio y tiempo de las lesiones desmielinizantes, ha logrado modificar igualmente los criterios de diagnóstico clínico clásicos. El LCR nos ayuda a confirmar el diagnóstico de EM al demostrar síntesis intratecal y presencia de bandas oligoclonales de IgG. Los potenciales evocados nos permiten detectar alteraciones en las distintas vías nerviosas tras la realización de un estímulo sensorial o sensitivo. Esto nos permitiría detectar lesiones silentes en el SNC. El diagnóstico diferencial de la EM se realiza excluyendo una serie de enfermedades que pueden presentar características similares por la variedad de manifestaciones clínicas de la EM. Multiple sclerosis (MS) is an inflammatory disease of CNS having an autoimmune etiology. It appears in young patients. The neurologic symptomatology is variable, usually with sub-acute presentation. The most common onset forms are: optic neuritis, incomplete myelitis and brainstem syndrome. Magnetic resonance imaging (MRI), using well-defined radiological criteria, is a useful diagnosis tool: it provides evidence for dissemination in space and time of demyelinating lesions and has modified classical diagnostic criteria. Cerebral spinal fluid (CSF) is useful in diagnostic confirmation (confirms the intrathecal synthesis of IgG and detects a pattern of oligoclonal bands). Evoked potentials detect nerve conduction disturbances and are useful in identifying clinically silent lesions. Differential diagnosis of MS must be performed with those conditions that may be confused with MS." @default.
- W2034974560 created "2016-06-24" @default.
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- W2034974560 date "2015-04-01" @default.
- W2034974560 modified "2023-09-30" @default.
- W2034974560 title "Protocolo diagnóstico del paciente con sospecha de enfermedad desmielinizante" @default.
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- W2034974560 doi "https://doi.org/10.1016/j.med.2015.04.005" @default.
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