FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034976767> ?p ?o ?g. }

• W2034976767 endingPage "147" @default.
• W2034976767 startingPage "141" @default.
• W2034976767 abstract "Chronic alcohol consumption is a well-known risk factor for hepatic injury, and mitochondrial damage plays a significant role in this process. Nitric oxide (NO) is an important modulator of mitochondrial function and is known to inhibit mitochondrial respiration. However, the impact of chronic alcohol consumption on NO-dependent control of liver mitochondrial function is unknown. This study examines the effect of alcohol exposure on liver mitochondria in a rat model and explores the interaction of NO and mitochondrial respiration in this context. Mitochondria were isolated from the liver of both control and ethanol-fed rats after 5 to 6 weeks of alcohol consumption. Mitochondria isolated from ethanol-treated rats showed a significant decrease in state 3 respiration and respiratory control ratio that was accompanied by an increased sensitivity to NO-dependent inhibition of respiration. In conclusion, we show that chronic alcohol consumption leads to increased sensitivity to the inhibition of respiration by NO. We propose that this results in a greater vulnerability to hypoxia and the development of alcohol-induced hepatotoxicity." @default.
• W2034976767 created "2016-06-24" @default.
• W2034976767 creator A5047734216 @default.
• W2034976767 creator A5060599255 @default.
• W2034976767 creator A5062506120 @default.
• W2034976767 creator A5079704367 @default.
• W2034976767 creator A5085442790 @default.
• W2034976767 creator A5091511563 @default.
• W2034976767 date "2003-07-01" @default.
• W2034976767 modified "2023-10-17" @default.
• W2034976767 title "Chronic alcohol consumption increases the sensitivity of rat liver mitochondrial respiration to inhibition by nitric oxide" @default.
• W2034976767 cites W1182297257 @default.
• W2034976767 cites W1528220495 @default.
• W2034976767 cites W1547863599 @default.
• W2034976767 cites W18874106 @default.
• W2034976767 cites W1972368504 @default.
• W2034976767 cites W1976505903 @default.
• W2034976767 cites W1981520518 @default.
• W2034976767 cites W1983372621 @default.
• W2034976767 cites W1991259391 @default.
• W2034976767 cites W1999098395 @default.
• W2034976767 cites W2001489029 @default.
• W2034976767 cites W2003761032 @default.
• W2034976767 cites W2004266373 @default.
• W2034976767 cites W2009279488 @default.
• W2034976767 cites W2018205667 @default.
• W2034976767 cites W2025878987 @default.
• W2034976767 cites W2037504375 @default.
• W2034976767 cites W2041124801 @default.
• W2034976767 cites W2056966959 @default.
• W2034976767 cites W2060156800 @default.
• W2034976767 cites W2066050507 @default.
• W2034976767 cites W2071527455 @default.
• W2034976767 cites W2071795040 @default.
• W2034976767 cites W2073180738 @default.
• W2034976767 cites W2074155059 @default.
• W2034976767 cites W2080128777 @default.
• W2034976767 cites W2083875409 @default.
• W2034976767 cites W2084621494 @default.
• W2034976767 cites W2085001324 @default.
• W2034976767 cites W2087462122 @default.
• W2034976767 cites W2104841128 @default.
• W2034976767 cites W2108789866 @default.
• W2034976767 cites W2126714905 @default.
• W2034976767 cites W2133362207 @default.
• W2034976767 cites W2141026309 @default.
• W2034976767 cites W2144970617 @default.
• W2034976767 cites W2152746956 @default.
• W2034976767 cites W2155557800 @default.
• W2034976767 cites W2163278516 @default.
• W2034976767 cites W2275889189 @default.
• W2034976767 cites W2342792498 @default.
• W2034976767 cites W2417308391 @default.
• W2034976767 cites W2729188489 @default.
• W2034976767 cites W962061814 @default.
• W2034976767 doi "https://doi.org/10.1053/jhep.2003.50293" @default.
• W2034976767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12829996" @default.
• W2034976767 hasPublicationYear "2003" @default.
• W2034976767 type Work @default.
• W2034976767 sameAs 2034976767 @default.
• W2034976767 citedByCount "56" @default.
• W2034976767 countsByYear W20349767672012 @default.
• W2034976767 countsByYear W20349767672013 @default.
• W2034976767 countsByYear W20349767672014 @default.
• W2034976767 countsByYear W20349767672015 @default.
• W2034976767 countsByYear W20349767672016 @default.
• W2034976767 countsByYear W20349767672017 @default.
• W2034976767 countsByYear W20349767672019 @default.
• W2034976767 countsByYear W20349767672022 @default.
• W2034976767 countsByYear W20349767672023 @default.
• W2034976767 crossrefType "journal-article" @default.
• W2034976767 hasAuthorship W2034976767A5047734216 @default.
• W2034976767 hasAuthorship W2034976767A5060599255 @default.
• W2034976767 hasAuthorship W2034976767A5062506120 @default.
• W2034976767 hasAuthorship W2034976767A5079704367 @default.
• W2034976767 hasAuthorship W2034976767A5085442790 @default.
• W2034976767 hasAuthorship W2034976767A5091511563 @default.
• W2034976767 hasBestOaLocation W20349767671 @default.
• W2034976767 hasConcept C105702510 @default.
• W2034976767 hasConcept C126322002 @default.
• W2034976767 hasConcept C134018914 @default.
• W2034976767 hasConcept C151730666 @default.
• W2034976767 hasConcept C182215343 @default.
• W2034976767 hasConcept C185592680 @default.
• W2034976767 hasConcept C2779343474 @default.
• W2034976767 hasConcept C2780161600 @default.
• W2034976767 hasConcept C2781066024 @default.
• W2034976767 hasConcept C28859421 @default.
• W2034976767 hasConcept C519581460 @default.
• W2034976767 hasConcept C55493867 @default.
• W2034976767 hasConcept C66517615 @default.
• W2034976767 hasConcept C71924100 @default.
• W2034976767 hasConcept C86803240 @default.
• W2034976767 hasConceptScore W2034976767C105702510 @default.
• W2034976767 hasConceptScore W2034976767C126322002 @default.
• W2034976767 hasConceptScore W2034976767C134018914 @default.
• W2034976767 hasConceptScore W2034976767C151730666 @default.
• W2034976767 hasConceptScore W2034976767C182215343 @default.

• next