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• W2034982705 abstract "How do T cells find their way to the epidermis? Ever since a special relationship between T cells and epidermis was first postulated, it has been assumed that T-cell trafficking through skin occurs as a matter of course, and that the exaggeration of this process may explain the histopathologic features of many diseases characterized by T-cell infiltration of skin.^1,2However, the molecular basis for the affinity of T cells (and, indeed, of other bone marrow-derived leukocytes) for epidermis has remained obscure. Recently, several groups have contributed an important piece to the T cell-epidermis puzzle by focusing on the role of a group of glycoproteins collectively called adhesion molecules.^3-6Many of these molecules are members of the integrin family of proteins (based on molecular relationships), which, in turn, are thought to belong to the immunoglobulin gene superfamily.⁷The integrins are a heterogeneous group of proteins that appear to" @default.
• W2034982705 created "2016-06-24" @default.
• W2034982705 creator A5091128223 @default.
• W2034982705 date "1989-10-01" @default.
• W2034982705 modified "2023-10-03" @default.
• W2034982705 title "Mechanisms of Cutaneous Inflammation" @default.
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• W2034982705 doi "https://doi.org/10.1001/archderm.1989.01670220102017" @default.
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