FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034983218> ?p ?o ?g. }

• W2034983218 endingPage "656" @default.
• W2034983218 startingPage "651" @default.
• W2034983218 abstract "Angiotensin II (AngII) is a hormone with long‑established cardiovascular actions. Previous studies have revealed an additional role for AngII in the regulation of cutaneous wound healing. To evaluate the association between AngII and abnormal pigmentation of cutaneous wound healing, the present study used human melanocytes to investigate the effects of AngII on melanogenesis, and to elucidate the possible underlying mechanisms. Primary culture melanocytes were treated with AngII either alone or in combination with an AngII type 1 (AT1) receptor antagonist, losartan (LOS). The melanin content and tyrosinase activity were measured and reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) and western blotting were performed to assess the proteins involved in melanogenesis and the AT1 receptor. AngII regulated the mRNA expression of AT1 in the melanocytes. The melanin content and tyrosinase activity increased in response to treatment with AngII in a concentration‑dependent manner. RT‑qPCR and western blotting revealed that the AT1 receptor antagonist, LOS, eliminated this effect. These results provide a novel insight into the role of AngII and its associated signaling in melanogenesis." @default.
• W2034983218 created "2016-06-24" @default.
• W2034983218 creator A5011011059 @default.
• W2034983218 creator A5032352505 @default.
• W2034983218 creator A5046778284 @default.
• W2034983218 creator A5021561271 @default.
• W2034983218 creator A5075182330 @default.
• W2034983218 date "2012-03-05" @default.
• W2034983218 modified "2023-10-10" @default.
• W2034983218 title "Angiotensin II promotes melanogenesis via angiotensin II type 1 receptors in human melanocytes" @default.
• W2034983218 cites W142258434 @default.
• W2034983218 cites W1966454263 @default.
• W2034983218 cites W1972557284 @default.
• W2034983218 cites W1982852026 @default.
• W2034983218 cites W1985107143 @default.
• W2034983218 cites W1990893042 @default.
• W2034983218 cites W1997727747 @default.
• W2034983218 cites W2017658686 @default.
• W2034983218 cites W2036487040 @default.
• W2034983218 cites W2042658249 @default.
• W2034983218 cites W2042702834 @default.
• W2034983218 cites W2045202298 @default.
• W2034983218 cites W2050167194 @default.
• W2034983218 cites W2060575303 @default.
• W2034983218 cites W2067946831 @default.
• W2034983218 cites W2069912425 @default.
• W2034983218 cites W2099326699 @default.
• W2034983218 cites W2115609068 @default.
• W2034983218 cites W2127083467 @default.
• W2034983218 cites W2138745567 @default.
• W2034983218 cites W2139258437 @default.
• W2034983218 cites W2146627961 @default.
• W2034983218 cites W2150664442 @default.
• W2034983218 cites W2159464213 @default.
• W2034983218 cites W2325727928 @default.
• W2034983218 cites W4293247451 @default.
• W2034983218 doi "https://doi.org/10.3892/mmr.2015.3438" @default.
• W2034983218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25760379" @default.
• W2034983218 hasPublicationYear "2012" @default.
• W2034983218 type Work @default.
• W2034983218 sameAs 2034983218 @default.
• W2034983218 citedByCount "6" @default.
• W2034983218 countsByYear W20349832182018 @default.
• W2034983218 countsByYear W20349832182019 @default.
• W2034983218 countsByYear W20349832182020 @default.
• W2034983218 countsByYear W20349832182021 @default.
• W2034983218 crossrefType "journal-article" @default.
• W2034983218 hasAuthorship W2034983218A5011011059 @default.
• W2034983218 hasAuthorship W2034983218A5021561271 @default.
• W2034983218 hasAuthorship W2034983218A5032352505 @default.
• W2034983218 hasAuthorship W2034983218A5046778284 @default.
• W2034983218 hasAuthorship W2034983218A5075182330 @default.
• W2034983218 hasBestOaLocation W20349832181 @default.
• W2034983218 hasConcept C104317684 @default.
• W2034983218 hasConcept C104849204 @default.
• W2034983218 hasConcept C107538193 @default.
• W2034983218 hasConcept C123915805 @default.
• W2034983218 hasConcept C126322002 @default.
• W2034983218 hasConcept C134018914 @default.
• W2034983218 hasConcept C170493617 @default.
• W2034983218 hasConcept C181199279 @default.
• W2034983218 hasConcept C185592680 @default.
• W2034983218 hasConcept C198710026 @default.
• W2034983218 hasConcept C2776885963 @default.
• W2034983218 hasConcept C2780288358 @default.
• W2034983218 hasConcept C2908929049 @default.
• W2034983218 hasConcept C55493867 @default.
• W2034983218 hasConcept C71924100 @default.
• W2034983218 hasConcept C84393581 @default.
• W2034983218 hasConcept C85265743 @default.
• W2034983218 hasConcept C86803240 @default.
• W2034983218 hasConcept C87554066 @default.
• W2034983218 hasConcept C98274493 @default.
• W2034983218 hasConceptScore W2034983218C104317684 @default.
• W2034983218 hasConceptScore W2034983218C104849204 @default.
• W2034983218 hasConceptScore W2034983218C107538193 @default.
• W2034983218 hasConceptScore W2034983218C123915805 @default.
• W2034983218 hasConceptScore W2034983218C126322002 @default.
• W2034983218 hasConceptScore W2034983218C134018914 @default.
• W2034983218 hasConceptScore W2034983218C170493617 @default.
• W2034983218 hasConceptScore W2034983218C181199279 @default.
• W2034983218 hasConceptScore W2034983218C185592680 @default.
• W2034983218 hasConceptScore W2034983218C198710026 @default.
• W2034983218 hasConceptScore W2034983218C2776885963 @default.
• W2034983218 hasConceptScore W2034983218C2780288358 @default.
• W2034983218 hasConceptScore W2034983218C2908929049 @default.
• W2034983218 hasConceptScore W2034983218C55493867 @default.
• W2034983218 hasConceptScore W2034983218C71924100 @default.
• W2034983218 hasConceptScore W2034983218C84393581 @default.
• W2034983218 hasConceptScore W2034983218C85265743 @default.
• W2034983218 hasConceptScore W2034983218C86803240 @default.
• W2034983218 hasConceptScore W2034983218C87554066 @default.
• W2034983218 hasConceptScore W2034983218C98274493 @default.
• W2034983218 hasIssue "1" @default.
• W2034983218 hasLocation W20349832181 @default.
• W2034983218 hasLocation W20349832182 @default.
• W2034983218 hasOpenAccess W2034983218 @default.
• W2034983218 hasPrimaryLocation W20349832181 @default.

• next