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- W2034983257 abstract "Abstract The dual soleus-gastrocnemius (S-G) preparation in the cat, with each muscle working separately but simultaneously in isometric mode under bursts of electrical stimuli to the nerve trunk, has been perfused at constant rate with tropine-p-tolylacetate methiodide (I). With each muscle tissue, variable elements of strong response blockade and weak response augmentation are observed as a function of ester I infusate concentration and frequency of pulses in the stimulus burst (range 25–100 Hz). In response blockade at high infusion levels of I, results with the dual S-G preparation afford only one sizable contrast with corresponding effects seen in blockade of individual, isolated S and G tissues: the S muscle operating in the dual S-G complex requires I blocking concentrations (ca. 1.0 × 10−2 m ) one to three orders of magnitude greater than those needed to effect strong blockade in the isolated S preparation (1.0 × 10−5 to 5.0 × 10−4 m ). This contrast is interpreted in terms of blood flow partition in the dual S-G arterial supply system. Further, in response augmentation from the dual S-G tissues at I infusate levels in the range 1.0 × 10−4 to 1.0 × 10−8 m , the S and G muscles show separate dependencies of effect on stimulus frequency, and a relatively greater magnitude of G responses to ester-stimulus combinations producing augmentation." @default.
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- W2034983257 date "1971-01-01" @default.
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- W2034983257 title "Blockade in simultaneously perfused soleus and gastrocnemius muscles in the cat" @default.
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- W2034983257 doi "https://doi.org/10.1016/0041-008x(71)90322-x" @default.
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