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• W2034984029 abstract "Analogues of L-glutamine were designed and synthesized to test a hydrogen-bond hypothesis between ligand and neutral amino acid transporter ASCT2. The key design feature contains a substituted phenyl ring on the amide nitrogen that contains electron withdrawing and electron donating groups that alter the pKa of the amide NH. Through this study a preliminary binding site map has been developed, and a potent commercially available competitive inhibitor of the ASCT2 transporter has been identified." @default.
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• W2034984029 date "2005-02-01" @default.
• W2034984029 modified "2023-10-06" @default.
• W2034984029 title "Nγ-Aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site" @default.
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• W2034984029 doi "https://doi.org/10.1016/j.bmc.2004.11.028" @default.
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