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• W2034985627 startingPage "3976" @default.
• W2034985627 abstract "4″,6″-Didehydro-cADPcR (3), an unsaturated carbocyclic ribose analog of a Ca2+-mobilizing second messenger cyclic ADP-ribose (cADPR), was designed and successfully synthesized using a key intramolecular condensation reaction forming the 18-membered pyrophosphate ring structure with a S-phenyl phosphorothioate-type substrate. Biological evaluation showed that 4″,6″-didehydro-cADPcR is a potent Ca2+-mobilizing agent in T cells." @default.
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• W2034985627 date "2008-06-01" @default.
• W2034985627 modified "2023-10-17" @default.
• W2034985627 title "Design and synthesis of 4″,6″-unsaturated cyclic ADP-carbocyclic ribose as a Ca2+-mobilizing agent" @default.
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• W2034985627 doi "https://doi.org/10.1016/j.tetlet.2008.04.100" @default.
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