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• W2034990414 abstract "Arthritis & RheumatismVolume 36, Issue 9 p. 1335-1336 LetterFree to Read The regulatory role of doxycycline/tetracycline in collagenolytic activity and tissue destruction in joint diseases: comment on the article by Yu et al A. Lauhio MD, A. Lauhio MD University of HelsinkiSearch for more papers by this authorT. Sorsa DDS, PhD, T. Sorsa DDS, PhD University of HelsinkiSearch for more papers by this authorO. Lindy MD, O. Lindy MD University Central HospitalSearch for more papers by this authorK. Suomalainen DDS, K. Suomalainen DDS Aurora Hospital, Helsinki, FinlandSearch for more papers by this authorH. Saari MD, PhD, H. Saari MD, PhD State University of New York at Stony Brook, Stony Brook, NYSearch for more papers by this authorL. M. Golub DMD, MSc, L. M. Golub DMD, MSc State University of New York at Stony Brook, Stony Brook, NYSearch for more papers by this authorY. T. Konttinen MD, PhD, Y. T. Konttinen MD, PhD State University of New York at Stony Brook, Stony Brook, NYSearch for more papers by this author A. Lauhio MD, A. Lauhio MD University of HelsinkiSearch for more papers by this authorT. Sorsa DDS, PhD, T. Sorsa DDS, PhD University of HelsinkiSearch for more papers by this authorO. Lindy MD, O. Lindy MD University Central HospitalSearch for more papers by this authorK. Suomalainen DDS, K. Suomalainen DDS Aurora Hospital, Helsinki, FinlandSearch for more papers by this authorH. Saari MD, PhD, H. Saari MD, PhD State University of New York at Stony Brook, Stony Brook, NYSearch for more papers by this authorL. M. Golub DMD, MSc, L. M. Golub DMD, MSc State University of New York at Stony Brook, Stony Brook, NYSearch for more papers by this authorY. T. Konttinen MD, PhD, Y. T. Konttinen MD, PhD State University of New York at Stony Brook, Stony Brook, NYSearch for more papers by this author First published: September 1993 https://doi.org/10.1002/art.1780360924Citations: 11AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL No abstract is available for this article. Reference 1 Yu LP Jr, Smith GN Jr, Brandt KD, Myers SL, O'Connor BL, Brandt DA: Reduction of the severity of canine osteoarthritis by prophylactic treatment with oral doxycycline. Arthritis Rheum 35: 1150– 1159, 1992 2 Suomalainen K, Sorsa T, Golub LM, Ramamurthy NS, Lee HM, Uitto V-J, Saari H, Konttinen YT: Specificity of the anti-collagenase action of tetracyclines: relevance to their antiinflammatory potential. Antimicrob Agents Chemother 36: 227– 229, 1992 3 Weiss SJ: Tissue destruction by neutrophils. N Engl J Med 320: 365– 376, 1989 4 Sorsa T, Saari H, Konttinen YT, Uitto V-J, Lindy S: Human neutrophil collagenase and oxygen derived free radicals. N Engl J Med 321: 327– 328, 1989 5 Konttinen YT, Lindy O, Suomalainen K, Lauhio A, Saari H, Vauhkonen M, Santavirta S, Sorsa T: Substrate specificity and activation mechanisms of collagenase from human rheumatoid synovium. Matrix 11: 395– 403, 1991 6 Lauhio A, Sorsa T, Lindy O, Suomalainen K, Saari H, Golub LM, Konttinen YT: The anticollagenolytic potential of lymecycline in the long-term treatment of reactive arthritis. Arthritis Rheum 35: 195– 198, 1992 7 Lauhio A, Nordström D, Sorsa T, Rose S, Lindy O, Golub LM, Konttinen YT: Long-term treatment of reactive arthritis with tetracycline, Prog Rheumatol (in press) 8 Ramamurthy NS, Greenwald RA, Vernillo A, Lee H-M, Golub LM, Rifkin B: Oxygen radicals activate and tetracyclines inhibit rat osteoblast collagenase (abstract). J Dent Res 71: 757, 1992 9 Lauhio A, Leirisalo-Repo M, Lähdevirta J, Saikku P, Repo H: Double-blind, placebo-controlled study of three-month treatment with lymecycline in reactive arthritis, with special reference to Chlamydia arthritis. Arthritis Rheum 34: 6– 14, 1991 10 Sorsa T, Lindy O, Konttinen YT, Suomalainen K, Ingman T, Saari H, Halinen S, Lee H-M, Golub LM, Hall J, Simon S: Doxycycline protects serum alpha-1-antitrypsin from human neutrophil collagenase. Antimicrob Agents Chemother 37: 592– 594, 1993 11 Stricklin G, Hoidart J: Oxidant-mediated inactivation of TIMP. Matrix 12 (suppl 1): 325– 326, 1992 12 Blackburn WD Jr, Loose LD, Heck LW, Chatham WW: Tenidap, in contrast to several available nonsteroidal antiinflammatory drugs, potently inhibits the release of activated neutrophil collagenase. Arthritis Rheum 34: 211– 216, 1991 13 Ramamurthy N, Leung M, Moak S, Greenwald R, Golub L: CMT/NSAID combination increases bone CMT uptake and inhibits bone resorption (abstract). J Dent Res 72: 333, 1993 14 Greenwald RA, Ramamurthy NS, Moak SA, Golub LM: Metalloproteinase activity and radiologic severity of adjuvant arthritis: synergistic beneficial effects of tenidap and 4-dedimethylamine tetracycline (abstract). Arthritis Rheum 35 (suppl 9): S131, 1992 Citing Literature Volume36, Issue9September 1993Pages 1335-1336 ReferencesRelatedInformation" @default.
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