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• W2034991659 abstract "Northern Ireland has the second highest incidence of colorectal cancer in the world. Accurate assessment, by either barium enema or colonoscopy is essential. Both investigations require satisfactory pre-examination bowel preparation. Two prospective audits were carried out at the causeway Trust Hospitals to assess the efficacy, tolerability and side effect profiles of the belowmentioned preparations. The first audit was to compare the standard 400omls of Klean-prep (PEG) to the combined preparation (CP) of 2- sachet picolax plus 2000mls of Klean-prep. A follow-up audit was performed several months later following the introduction of Fleet (PS). As the methodology and protocol were similar, these two studies have been combined for the purpose of this report. 70 patients were recruited over twenty weeks. They were counseled by a pharmacist before randomisation to PEG (25 patients), PS (20 patients) and CP (25 patients). A questionnaire was completed by the patients detailing palability, compliance and side effects experienced on the day of the examination. Compliance was high PEG=27%, CP=96%, PS=95 but most patients had some difficulty taking all the preparations, PED=60%, CP=48%, PS=32%. There were significant side effects experienced by all groups of patients including those who were tolerant of the preparation (PEG=70%, CP=80%, PS=63%) Colonoscopies were performed by a Consultant Surgeon and a Consultant Gastroenterologist who were both blinded to the preparations taken by the patients. Quality of the preparation was graded 1-5 on the basis of visual assessment. It showed similarly satisfactory results (PEG=95%, CP=90%, PS=100%). The results suggest comparable quality of bowel preparation and suitably high compliance amongst patients in all 3 groups, with no significant difference in the side effect profiles. Klean-prep costs £5.76, while Fleet is slightly cheaper at £4.79. The combined preparation costs £3.65. From this audit, we conclude that the combined preparation represents the most cost-effective method without compromise to the patients or endoscopists. Northern Ireland has the second highest incidence of colorectal cancer in the world. Accurate assessment, by either barium enema or colonoscopy is essential. Both investigations require satisfactory pre-examination bowel preparation. Two prospective audits were carried out at the causeway Trust Hospitals to assess the efficacy, tolerability and side effect profiles of the belowmentioned preparations. The first audit was to compare the standard 400omls of Klean-prep (PEG) to the combined preparation (CP) of 2- sachet picolax plus 2000mls of Klean-prep. A follow-up audit was performed several months later following the introduction of Fleet (PS). As the methodology and protocol were similar, these two studies have been combined for the purpose of this report. 70 patients were recruited over twenty weeks. They were counseled by a pharmacist before randomisation to PEG (25 patients), PS (20 patients) and CP (25 patients). A questionnaire was completed by the patients detailing palability, compliance and side effects experienced on the day of the examination. Compliance was high PEG=27%, CP=96%, PS=95 but most patients had some difficulty taking all the preparations, PED=60%, CP=48%, PS=32%. There were significant side effects experienced by all groups of patients including those who were tolerant of the preparation (PEG=70%, CP=80%, PS=63%) Colonoscopies were performed by a Consultant Surgeon and a Consultant Gastroenterologist who were both blinded to the preparations taken by the patients. Quality of the preparation was graded 1-5 on the basis of visual assessment. It showed similarly satisfactory results (PEG=95%, CP=90%, PS=100%). The results suggest comparable quality of bowel preparation and suitably high compliance amongst patients in all 3 groups, with no significant difference in the side effect profiles. Klean-prep costs £5.76, while Fleet is slightly cheaper at £4.79. The combined preparation costs £3.65. From this audit, we conclude that the combined preparation represents the most cost-effective method without compromise to the patients or endoscopists." @default.
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• W2034991659 title "7208 Audit of pre-colonoscopy bowel preparation." @default.
• W2034991659 doi "https://doi.org/10.1016/s0016-5107(00)14879-5" @default.
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