Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034995109> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2034995109 endingPage "627" @default.
- W2034995109 startingPage "619" @default.
- W2034995109 abstract "A kinetic turbidimetric Limuius amebocyte lysate (LAL) assay was used to study the effects of gentamicin, amoxycillin and ciprofloxacin (16 X MIC) upon release of lipopolysaccharide at different stages of a growing Escherichia coli 055:B5:H culture in vitro. In this model a linear correlation was present between the logarithms of colony counts and free LAL activities. Untreated E. coli grew from log values of 4.9 ± 0.15 (low inoculum) and 6.8 ± 0.08 cfu/ml (high inoculum) at t = 0 to 8.9 ± 0.05 and 9.1 ± 0.13 cfu/ml at t = 6 h, respectively. The log values of basal free LAL activities at low and high inoculum sizes were 1.9 ± 0.07 and 3.3 ± 0.14 endotoxin units/ml, increasing 2100- and 69-fold, respectively during a 6-h growth. Amoxycillin-induced lysis was not significantly associated with an increase in free LAL activity. Efficacy of bacterial killing by gentamicin was high, but free LAL activity increased only 3.2- and 7.7-fold at the low and high inoculum experiments, respectively. Ciprofloxacin induced cell filamentation during the experiments. At low and high inoculum conditions exposure to ciprofloxacin induced a 43- and 68-fold increase in free LAL activities, respectively. Our data indicate that (a) LPS is released as long as E. coli remain structurally intact; (b) LPS release is enhanced when bacterial biomass increases; and (c) are taken as evidence against the concept of lysis-correlated LPS release." @default.
- W2034995109 created "2016-06-24" @default.
- W2034995109 creator A5007041034 @default.
- W2034995109 creator A5024513980 @default.
- W2034995109 creator A5038639010 @default.
- W2034995109 creator A5059269948 @default.
- W2034995109 creator A5063978272 @default.
- W2034995109 creator A5066510552 @default.
- W2034995109 date "1992-01-01" @default.
- W2034995109 modified "2023-10-17" @default.
- W2034995109 title "Delayed Antibiotic-Induced Lysis of Escherichia coli in vitro is Correlated with Enhancement of LPS Release" @default.
- W2034995109 cites W1488656886 @default.
- W2034995109 cites W1964073630 @default.
- W2034995109 cites W1979699648 @default.
- W2034995109 cites W1987671137 @default.
- W2034995109 cites W2008102078 @default.
- W2034995109 cites W2010285305 @default.
- W2034995109 cites W2012950894 @default.
- W2034995109 cites W2014781329 @default.
- W2034995109 cites W2017663495 @default.
- W2034995109 cites W2026596500 @default.
- W2034995109 cites W2035849865 @default.
- W2034995109 cites W2048929642 @default.
- W2034995109 cites W2054917172 @default.
- W2034995109 cites W2086967708 @default.
- W2034995109 cites W2118489730 @default.
- W2034995109 cites W2124671956 @default.
- W2034995109 cites W2137176012 @default.
- W2034995109 cites W2146749940 @default.
- W2034995109 cites W2328724909 @default.
- W2034995109 doi "https://doi.org/10.3109/00365549209054648" @default.
- W2034995109 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1465580" @default.
- W2034995109 hasPublicationYear "1992" @default.
- W2034995109 type Work @default.
- W2034995109 sameAs 2034995109 @default.
- W2034995109 citedByCount "53" @default.
- W2034995109 countsByYear W20349951092016 @default.
- W2034995109 countsByYear W20349951092018 @default.
- W2034995109 countsByYear W20349951092019 @default.
- W2034995109 countsByYear W20349951092021 @default.
- W2034995109 crossrefType "journal-article" @default.
- W2034995109 hasAuthorship W2034995109A5007041034 @default.
- W2034995109 hasAuthorship W2034995109A5024513980 @default.
- W2034995109 hasAuthorship W2034995109A5038639010 @default.
- W2034995109 hasAuthorship W2034995109A5059269948 @default.
- W2034995109 hasAuthorship W2034995109A5063978272 @default.
- W2034995109 hasAuthorship W2034995109A5066510552 @default.
- W2034995109 hasConcept C104317684 @default.
- W2034995109 hasConcept C153911025 @default.
- W2034995109 hasConcept C185592680 @default.
- W2034995109 hasConcept C202751555 @default.
- W2034995109 hasConcept C203014093 @default.
- W2034995109 hasConcept C2775832221 @default.
- W2034995109 hasConcept C2778512257 @default.
- W2034995109 hasConcept C2778754761 @default.
- W2034995109 hasConcept C3019249092 @default.
- W2034995109 hasConcept C501593827 @default.
- W2034995109 hasConcept C547475151 @default.
- W2034995109 hasConcept C55493867 @default.
- W2034995109 hasConcept C57409179 @default.
- W2034995109 hasConcept C86803240 @default.
- W2034995109 hasConcept C89423630 @default.
- W2034995109 hasConceptScore W2034995109C104317684 @default.
- W2034995109 hasConceptScore W2034995109C153911025 @default.
- W2034995109 hasConceptScore W2034995109C185592680 @default.
- W2034995109 hasConceptScore W2034995109C202751555 @default.
- W2034995109 hasConceptScore W2034995109C203014093 @default.
- W2034995109 hasConceptScore W2034995109C2775832221 @default.
- W2034995109 hasConceptScore W2034995109C2778512257 @default.
- W2034995109 hasConceptScore W2034995109C2778754761 @default.
- W2034995109 hasConceptScore W2034995109C3019249092 @default.
- W2034995109 hasConceptScore W2034995109C501593827 @default.
- W2034995109 hasConceptScore W2034995109C547475151 @default.
- W2034995109 hasConceptScore W2034995109C55493867 @default.
- W2034995109 hasConceptScore W2034995109C57409179 @default.
- W2034995109 hasConceptScore W2034995109C86803240 @default.
- W2034995109 hasConceptScore W2034995109C89423630 @default.
- W2034995109 hasIssue "5" @default.
- W2034995109 hasLocation W20349951091 @default.
- W2034995109 hasLocation W20349951092 @default.
- W2034995109 hasOpenAccess W2034995109 @default.
- W2034995109 hasPrimaryLocation W20349951091 @default.
- W2034995109 hasRelatedWork W2019056229 @default.
- W2034995109 hasRelatedWork W2026176496 @default.
- W2034995109 hasRelatedWork W2050333345 @default.
- W2034995109 hasRelatedWork W2053138989 @default.
- W2034995109 hasRelatedWork W2101616908 @default.
- W2034995109 hasRelatedWork W2130181934 @default.
- W2034995109 hasRelatedWork W2806985130 @default.
- W2034995109 hasRelatedWork W2922081225 @default.
- W2034995109 hasRelatedWork W2963246688 @default.
- W2034995109 hasRelatedWork W57856700 @default.
- W2034995109 hasVolume "24" @default.
- W2034995109 isParatext "false" @default.
- W2034995109 isRetracted "false" @default.
- W2034995109 magId "2034995109" @default.
- W2034995109 workType "article" @default.