Matches in SemOpenAlex for { <https://semopenalex.org/work/W2034995887> ?p ?o ?g. }
- W2034995887 endingPage "185" @default.
- W2034995887 startingPage "179" @default.
- W2034995887 abstract "In view of the limited protection against tuberculosis, especially the infectious forms of pulmonary tuberculosis, afforded by Bacille Calmette-Guérin (BCG) vaccination, attempts are being made to develop more effective alternatives. Many of these attempts are based on the classical strategy of selecting ‘protective’ epitopes of Mycobacterium tuberculosis to induce immune responses in the vaccinated host. Such strategies, which in the past have been applied very effectively for the prevention of many acute infectious diseases, may not be relevant for a chronic disease in which both pathogen and host have co-evolved so that the majority of infected individuals remain asymptomatic, albeit latently infected, and in which inappropriate, dysregulated, patterns of immune reactivity predispose to, and maintain, the long-term pathological processes in a minority of symptomatic diseased individuals. While immune responses against the causative pathogen are of doubtless importance in the mediation of protection in the asymptomatic majority, we postulate that it is equally, or more, significant for public health to induce the required protective pattern of immune reactivity by immunotherapy in the diseased minority." @default.
- W2034995887 created "2016-06-24" @default.
- W2034995887 creator A5032122035 @default.
- W2034995887 creator A5063533861 @default.
- W2034995887 creator A5080925841 @default.
- W2034995887 date "2011-03-01" @default.
- W2034995887 modified "2023-09-23" @default.
- W2034995887 title "Immune protection against tuberculosis – When is immunotherapy preferable to vaccination?" @default.
- W2034995887 cites W1518628108 @default.
- W2034995887 cites W1546213590 @default.
- W2034995887 cites W1767934134 @default.
- W2034995887 cites W1839007275 @default.
- W2034995887 cites W1851903120 @default.
- W2034995887 cites W1853013744 @default.
- W2034995887 cites W1920434477 @default.
- W2034995887 cites W1938351738 @default.
- W2034995887 cites W1951330162 @default.
- W2034995887 cites W1973486503 @default.
- W2034995887 cites W1982662660 @default.
- W2034995887 cites W1984979380 @default.
- W2034995887 cites W1986743087 @default.
- W2034995887 cites W1989311055 @default.
- W2034995887 cites W1989960103 @default.
- W2034995887 cites W1994413997 @default.
- W2034995887 cites W1998980486 @default.
- W2034995887 cites W2020214471 @default.
- W2034995887 cites W2022706923 @default.
- W2034995887 cites W2024943377 @default.
- W2034995887 cites W2028938098 @default.
- W2034995887 cites W2050862002 @default.
- W2034995887 cites W2053336283 @default.
- W2034995887 cites W2053780295 @default.
- W2034995887 cites W2055648403 @default.
- W2034995887 cites W2061885139 @default.
- W2034995887 cites W2075477269 @default.
- W2034995887 cites W2080474739 @default.
- W2034995887 cites W2086083146 @default.
- W2034995887 cites W2089836547 @default.
- W2034995887 cites W2090680389 @default.
- W2034995887 cites W2097509788 @default.
- W2034995887 cites W2099016006 @default.
- W2034995887 cites W2100531445 @default.
- W2034995887 cites W2104122664 @default.
- W2034995887 cites W2104941073 @default.
- W2034995887 cites W2106395142 @default.
- W2034995887 cites W2106682613 @default.
- W2034995887 cites W2109543073 @default.
- W2034995887 cites W2112304840 @default.
- W2034995887 cites W2114104820 @default.
- W2034995887 cites W2119122291 @default.
- W2034995887 cites W2121626779 @default.
- W2034995887 cites W2124001620 @default.
- W2034995887 cites W2124123295 @default.
- W2034995887 cites W2125049374 @default.
- W2034995887 cites W2125737123 @default.
- W2034995887 cites W2133273161 @default.
- W2034995887 cites W2135423511 @default.
- W2034995887 cites W2142598100 @default.
- W2034995887 cites W2144870032 @default.
- W2034995887 cites W2155935320 @default.
- W2034995887 cites W2157559696 @default.
- W2034995887 cites W2157638040 @default.
- W2034995887 cites W2157918579 @default.
- W2034995887 cites W2171615504 @default.
- W2034995887 cites W2416903984 @default.
- W2034995887 cites W2496549934 @default.
- W2034995887 cites W4244007000 @default.
- W2034995887 cites W70165897 @default.
- W2034995887 cites W1966931926 @default.
- W2034995887 doi "https://doi.org/10.1016/j.tube.2010.12.004" @default.
- W2034995887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21233019" @default.
- W2034995887 hasPublicationYear "2011" @default.
- W2034995887 type Work @default.
- W2034995887 sameAs 2034995887 @default.
- W2034995887 citedByCount "18" @default.
- W2034995887 countsByYear W20349958872012 @default.
- W2034995887 countsByYear W20349958872013 @default.
- W2034995887 countsByYear W20349958872019 @default.
- W2034995887 countsByYear W20349958872021 @default.
- W2034995887 countsByYear W20349958872022 @default.
- W2034995887 countsByYear W20349958872023 @default.
- W2034995887 crossrefType "journal-article" @default.
- W2034995887 hasAuthorship W2034995887A5032122035 @default.
- W2034995887 hasAuthorship W2034995887A5063533861 @default.
- W2034995887 hasAuthorship W2034995887A5080925841 @default.
- W2034995887 hasConcept C142724271 @default.
- W2034995887 hasConcept C203014093 @default.
- W2034995887 hasConcept C22070199 @default.
- W2034995887 hasConcept C2776460866 @default.
- W2034995887 hasConcept C2777701055 @default.
- W2034995887 hasConcept C2777910003 @default.
- W2034995887 hasConcept C2777975735 @default.
- W2034995887 hasConcept C2779134260 @default.
- W2034995887 hasConcept C2781069245 @default.
- W2034995887 hasConcept C524204448 @default.
- W2034995887 hasConcept C71924100 @default.
- W2034995887 hasConcept C8891405 @default.
- W2034995887 hasConceptScore W2034995887C142724271 @default.