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- W2034997889 abstract "Injection of saralasin or converting-enzyme inhibitor produced a small variable reduction of blood-pressure in rats with two-kidney hypertension. Prolonged infusion of the inhibitors gradually reduced blood-pressure to normal. Control infusions of saralasin in normal animals and of dextrose in normal and hypertensive animals did not reduce blood-pressure. Plasma-renin concentration correlated significantly with the early but not with the later fall of blood-pressure. Plasma-concentrations of renin and angiotensin II were closely related except in rats receiving converting-enzyme inhibitor, when angiotensin II was relatively reduced. The gradual reduction of arterial pressure by saralasin was not associated with increased urinary sodium excretion." @default.
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- W2034997889 date "1977-12-01" @default.
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- W2034997889 title "CORRECTION OF RENAL HYPERTENSION IN THE RAT BY PROLONGED INFUSION OF ANGIOTENSIN INHIBITORS" @default.
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- W2034997889 doi "https://doi.org/10.1016/s0140-6736(77)90366-x" @default.
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