FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035006473> ?p ?o ?g. }

• W2035006473 endingPage "544" @default.
• W2035006473 startingPage "540" @default.
• W2035006473 abstract "Adipose tissue is a major, nonglandular site for the aromatization of androgens to estrogens. In this tissue, the aromatase activity resides primarily in the stromal cells, and we have used cultures of stromal cells to study the effects of insulin and insulin-like growth factor I (IGF-I) on aromatase activity. Adipose tissue, obtained during indicated surgery, was digested with collagenase, and the stromal cells were isolated and cultured. Aromatase activity was determined by measuring the tritiated water (3H2O) in the medium after incubating stromal cells with [1 beta-3H]androstenedione. Insulin and IGF-I had no effect on the aromatase activity in cultured adipose stromal cells at concentrations of 10 to 1,000 microU/ml. However, insulin (100 to 1,000 microU/ml) and IGF-I (500 ng/ml) markedly attenuated the stimulatory effect of (Bu)2cAMP, but significantly augmented the dexamethasone-stimulated aromatase activity. The greater effects of IGF-I compared with the effect of insulin are compatible with both effects being mediated through the IGF-I compared with the effect of insulin are compatible with both effects being mediated through the IGF-I receptor. In addition, the effects of insulin in attenuating the aromatase activity in adipose tissue could potentiate its role in hyperandrogenic syndromes in women." @default.
• W2035006473 created "2016-06-24" @default.
• W2035006473 creator A5001402501 @default.
• W2035006473 creator A5016898804 @default.
• W2035006473 creator A5083421561 @default.
• W2035006473 date "1990-12-01" @default.
• W2035006473 modified "2023-10-03" @default.
• W2035006473 title "Aromatase activity in human adipose tissue stromal cells: effect of growth factors" @default.
• W2035006473 cites W120069561 @default.
• W2035006473 cites W1775749144 @default.
• W2035006473 cites W1987557870 @default.
• W2035006473 cites W2000359588 @default.
• W2035006473 cites W2002196249 @default.
• W2035006473 cites W2013776505 @default.
• W2035006473 cites W2014183931 @default.
• W2035006473 cites W2047518704 @default.
• W2035006473 cites W2055659588 @default.
• W2035006473 cites W2068519706 @default.
• W2035006473 cites W2118703920 @default.
• W2035006473 cites W2124974256 @default.
• W2035006473 cites W2139448460 @default.
• W2035006473 cites W2160700601 @default.
• W2035006473 cites W2166434116 @default.
• W2035006473 doi "https://doi.org/10.1016/0039-128x(90)90049-h" @default.
• W2035006473 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1965238" @default.
• W2035006473 hasPublicationYear "1990" @default.
• W2035006473 type Work @default.
• W2035006473 sameAs 2035006473 @default.
• W2035006473 citedByCount "31" @default.
• W2035006473 countsByYear W20350064732013 @default.
• W2035006473 countsByYear W20350064732015 @default.
• W2035006473 countsByYear W20350064732016 @default.
• W2035006473 countsByYear W20350064732018 @default.
• W2035006473 countsByYear W20350064732019 @default.
• W2035006473 countsByYear W20350064732020 @default.
• W2035006473 countsByYear W20350064732022 @default.
• W2035006473 crossrefType "journal-article" @default.
• W2035006473 hasAuthorship W2035006473A5001402501 @default.
• W2035006473 hasAuthorship W2035006473A5016898804 @default.
• W2035006473 hasAuthorship W2035006473A5083421561 @default.
• W2035006473 hasConcept C121608353 @default.
• W2035006473 hasConcept C126322002 @default.
• W2035006473 hasConcept C134018914 @default.
• W2035006473 hasConcept C16930146 @default.
• W2035006473 hasConcept C170493617 @default.
• W2035006473 hasConcept C171089720 @default.
• W2035006473 hasConcept C181199279 @default.
• W2035006473 hasConcept C185592680 @default.
• W2035006473 hasConcept C2775960820 @default.
• W2035006473 hasConcept C2776166826 @default.
• W2035006473 hasConcept C2776683971 @default.
• W2035006473 hasConcept C2777911890 @default.
• W2035006473 hasConcept C2778394429 @default.
• W2035006473 hasConcept C2779306644 @default.
• W2035006473 hasConcept C2780689927 @default.
• W2035006473 hasConcept C530470458 @default.
• W2035006473 hasConcept C55493867 @default.
• W2035006473 hasConcept C71315377 @default.
• W2035006473 hasConcept C71924100 @default.
• W2035006473 hasConcept C86803240 @default.
• W2035006473 hasConceptScore W2035006473C121608353 @default.
• W2035006473 hasConceptScore W2035006473C126322002 @default.
• W2035006473 hasConceptScore W2035006473C134018914 @default.
• W2035006473 hasConceptScore W2035006473C16930146 @default.
• W2035006473 hasConceptScore W2035006473C170493617 @default.
• W2035006473 hasConceptScore W2035006473C171089720 @default.
• W2035006473 hasConceptScore W2035006473C181199279 @default.
• W2035006473 hasConceptScore W2035006473C185592680 @default.
• W2035006473 hasConceptScore W2035006473C2775960820 @default.
• W2035006473 hasConceptScore W2035006473C2776166826 @default.
• W2035006473 hasConceptScore W2035006473C2776683971 @default.
• W2035006473 hasConceptScore W2035006473C2777911890 @default.
• W2035006473 hasConceptScore W2035006473C2778394429 @default.
• W2035006473 hasConceptScore W2035006473C2779306644 @default.
• W2035006473 hasConceptScore W2035006473C2780689927 @default.
• W2035006473 hasConceptScore W2035006473C530470458 @default.
• W2035006473 hasConceptScore W2035006473C55493867 @default.
• W2035006473 hasConceptScore W2035006473C71315377 @default.
• W2035006473 hasConceptScore W2035006473C71924100 @default.
• W2035006473 hasConceptScore W2035006473C86803240 @default.
• W2035006473 hasIssue "12" @default.
• W2035006473 hasLocation W20350064731 @default.
• W2035006473 hasLocation W20350064732 @default.
• W2035006473 hasOpenAccess W2035006473 @default.
• W2035006473 hasPrimaryLocation W20350064731 @default.
• W2035006473 hasRelatedWork W1975650642 @default.
• W2035006473 hasRelatedWork W1989449228 @default.
• W2035006473 hasRelatedWork W2019149333 @default.
• W2035006473 hasRelatedWork W2024629959 @default.
• W2035006473 hasRelatedWork W2033535765 @default.
• W2035006473 hasRelatedWork W2035006473 @default.
• W2035006473 hasRelatedWork W2046364739 @default.
• W2035006473 hasRelatedWork W2051039150 @default.
• W2035006473 hasRelatedWork W2089385669 @default.
• W2035006473 hasRelatedWork W2163000286 @default.
• W2035006473 hasVolume "55" @default.
• W2035006473 isParatext "false" @default.
• W2035006473 isRetracted "false" @default.

• next