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- W2035008903 abstract "We report a case of de novo myelodysplastic syndrome (MDS) with hypereosinophilia and dic(1;7) in which eosinophil clonal involvement was confirmed by fluorescence in situ hybridization. There have been two previous reports in the literature of eosinophilic MDS with dic(1;7) or t(1;7) in which eosinophil clonality was demonstrated. The specific breakpoints on chromosomes 1 and 7 differ in the three cases, making it difficult to implicate disruption of a single gene as causative; nevertheless, the nonrandom occurrence of t(1;7) or dic(1;7) with malignant eosinophilic proliferations suggests that this chromosomal rearrangement is involved in the etiology of the disease." @default.
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- W2035008903 date "1998-11-01" @default.
- W2035008903 modified "2023-09-27" @default.
- W2035008903 title "Myelodysplastic Syndrome with Hypereosinophilia and a Nonrandom Chromosomal Abnormality dic(1;7)" @default.
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- W2035008903 doi "https://doi.org/10.1016/s0165-4608(98)00055-7" @default.
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