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- W2035039308 abstract "The antigenic properties of cross-linked proteins were examined. Cross-linking was performed by coupling proteins to the diazonium groups of a mixed polycondensate of aromatic amino carboxylic acids. The resulting cross-linked protein samples were soluble under physiological conditions. The immunogenic capacity was determined without the use of adjuvants by intravenous injection. The cross-linked proteins have been found to give a greatly enhanced antibody response compared with the original proteins. The antisera obtained after immunization with cross-linked proteins cross-reacted with the original protein monomers (kallikrein inactivator, ribonuclease, human chorionic gonadotropin) and neutralized their biological activity." @default.
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- W2035039308 date "1969-01-01" @default.
- W2035039308 modified "2023-09-23" @default.
- W2035039308 title "Antigenic properties of proteins cross-linked by multidiazonium compounds" @default.
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- W2035039308 doi "https://doi.org/10.1016/0019-2791(69)90173-6" @default.
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