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- W2035044277 abstract "Prostate cancer survivors with advanced disease are commonly treated with androgen deprivation therapy (ADT). Serious side effects of ADT are rapid bone and muscle loss and fat gain that can compromise physical fitness and function. PURPOSE: We present preliminary data from an on-going randomized controlled one-year trial of strength training (STR) versus a control program of flexibility training (FLEX) in prostate cancer survivors on ADT. METHODS: To date, we have 20 men who have completed 6 months of exercise, baseline and 6 month testing (STR n=12 and FLEX n=8). Selected measures include the following: upper and lower body strength by 1-repetition maximum bench press (BPmax) and leg press (LPmax), functional leg and arm strength by time to complete 5 chair stands (CStime) and grip strength (GRP); and physical function by the physical performance battery (PPB). Paired t-tests were used to evaluate within group differences and ANOVA were used to compare differences between groups over time. RESULTS: There were no differences at baseline between groups in age, weight, height and physical function (p>.05). At 6 months, between group comparisons show that STR significantly increased BPmax (p=0.01) and a trend for improvement in CStime (p=.08) compared to FLEX. From baseline to 6 months, STR improved BPmax (p=.02) and CStime (p=.01) while the FLEX group decreased in GRP (p=.005) (Table 1).Table 1: % change in physical fitness and physical function measures after 6 months of trainingCONCLUSION: These preliminary data suggest that six months of strength training increases upper and lower body strength in men on ADT for prostate cancer. Definitive conclusions are precluded until the trial is complete. Supported by the Lance Armstrong Foundation" @default.
- W2035044277 created "2016-06-24" @default.
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- W2035044277 date "2008-05-01" @default.
- W2035044277 modified "2023-09-26" @default.
- W2035044277 title "Randomized, Controlled Trial of Resistance Exercise in Prostate Cancer Survivors on ADT: Preliminary Findings" @default.
- W2035044277 doi "https://doi.org/10.1249/01.mss.0000321939.74721.fa" @default.
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