FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035045356> ?p ?o ?g. }

• W2035045356 endingPage "548" @default.
• W2035045356 startingPage "545" @default.
• W2035045356 abstract "Background The current study investigates circulating eosinophils and neutrophils in Alzheimer′s (AD) type dementia with respect to density (kg/L). The existence of β-amyloid plaques in the brain is a feature of AD. Sporadic scientific reports indicate that the disease affects circulating neutrophils. In contrast, numerous publications investigate inflammatory reactions in AD brains. Locally, the plaques evoke a substantial inflammatory response involving activated microglia and astrocytes. Methods Subjects with probable AD (n = 39) were included and compared with elderly individuals (n = 22) lacking apparent memory problems. We sampled 10 mL venous blood in citrate. Granulocytes were separated according to density in linear Percoll™ gradients. Subsequently, the gradients were divided into density subfractions (n = 16). In every fraction, determination of eosinophil and neutrophil counts was carried out. Results AD sufferers displayed less granulocytes in fractions nos. 13-15 containing light cells. For these fractions, the P-values proved to be (P < 0·001; not significant; P = 0·03) and (P = 0·01; P = 0·01; not significant), for eosinophils and neutrophils, respectively. Conclusions The present work describes that less circulating light granulocytes are a feature of AD demented individuals. It is to hypothesize that it is a sign of impaired granulocyte turnover and cell damage. It is concluded that AD affects inflammatory cells in the periphery and that the behaviour of granulocytes in dementia is worthwhile further studies." @default.
• W2035045356 created "2016-06-24" @default.
• W2035045356 creator A5023142366 @default.
• W2035045356 creator A5025965154 @default.
• W2035045356 creator A5059023883 @default.
• W2035045356 creator A5072195521 @default.
• W2035045356 creator A5077832898 @default.
• W2035045356 date "2013-03-29" @default.
• W2035045356 modified "2023-10-17" @default.
• W2035045356 title "Alzheimer′s disease and granulocyte density diversity" @default.
• W2035045356 cites W1489837340 @default.
• W2035045356 cites W1598703170 @default.
• W2035045356 cites W1607927168 @default.
• W2035045356 cites W1991375558 @default.
• W2035045356 cites W2003114525 @default.
• W2035045356 cites W2007591654 @default.
• W2035045356 cites W2008584995 @default.
• W2035045356 cites W2012215271 @default.
• W2035045356 cites W2022719538 @default.
• W2035045356 cites W2047932752 @default.
• W2035045356 cites W2079670332 @default.
• W2035045356 cites W2120968206 @default.
• W2035045356 cites W2126660834 @default.
• W2035045356 cites W2141363596 @default.
• W2035045356 cites W2156013098 @default.
• W2035045356 cites W2165703295 @default.
• W2035045356 cites W2261144307 @default.
• W2035045356 doi "https://doi.org/10.1111/eci.12072" @default.
• W2035045356 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23551244" @default.
• W2035045356 hasPublicationYear "2013" @default.
• W2035045356 type Work @default.
• W2035045356 sameAs 2035045356 @default.
• W2035045356 citedByCount "13" @default.
• W2035045356 countsByYear W20350453562014 @default.
• W2035045356 countsByYear W20350453562015 @default.
• W2035045356 countsByYear W20350453562016 @default.
• W2035045356 countsByYear W20350453562017 @default.
• W2035045356 countsByYear W20350453562019 @default.
• W2035045356 countsByYear W20350453562020 @default.
• W2035045356 countsByYear W20350453562021 @default.
• W2035045356 countsByYear W20350453562022 @default.
• W2035045356 countsByYear W20350453562023 @default.
• W2035045356 crossrefType "journal-article" @default.
• W2035045356 hasAuthorship W2035045356A5023142366 @default.
• W2035045356 hasAuthorship W2035045356A5025965154 @default.
• W2035045356 hasAuthorship W2035045356A5059023883 @default.
• W2035045356 hasAuthorship W2035045356A5072195521 @default.
• W2035045356 hasAuthorship W2035045356A5077832898 @default.
• W2035045356 hasBestOaLocation W20350453562 @default.
• W2035045356 hasConcept C142724271 @default.
• W2035045356 hasConcept C203014093 @default.
• W2035045356 hasConcept C2776042228 @default.
• W2035045356 hasConcept C2776914184 @default.
• W2035045356 hasConcept C2777037409 @default.
• W2035045356 hasConcept C2777983669 @default.
• W2035045356 hasConcept C2779134260 @default.
• W2035045356 hasConcept C2779483572 @default.
• W2035045356 hasConcept C2779830541 @default.
• W2035045356 hasConcept C48679268 @default.
• W2035045356 hasConcept C502032728 @default.
• W2035045356 hasConcept C55493867 @default.
• W2035045356 hasConcept C71924100 @default.
• W2035045356 hasConcept C7623868 @default.
• W2035045356 hasConcept C86803240 @default.
• W2035045356 hasConceptScore W2035045356C142724271 @default.
• W2035045356 hasConceptScore W2035045356C203014093 @default.
• W2035045356 hasConceptScore W2035045356C2776042228 @default.
• W2035045356 hasConceptScore W2035045356C2776914184 @default.
• W2035045356 hasConceptScore W2035045356C2777037409 @default.
• W2035045356 hasConceptScore W2035045356C2777983669 @default.
• W2035045356 hasConceptScore W2035045356C2779134260 @default.
• W2035045356 hasConceptScore W2035045356C2779483572 @default.
• W2035045356 hasConceptScore W2035045356C2779830541 @default.
• W2035045356 hasConceptScore W2035045356C48679268 @default.
• W2035045356 hasConceptScore W2035045356C502032728 @default.
• W2035045356 hasConceptScore W2035045356C55493867 @default.
• W2035045356 hasConceptScore W2035045356C71924100 @default.
• W2035045356 hasConceptScore W2035045356C7623868 @default.
• W2035045356 hasConceptScore W2035045356C86803240 @default.
• W2035045356 hasIssue "6" @default.
• W2035045356 hasLocation W20350453561 @default.
• W2035045356 hasLocation W20350453562 @default.
• W2035045356 hasLocation W20350453563 @default.
• W2035045356 hasOpenAccess W2035045356 @default.
• W2035045356 hasPrimaryLocation W20350453561 @default.
• W2035045356 hasRelatedWork W1968132178 @default.
• W2035045356 hasRelatedWork W2035045356 @default.
• W2035045356 hasRelatedWork W2089190654 @default.
• W2035045356 hasRelatedWork W2094353975 @default.
• W2035045356 hasRelatedWork W2139189445 @default.
• W2035045356 hasRelatedWork W2467076809 @default.
• W2035045356 hasRelatedWork W2990530825 @default.
• W2035045356 hasRelatedWork W313460363 @default.
• W2035045356 hasRelatedWork W4249661632 @default.
• W2035045356 hasRelatedWork W4255249625 @default.
• W2035045356 hasVolume "43" @default.
• W2035045356 isParatext "false" @default.
• W2035045356 isRetracted "false" @default.

• next