Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035084050> ?p ?o ?g. }
- W2035084050 endingPage "1725" @default.
- W2035084050 startingPage "1717" @default.
- W2035084050 abstract "Olig2 is a recently identified transcription factor involved in the phenotype definition of cells in the oligodendroglial lineage. The expression of Olig2 transcript has been demonstrated in human oligodendroglial tumors, although the protein expression has not been studied extensively. We developed a polyclonal antibody to human Olig2 and analyzed it immunohistochemically. The antibody depicted a single distinct band of predicted molecular weight by Western blotting, and did not cross-react with human Olig1. In normal human brain tissue, the nuclei of oligodendrocytes of interfascicular, perivascular, and perineuronal disposition were clearly labeled by the antibody. Similarly, the nuclei of oligodendroglial tumors were labeled. There was no apparent correlation between the staining intensity and histological grade. Astrocytic components within the tumors were generally less or not stained. Astrocytic tumors were also positive with the Olig2 antiserum to a lesser extent, and the difference between oligodendroglial and astrocytic tumors was demonstrated by a statistical analysis. Olig2 and glial fibrillary acidic protein were expressed in a mutually exclusive manner, and Olig2 expression was cell-cycle related. Neither central neurocytoma nor schwannoma cases were stained. Our antibody was demonstrated to be useful in recognizing normal oligodendrocytes on paraffin sections, and applicable in diagnosis of some brain tumors." @default.
- W2035084050 created "2016-06-24" @default.
- W2035084050 creator A5022941572 @default.
- W2035084050 creator A5039588385 @default.
- W2035084050 creator A5047625485 @default.
- W2035084050 creator A5051624965 @default.
- W2035084050 creator A5054509094 @default.
- W2035084050 creator A5054653023 @default.
- W2035084050 creator A5070873966 @default.
- W2035084050 creator A5074587065 @default.
- W2035084050 creator A5075869021 @default.
- W2035084050 date "2004-05-01" @default.
- W2035084050 modified "2023-09-27" @default.
- W2035084050 title "Anti-Human Olig2 Antibody as a Useful Immunohistochemical Marker of Normal Oligodendrocytes and Gliomas" @default.
- W2035084050 cites W151561789 @default.
- W2035084050 cites W1878193927 @default.
- W2035084050 cites W1958675029 @default.
- W2035084050 cites W1970734161 @default.
- W2035084050 cites W1975203903 @default.
- W2035084050 cites W1982449679 @default.
- W2035084050 cites W2012768021 @default.
- W2035084050 cites W2018289835 @default.
- W2035084050 cites W2036568272 @default.
- W2035084050 cites W2040141693 @default.
- W2035084050 cites W2045998998 @default.
- W2035084050 cites W2046288500 @default.
- W2035084050 cites W2048162805 @default.
- W2035084050 cites W2049856211 @default.
- W2035084050 cites W2058850778 @default.
- W2035084050 cites W2069059931 @default.
- W2035084050 cites W2071508056 @default.
- W2035084050 cites W2080490176 @default.
- W2035084050 cites W2082178034 @default.
- W2035084050 cites W2085185944 @default.
- W2035084050 cites W2085188825 @default.
- W2035084050 cites W2099882112 @default.
- W2035084050 cites W2100837269 @default.
- W2035084050 cites W2105574313 @default.
- W2035084050 cites W2117720558 @default.
- W2035084050 cites W2128464557 @default.
- W2035084050 cites W2129605816 @default.
- W2035084050 cites W2133036212 @default.
- W2035084050 cites W2133437679 @default.
- W2035084050 cites W2139144917 @default.
- W2035084050 cites W2151617172 @default.
- W2035084050 cites W2307117515 @default.
- W2035084050 cites W2414564539 @default.
- W2035084050 cites W2417808079 @default.
- W2035084050 cites W37630318 @default.
- W2035084050 doi "https://doi.org/10.1016/s0002-9440(10)63730-3" @default.
- W2035084050 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1615653" @default.
- W2035084050 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15111318" @default.
- W2035084050 hasPublicationYear "2004" @default.
- W2035084050 type Work @default.
- W2035084050 sameAs 2035084050 @default.
- W2035084050 citedByCount "125" @default.
- W2035084050 countsByYear W20350840502012 @default.
- W2035084050 countsByYear W20350840502013 @default.
- W2035084050 countsByYear W20350840502014 @default.
- W2035084050 countsByYear W20350840502015 @default.
- W2035084050 countsByYear W20350840502016 @default.
- W2035084050 countsByYear W20350840502017 @default.
- W2035084050 countsByYear W20350840502018 @default.
- W2035084050 countsByYear W20350840502019 @default.
- W2035084050 countsByYear W20350840502020 @default.
- W2035084050 countsByYear W20350840502021 @default.
- W2035084050 countsByYear W20350840502022 @default.
- W2035084050 countsByYear W20350840502023 @default.
- W2035084050 crossrefType "journal-article" @default.
- W2035084050 hasAuthorship W2035084050A5022941572 @default.
- W2035084050 hasAuthorship W2035084050A5039588385 @default.
- W2035084050 hasAuthorship W2035084050A5047625485 @default.
- W2035084050 hasAuthorship W2035084050A5051624965 @default.
- W2035084050 hasAuthorship W2035084050A5054509094 @default.
- W2035084050 hasAuthorship W2035084050A5054653023 @default.
- W2035084050 hasAuthorship W2035084050A5070873966 @default.
- W2035084050 hasAuthorship W2035084050A5074587065 @default.
- W2035084050 hasAuthorship W2035084050A5075869021 @default.
- W2035084050 hasBestOaLocation W20350840502 @default.
- W2035084050 hasConcept C134018914 @default.
- W2035084050 hasConcept C142724271 @default.
- W2035084050 hasConcept C159654299 @default.
- W2035084050 hasConcept C169760540 @default.
- W2035084050 hasConcept C203014093 @default.
- W2035084050 hasConcept C204232928 @default.
- W2035084050 hasConcept C2776985911 @default.
- W2035084050 hasConcept C2777670902 @default.
- W2035084050 hasConcept C2777931997 @default.
- W2035084050 hasConcept C2778227246 @default.
- W2035084050 hasConcept C2778609137 @default.
- W2035084050 hasConcept C2778880634 @default.
- W2035084050 hasConcept C2779055221 @default.
- W2035084050 hasConcept C2780495277 @default.
- W2035084050 hasConcept C2910969760 @default.
- W2035084050 hasConcept C35866371 @default.
- W2035084050 hasConcept C502942594 @default.
- W2035084050 hasConcept C529278444 @default.
- W2035084050 hasConcept C71924100 @default.