FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035106144> ?p ?o ?g. }

• W2035106144 endingPage "16969" @default.
• W2035106144 startingPage "16966" @default.
• W2035106144 abstract "By a targeted enzyme engineering approach, we were able to create an efficient NADPH oxidase from a monooxygenase. Intriguingly, replacement of only one specific single amino acid was sufficient for such a monooxygenase-to-oxidase switch-a complete transition in enzyme activity. Pre-steady-state kinetic analysis and elucidation of the crystal structure of the C65D PAMO mutant revealed that the mutation introduces small changes near the flavin cofactor, resulting in a rapid decay of the peroxyflavin intermediate. The engineered biocatalyst was shown to be a thermostable, solvent tolerant, and effective cofactor-regenerating biocatalyst. Therefore, it represents a valuable new biocatalytic tool." @default.
• W2035106144 created "2016-06-24" @default.
• W2035106144 creator A5014709239 @default.
• W2035106144 creator A5014727680 @default.
• W2035106144 creator A5017449175 @default.
• W2035106144 creator A5064149441 @default.
• W2035106144 creator A5083203989 @default.
• W2035106144 date "2014-12-01" @default.
• W2035106144 modified "2023-10-18" @default.
• W2035106144 title "Finding the Switch: Turning a Baeyer–Villiger Monooxygenase into a NADPH Oxidase" @default.
• W2035106144 cites W1985987885 @default.
• W2035106144 cites W1991856308 @default.
• W2035106144 cites W2003195256 @default.
• W2035106144 cites W2016742544 @default.
• W2035106144 cites W2017035524 @default.
• W2035106144 cites W2025006941 @default.
• W2035106144 cites W2036549565 @default.
• W2035106144 cites W2045104784 @default.
• W2035106144 cites W2049229059 @default.
• W2035106144 cites W2057929337 @default.
• W2035106144 cites W2063968116 @default.
• W2035106144 cites W2069764626 @default.
• W2035106144 cites W2076167006 @default.
• W2035106144 cites W2077388906 @default.
• W2035106144 cites W2084087974 @default.
• W2035106144 cites W2085697507 @default.
• W2035106144 cites W2102619095 @default.
• W2035106144 cites W2106812423 @default.
• W2035106144 cites W2111275962 @default.
• W2035106144 cites W2127456273 @default.
• W2035106144 cites W2143980500 @default.
• W2035106144 cites W2155205527 @default.
• W2035106144 cites W2163845215 @default.
• W2035106144 cites W2166196545 @default.
• W2035106144 cites W2322436721 @default.
• W2035106144 cites W4254813422 @default.
• W2035106144 doi "https://doi.org/10.1021/ja508265b" @default.
• W2035106144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25423359" @default.
• W2035106144 hasPublicationYear "2014" @default.
• W2035106144 type Work @default.
• W2035106144 sameAs 2035106144 @default.
• W2035106144 citedByCount "41" @default.
• W2035106144 countsByYear W20351061442015 @default.
• W2035106144 countsByYear W20351061442016 @default.
• W2035106144 countsByYear W20351061442017 @default.
• W2035106144 countsByYear W20351061442018 @default.
• W2035106144 countsByYear W20351061442019 @default.
• W2035106144 countsByYear W20351061442020 @default.
• W2035106144 countsByYear W20351061442021 @default.
• W2035106144 countsByYear W20351061442022 @default.
• W2035106144 countsByYear W20351061442023 @default.
• W2035106144 crossrefType "journal-article" @default.
• W2035106144 hasAuthorship W2035106144A5014709239 @default.
• W2035106144 hasAuthorship W2035106144A5014727680 @default.
• W2035106144 hasAuthorship W2035106144A5017449175 @default.
• W2035106144 hasAuthorship W2035106144A5064149441 @default.
• W2035106144 hasAuthorship W2035106144A5083203989 @default.
• W2035106144 hasConcept C104317684 @default.
• W2035106144 hasConcept C13002179 @default.
• W2035106144 hasConcept C143065580 @default.
• W2035106144 hasConcept C147816474 @default.
• W2035106144 hasConcept C161790260 @default.
• W2035106144 hasConcept C181199279 @default.
• W2035106144 hasConcept C185592680 @default.
• W2035106144 hasConcept C191503008 @default.
• W2035106144 hasConcept C197957613 @default.
• W2035106144 hasConcept C21951064 @default.
• W2035106144 hasConcept C2776146729 @default.
• W2035106144 hasConcept C33093398 @default.
• W2035106144 hasConcept C38485361 @default.
• W2035106144 hasConcept C526171541 @default.
• W2035106144 hasConcept C55493867 @default.
• W2035106144 hasConcept C65024703 @default.
• W2035106144 hasConcept C71240020 @default.
• W2035106144 hasConcept C9418097 @default.
• W2035106144 hasConceptScore W2035106144C104317684 @default.
• W2035106144 hasConceptScore W2035106144C13002179 @default.
• W2035106144 hasConceptScore W2035106144C143065580 @default.
• W2035106144 hasConceptScore W2035106144C147816474 @default.
• W2035106144 hasConceptScore W2035106144C161790260 @default.
• W2035106144 hasConceptScore W2035106144C181199279 @default.
• W2035106144 hasConceptScore W2035106144C185592680 @default.
• W2035106144 hasConceptScore W2035106144C191503008 @default.
• W2035106144 hasConceptScore W2035106144C197957613 @default.
• W2035106144 hasConceptScore W2035106144C21951064 @default.
• W2035106144 hasConceptScore W2035106144C2776146729 @default.
• W2035106144 hasConceptScore W2035106144C33093398 @default.
• W2035106144 hasConceptScore W2035106144C38485361 @default.
• W2035106144 hasConceptScore W2035106144C526171541 @default.
• W2035106144 hasConceptScore W2035106144C55493867 @default.
• W2035106144 hasConceptScore W2035106144C65024703 @default.
• W2035106144 hasConceptScore W2035106144C71240020 @default.
• W2035106144 hasConceptScore W2035106144C9418097 @default.
• W2035106144 hasFunder F4320320300 @default.
• W2035106144 hasFunder F4320322025 @default.
• W2035106144 hasIssue "49" @default.
• W2035106144 hasLocation W20351061441 @default.
• W2035106144 hasLocation W20351061442 @default.

• next