Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035135964> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2035135964 endingPage "40" @default.
- W2035135964 startingPage "33" @default.
- W2035135964 abstract "Previous in vivo and in vitro studies have reported a variety of glucocorticoid effects on the synthesis and secretion of immunoreactive atrial natriuretic peptide (ir-ANP) into plasma. To further define glucocorticoid modulation of ir-ANP, we have measured ir-ANP levels in plasma and the four cardiac chambers, and tissue ANP mRNA levels, in intact rats and adrenalectomized rats with or without dexamethasone treatment for 1, 2, 4, 8 and 16 days. Plasma levels fell by 50% between 8 and 16 days post-adrenalectomy; in contrast, dexamethasone treatment caused a 3-fold rise in plasma ANP 1-2 days post-adrenalectomy, with levels gradually returning to control by day 16. Circulating forms of ANP were unchanged by adrenalectomy or dexamethasone treatment, as were atrial ANP concentrations and ANP mRNA levels. Left ventricular ANP concentrations rose with dexamethasone treatment, and ventricular ANP mRNA levels changed in parallel with those of circulating ANP. The in vivo effect of glucocorticoids (at moderate rather than very high doses) on ANP synthesis and secretion thus appears to be predominantly but not exclusively upon the left ventricle rather than the atria." @default.
- W2035135964 created "2016-06-24" @default.
- W2035135964 creator A5021676408 @default.
- W2035135964 creator A5051067965 @default.
- W2035135964 creator A5053353813 @default.
- W2035135964 date "1991-11-01" @default.
- W2035135964 modified "2023-09-27" @default.
- W2035135964 title "Adrenalectomy and dexamethasone administration: effect on atrial natriuretic peptide synthesis and circulating forms" @default.
- W2035135964 cites W1513376682 @default.
- W2035135964 cites W1527988096 @default.
- W2035135964 cites W1589980560 @default.
- W2035135964 cites W1963921468 @default.
- W2035135964 cites W1971482865 @default.
- W2035135964 cites W1998961225 @default.
- W2035135964 cites W2004564179 @default.
- W2035135964 cites W2006590911 @default.
- W2035135964 cites W2011873189 @default.
- W2035135964 cites W2027433465 @default.
- W2035135964 cites W2039109285 @default.
- W2035135964 cites W2050097502 @default.
- W2035135964 cites W2060333964 @default.
- W2035135964 cites W2080068550 @default.
- W2035135964 cites W2081629353 @default.
- W2035135964 cites W2083322514 @default.
- W2035135964 cites W2085864418 @default.
- W2035135964 cites W2116278557 @default.
- W2035135964 cites W2309664819 @default.
- W2035135964 cites W2408765981 @default.
- W2035135964 doi "https://doi.org/10.1016/0303-7207(91)90006-e" @default.
- W2035135964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1837001" @default.
- W2035135964 hasPublicationYear "1991" @default.
- W2035135964 type Work @default.
- W2035135964 sameAs 2035135964 @default.
- W2035135964 citedByCount "17" @default.
- W2035135964 countsByYear W20351359642013 @default.
- W2035135964 countsByYear W20351359642016 @default.
- W2035135964 countsByYear W20351359642022 @default.
- W2035135964 crossrefType "journal-article" @default.
- W2035135964 hasAuthorship W2035135964A5021676408 @default.
- W2035135964 hasAuthorship W2035135964A5051067965 @default.
- W2035135964 hasAuthorship W2035135964A5053353813 @default.
- W2035135964 hasConcept C126322002 @default.
- W2035135964 hasConcept C134018914 @default.
- W2035135964 hasConcept C150903083 @default.
- W2035135964 hasConcept C185592680 @default.
- W2035135964 hasConcept C207001950 @default.
- W2035135964 hasConcept C2778069365 @default.
- W2035135964 hasConcept C2778921608 @default.
- W2035135964 hasConcept C2780087391 @default.
- W2035135964 hasConcept C2780401358 @default.
- W2035135964 hasConcept C2780841215 @default.
- W2035135964 hasConcept C56191518 @default.
- W2035135964 hasConcept C71315377 @default.
- W2035135964 hasConcept C71924100 @default.
- W2035135964 hasConcept C86803240 @default.
- W2035135964 hasConceptScore W2035135964C126322002 @default.
- W2035135964 hasConceptScore W2035135964C134018914 @default.
- W2035135964 hasConceptScore W2035135964C150903083 @default.
- W2035135964 hasConceptScore W2035135964C185592680 @default.
- W2035135964 hasConceptScore W2035135964C207001950 @default.
- W2035135964 hasConceptScore W2035135964C2778069365 @default.
- W2035135964 hasConceptScore W2035135964C2778921608 @default.
- W2035135964 hasConceptScore W2035135964C2780087391 @default.
- W2035135964 hasConceptScore W2035135964C2780401358 @default.
- W2035135964 hasConceptScore W2035135964C2780841215 @default.
- W2035135964 hasConceptScore W2035135964C56191518 @default.
- W2035135964 hasConceptScore W2035135964C71315377 @default.
- W2035135964 hasConceptScore W2035135964C71924100 @default.
- W2035135964 hasConceptScore W2035135964C86803240 @default.
- W2035135964 hasIssue "1" @default.
- W2035135964 hasLocation W20351359641 @default.
- W2035135964 hasLocation W20351359642 @default.
- W2035135964 hasOpenAccess W2035135964 @default.
- W2035135964 hasPrimaryLocation W20351359641 @default.
- W2035135964 hasRelatedWork W1536622731 @default.
- W2035135964 hasRelatedWork W1970091690 @default.
- W2035135964 hasRelatedWork W1976035881 @default.
- W2035135964 hasRelatedWork W2023696391 @default.
- W2035135964 hasRelatedWork W2071337848 @default.
- W2035135964 hasRelatedWork W2076884793 @default.
- W2035135964 hasRelatedWork W2080960184 @default.
- W2035135964 hasRelatedWork W2171633312 @default.
- W2035135964 hasRelatedWork W2276893008 @default.
- W2035135964 hasRelatedWork W2319230747 @default.
- W2035135964 hasVolume "82" @default.
- W2035135964 isParatext "false" @default.
- W2035135964 isRetracted "false" @default.
- W2035135964 magId "2035135964" @default.
- W2035135964 workType "article" @default.