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- W2035150549 abstract "Slit-scan flow cytometry provides a method to analyze large numbers of metaphase chromosomes in a relatively short time due to morphological features. The high detection rate requires fast computing for on-line analysis. Up to now, this has been achieved using special-purpose computers, parallel systems or other complex hardware. Here, we describe an algorithm that can be implemented on a general-purpose personal computer. Digitized chromosome profiles can be classified by several criteria especially for the detection of chromosome abnormalities in biological dosimetry. A data set of approximately 4600 profiles was used. Programming in assembler results in an average computing time of about 600 microseconds per profile. Thus on-line evaluation of slit-scanning data appears to become feasible for many flow cytometers running nowadays." @default.
- W2035150549 created "2016-06-24" @default.
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- W2035150549 date "1993-01-01" @default.
- W2035150549 modified "2023-10-16" @default.
- W2035150549 title "Time-optimized analysis of slit-scan chromosome profiles on a general-purpose personal computer" @default.
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- W2035150549 doi "https://doi.org/10.1093/bioinformatics/9.4.381" @default.
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