FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035168735> ?p ?o ?g. }

• W2035168735 endingPage "1502" @default.
• W2035168735 startingPage "1497" @default.
• W2035168735 abstract "CYP2C19 is a cytochrome P450 enzyme, which is involved in the metabolism of some clinically important medications and is encoded by a highly polymorphic gene. There is no available data on the distribution of the CYP2C19 *4 and *17 mutant alleles in the Saudi Arabian population. The aim of the study was to determine different CYP2C19 mutant allele (*2, *4 and *17) frequencies in healthy Saudi subjects and to determine genotype frequencies for these mutations. The CYP2C19 genotypes were then classified into phenotypes.In 201 adults of Saudi ethnicity, the allele frequencies were CYP2C19*1 (62.9%), *17 (25.7%), *2 (11.2%) and *4 (0.2%). The most prevalent genotype combinations were CYP2C19 *1/*1 (40.3%) and *1/*17 (30.4%). The distribution of CYP2C19 phenotypes was divided into extensive metabolizers (EM) 77.6%, intermediate metabolizers (IM) 14.9%, ultra-rapid metabolizers (UM) 7% and poor metabolizers (PM) 0.4%. This finding has important clinical implications for the use of CYP2C19 metabolized medications in the Saudi population and further studies are needed." @default.
• W2035168735 created "2016-06-24" @default.
• W2035168735 creator A5041779818 @default.
• W2035168735 creator A5047859899 @default.
• W2035168735 date "2013-01-01" @default.
• W2035168735 modified "2023-10-01" @default.
• W2035168735 title "Genotype-Phenotype Analysis of CYP2C19 in Healthy Saudi Individuals and its Potential Clinical Implication in Drug Therapy" @default.
• W2035168735 cites W1502407336 @default.
• W2035168735 cites W1599071048 @default.
• W2035168735 cites W1924733673 @default.
• W2035168735 cites W1963784624 @default.
• W2035168735 cites W1967274335 @default.
• W2035168735 cites W1969825491 @default.
• W2035168735 cites W1979157261 @default.
• W2035168735 cites W1981612922 @default.
• W2035168735 cites W1985059672 @default.
• W2035168735 cites W1985798331 @default.
• W2035168735 cites W1986064902 @default.
• W2035168735 cites W1991886667 @default.
• W2035168735 cites W1992477076 @default.
• W2035168735 cites W1994334380 @default.
• W2035168735 cites W1995765358 @default.
• W2035168735 cites W2001141842 @default.
• W2035168735 cites W2017294431 @default.
• W2035168735 cites W2018197611 @default.
• W2035168735 cites W2019482344 @default.
• W2035168735 cites W2021241943 @default.
• W2035168735 cites W2023475370 @default.
• W2035168735 cites W2037641376 @default.
• W2035168735 cites W2037711001 @default.
• W2035168735 cites W2057037588 @default.
• W2035168735 cites W2062727128 @default.
• W2035168735 cites W2068804178 @default.
• W2035168735 cites W2073557728 @default.
• W2035168735 cites W2075200277 @default.
• W2035168735 cites W2077824949 @default.
• W2035168735 cites W2081558811 @default.
• W2035168735 cites W2086439537 @default.
• W2035168735 cites W2087691066 @default.
• W2035168735 cites W2090307434 @default.
• W2035168735 cites W2094199640 @default.
• W2035168735 cites W2095199926 @default.
• W2035168735 cites W2096399169 @default.
• W2035168735 cites W2108825946 @default.
• W2035168735 cites W2131633795 @default.
• W2035168735 cites W2149774429 @default.
• W2035168735 cites W2158406175 @default.
• W2035168735 cites W2159858918 @default.
• W2035168735 cites W2159940312 @default.
• W2035168735 cites W2164923007 @default.
• W2035168735 cites W2170125927 @default.
• W2035168735 cites W2171085701 @default.
• W2035168735 cites W2185337991 @default.
• W2035168735 cites W2332796264 @default.
• W2035168735 doi "https://doi.org/10.7150/ijms.6795" @default.
• W2035168735 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3775106" @default.
• W2035168735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24046523" @default.
• W2035168735 hasPublicationYear "2013" @default.
• W2035168735 type Work @default.
• W2035168735 sameAs 2035168735 @default.
• W2035168735 citedByCount "29" @default.
• W2035168735 countsByYear W20351687352014 @default.
• W2035168735 countsByYear W20351687352015 @default.
• W2035168735 countsByYear W20351687352016 @default.
• W2035168735 countsByYear W20351687352017 @default.
• W2035168735 countsByYear W20351687352018 @default.
• W2035168735 countsByYear W20351687352019 @default.
• W2035168735 countsByYear W20351687352020 @default.
• W2035168735 countsByYear W20351687352021 @default.
• W2035168735 countsByYear W20351687352022 @default.
• W2035168735 countsByYear W20351687352023 @default.
• W2035168735 crossrefType "journal-article" @default.
• W2035168735 hasAuthorship W2035168735A5041779818 @default.
• W2035168735 hasAuthorship W2035168735A5047859899 @default.
• W2035168735 hasBestOaLocation W20351687351 @default.
• W2035168735 hasConcept C104317684 @default.
• W2035168735 hasConcept C126322002 @default.
• W2035168735 hasConcept C127716648 @default.
• W2035168735 hasConcept C135763542 @default.
• W2035168735 hasConcept C140840227 @default.
• W2035168735 hasConcept C180754005 @default.
• W2035168735 hasConcept C2780035454 @default.
• W2035168735 hasConcept C2908647359 @default.
• W2035168735 hasConcept C37463918 @default.
• W2035168735 hasConcept C54355233 @default.
• W2035168735 hasConcept C55775858 @default.
• W2035168735 hasConcept C71924100 @default.
• W2035168735 hasConcept C86803240 @default.
• W2035168735 hasConcept C98274493 @default.
• W2035168735 hasConcept C99454951 @default.
• W2035168735 hasConceptScore W2035168735C104317684 @default.
• W2035168735 hasConceptScore W2035168735C126322002 @default.
• W2035168735 hasConceptScore W2035168735C127716648 @default.
• W2035168735 hasConceptScore W2035168735C135763542 @default.
• W2035168735 hasConceptScore W2035168735C140840227 @default.
• W2035168735 hasConceptScore W2035168735C180754005 @default.
• W2035168735 hasConceptScore W2035168735C2780035454 @default.
• W2035168735 hasConceptScore W2035168735C2908647359 @default.

• next