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- W2035241112 endingPage "383" @default.
- W2035241112 startingPage "369" @default.
- W2035241112 abstract "The charge state distribution of proteins was studied as a function of experimental conditions, to improve the understanding of the matrix-assisted laser desorption/ionization (MALDI) mechanisms. The relative abundances of the multiply-charged ions appear to be a function of the matrix chosen, the laser fluence and the matrix-to-analyte molar ratio. A correlation is found between the matrix proton affinity and the yield of singly- versus multiply-charged ions. These results are in good agreement with a model in which gas-phase intracluster reactions play a significant role in analyte ion formation. A new model for endothermic desolvation processes in ultraviolet/MALDI is presented and discussed. It is based upon the existence of highly-charged precursor clusters and, complementary to the ion survivor model of Karas et al., assumes that two energy-dependent processes exist: (i) a soft desolvation involving consecutive losses of neutral matrix molecules, leading to a multiply-charged analyte and (ii) hard desolvation leading to a low charge state analyte, by consecutive losses of charged matrix molecules. These desolvations pathways are discussed in terms of kinetically limited processes. The efficiency of the two competitive desolvation processes seems related to the internal energy carried away by clusters during ablation." @default.
- W2035241112 created "2016-06-24" @default.
- W2035241112 creator A5035375779 @default.
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- W2035241112 creator A5089155546 @default.
- W2035241112 creator A5089340124 @default.
- W2035241112 creator A5091272930 @default.
- W2035241112 date "2006-12-01" @default.
- W2035241112 modified "2023-10-11" @default.
- W2035241112 title "Gas-Phase Ionization/Desolvation Processes and Their Effect on Protein Charge State Distribution under Matrix-Assisted Laser Desorption/Ionization Conditions" @default.
- W2035241112 cites W1969385917 @default.
- W2035241112 cites W1970737141 @default.
- W2035241112 cites W1971477276 @default.
- W2035241112 cites W1972926169 @default.
- W2035241112 cites W1973163422 @default.
- W2035241112 cites W1976434493 @default.
- W2035241112 cites W1977122050 @default.
- W2035241112 cites W1977634165 @default.
- W2035241112 cites W1978504388 @default.
- W2035241112 cites W1978528584 @default.
- W2035241112 cites W1978659737 @default.
- W2035241112 cites W1979136141 @default.
- W2035241112 cites W1979494925 @default.
- W2035241112 cites W1979550529 @default.
- W2035241112 cites W1984733035 @default.
- W2035241112 cites W1984844544 @default.
- W2035241112 cites W1986693684 @default.
- W2035241112 cites W1988152381 @default.
- W2035241112 cites W1991004491 @default.
- W2035241112 cites W1991829241 @default.
- W2035241112 cites W1993191718 @default.
- W2035241112 cites W1994103130 @default.
- W2035241112 cites W1994984489 @default.
- W2035241112 cites W1996076449 @default.
- W2035241112 cites W1996849028 @default.
- W2035241112 cites W2000125682 @default.
- W2035241112 cites W2000447465 @default.
- W2035241112 cites W2010780595 @default.
- W2035241112 cites W2012715914 @default.
- W2035241112 cites W2013281794 @default.
- W2035241112 cites W2013317909 @default.
- W2035241112 cites W2016092523 @default.
- W2035241112 cites W2017107873 @default.
- W2035241112 cites W2021807280 @default.
- W2035241112 cites W2021840092 @default.
- W2035241112 cites W2022286379 @default.
- W2035241112 cites W2022335990 @default.
- W2035241112 cites W2022354632 @default.
- W2035241112 cites W2022381933 @default.
- W2035241112 cites W2022962522 @default.
- W2035241112 cites W2023171189 @default.
- W2035241112 cites W2026617703 @default.
- W2035241112 cites W2028175491 @default.
- W2035241112 cites W2028318922 @default.
- W2035241112 cites W2032706303 @default.
- W2035241112 cites W2032974966 @default.
- W2035241112 cites W2034484994 @default.
- W2035241112 cites W2034639888 @default.
- W2035241112 cites W2037430355 @default.
- W2035241112 cites W2039026185 @default.
- W2035241112 cites W2042096537 @default.
- W2035241112 cites W2044039308 @default.
- W2035241112 cites W2044092698 @default.
- W2035241112 cites W2045265557 @default.
- W2035241112 cites W2046424545 @default.
- W2035241112 cites W2046592165 @default.
- W2035241112 cites W2047940872 @default.
- W2035241112 cites W2048418998 @default.
- W2035241112 cites W2053837941 @default.
- W2035241112 cites W2055954673 @default.
- W2035241112 cites W2058113162 @default.
- W2035241112 cites W2062317131 @default.
- W2035241112 cites W2062704587 @default.
- W2035241112 cites W2062752098 @default.
- W2035241112 cites W2063062533 @default.
- W2035241112 cites W2069818999 @default.
- W2035241112 cites W2070753507 @default.
- W2035241112 cites W2071143650 @default.
- W2035241112 cites W2072258521 @default.
- W2035241112 cites W2072809800 @default.
- W2035241112 cites W2076426164 @default.
- W2035241112 cites W2080371313 @default.
- W2035241112 cites W2081310223 @default.
- W2035241112 cites W2081598183 @default.
- W2035241112 cites W2082152811 @default.
- W2035241112 cites W2084231943 @default.
- W2035241112 cites W2088442796 @default.
- W2035241112 cites W2089117569 @default.
- W2035241112 cites W2090673085 @default.
- W2035241112 cites W2092094702 @default.
- W2035241112 cites W2092105992 @default.
- W2035241112 cites W2092143116 @default.
- W2035241112 cites W2094245123 @default.
- W2035241112 cites W2096932401 @default.
- W2035241112 cites W2098315720 @default.
- W2035241112 cites W2099245439 @default.
- W2035241112 cites W2100105524 @default.
- W2035241112 cites W2100152083 @default.