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- W2035282018 endingPage "433" @default.
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- W2035282018 abstract "Abundant tau-positive neurofibrillary lesions constitute a defining neuropathological characteristic of Alzheimer's disease. Filamentous tau pathology is also central to a number of other dementing disorders, such as Pick's disease, progressive supranuclear palsy, corticobasal degeneration and familial frontotemporal dementia and Parkinsonism linked to chromosome 17 (FTDP-17). The discovery of mutations in the tau gene in FTDP-17 has firmly established the relevance of tau pathology for the neurodegenerative process. Experimental studies have provided a system for the assembly of full-length tau into Alzheimer-like filaments, providing an assay for the testing of compounds that inhabit the formation of tau filaments." @default.
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- W2035282018 date "1998-10-01" @default.
- W2035282018 modified "2023-10-18" @default.
- W2035282018 title "Tau protein pathology in neurodegenerative diseases" @default.
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- W2035282018 doi "https://doi.org/10.1016/s0166-2236(98)01337-x" @default.
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