Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035293987> ?p ?o ?g. }
- W2035293987 endingPage "629" @default.
- W2035293987 startingPage "622" @default.
- W2035293987 abstract "In immunocompromised renal transplant patients, aspergillosis can be a life-threatening opportunistic infection. During an 8-year period, 25 renal transplant recipients at the University of Minnesota Hospitals developed unequivocal invasive aspergillosis that occurred in epidemic-like patterns in immunocompromised patients throughout the hospital. The premortem diagnosis was made in only 14 of the 25 patients. Seventeen patients died, and three of the eight survivors lost their allografts. The prognosis was dependent upon the clinical pattern of illness: three clinical patterns emerged: (1) cavitary lung disease, (2) diffuse pulmonary disease, and (3) central nervous system disease. All patients in the latter two categories died. The best results were with those patients treated with both amphotericin B and excision of cavitary lung lesions. All three patients treated in this manner survived with functioning grafts. Traditionally, sputum cultures have been thought to be unreliable because Aspergillus is a common colonizer of the upper respiratory tract and a contaminant in laboratories. In this study, false positive sputum cultures were common. A positive sputum culture can be helpful, however, all patients with two positive sputum cultures proved to have invasive aspergillosis. In addition, 86% of patients with positive sputum cultures who were clinically ill proved to have invasive infection. Bronchoscopy is a useful technique to follow up a positive sputum culture or investigate negative sputum cultures with typical clinical patterns. Routine bronchoscopy, unfortunately, also yields a high incidence of false positive cultures. Since the use of covered brush bronchoscopy technique, however, no false positive transbronchial cultures have been found. Transbronchial biopsy is a useful adjunct and is proof of the presence of invasive disease when the results are positive. However, false negative results are also found. Overall, the highest diagnostic yield is obtained both with transbronchial lung biopsy and covered brush bronchoscopy culture. All eight patients with both these procedures were correctly identified as having invasive pulmonary aspergillosis." @default.
- W2035293987 created "2016-06-24" @default.
- W2035293987 creator A5022646943 @default.
- W2035293987 creator A5023092705 @default.
- W2035293987 creator A5060532902 @default.
- W2035293987 creator A5061747256 @default.
- W2035293987 creator A5072822768 @default.
- W2035293987 creator A5079726745 @default.
- W2035293987 date "1983-11-01" @default.
- W2035293987 modified "2023-09-25" @default.
- W2035293987 title "Aspergillosis in 25 Renal Transplant Patients" @default.
- W2035293987 cites W123024795 @default.
- W2035293987 cites W1791083430 @default.
- W2035293987 cites W1869163352 @default.
- W2035293987 cites W1970785533 @default.
- W2035293987 cites W1972792163 @default.
- W2035293987 cites W1996152805 @default.
- W2035293987 cites W2002080923 @default.
- W2035293987 cites W2014245517 @default.
- W2035293987 cites W2039720197 @default.
- W2035293987 cites W2043795282 @default.
- W2035293987 cites W2049291162 @default.
- W2035293987 cites W2049619483 @default.
- W2035293987 cites W2055681392 @default.
- W2035293987 cites W2062217860 @default.
- W2035293987 cites W2087467642 @default.
- W2035293987 cites W2092722218 @default.
- W2035293987 cites W2105420440 @default.
- W2035293987 cites W2223776750 @default.
- W2035293987 cites W2253773124 @default.
- W2035293987 cites W2404956079 @default.
- W2035293987 cites W2416658325 @default.
- W2035293987 cites W4255187335 @default.
- W2035293987 doi "https://doi.org/10.1097/00000658-198311000-00011" @default.
- W2035293987 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1353135" @default.
- W2035293987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6357114" @default.
- W2035293987 hasPublicationYear "1983" @default.
- W2035293987 type Work @default.
- W2035293987 sameAs 2035293987 @default.
- W2035293987 citedByCount "139" @default.
- W2035293987 countsByYear W20352939872012 @default.
- W2035293987 countsByYear W20352939872013 @default.
- W2035293987 countsByYear W20352939872014 @default.
- W2035293987 countsByYear W20352939872015 @default.
- W2035293987 countsByYear W20352939872016 @default.
- W2035293987 countsByYear W20352939872017 @default.
- W2035293987 countsByYear W20352939872018 @default.
- W2035293987 countsByYear W20352939872019 @default.
- W2035293987 countsByYear W20352939872021 @default.
- W2035293987 countsByYear W20352939872023 @default.
- W2035293987 crossrefType "journal-article" @default.
- W2035293987 hasAuthorship W2035293987A5022646943 @default.
- W2035293987 hasAuthorship W2035293987A5023092705 @default.
- W2035293987 hasAuthorship W2035293987A5060532902 @default.
- W2035293987 hasAuthorship W2035293987A5061747256 @default.
- W2035293987 hasAuthorship W2035293987A5072822768 @default.
- W2035293987 hasAuthorship W2035293987A5079726745 @default.
- W2035293987 hasBestOaLocation W20352939872 @default.
- W2035293987 hasConcept C120665830 @default.
- W2035293987 hasConcept C121332964 @default.
- W2035293987 hasConcept C126322002 @default.
- W2035293987 hasConcept C141071460 @default.
- W2035293987 hasConcept C142724271 @default.
- W2035293987 hasConcept C203014093 @default.
- W2035293987 hasConcept C2776301714 @default.
- W2035293987 hasConcept C2776391196 @default.
- W2035293987 hasConcept C2778996910 @default.
- W2035293987 hasConcept C2779912665 @default.
- W2035293987 hasConcept C2781069245 @default.
- W2035293987 hasConcept C2781448352 @default.
- W2035293987 hasConcept C2911091166 @default.
- W2035293987 hasConcept C61511704 @default.
- W2035293987 hasConcept C71924100 @default.
- W2035293987 hasConceptScore W2035293987C120665830 @default.
- W2035293987 hasConceptScore W2035293987C121332964 @default.
- W2035293987 hasConceptScore W2035293987C126322002 @default.
- W2035293987 hasConceptScore W2035293987C141071460 @default.
- W2035293987 hasConceptScore W2035293987C142724271 @default.
- W2035293987 hasConceptScore W2035293987C203014093 @default.
- W2035293987 hasConceptScore W2035293987C2776301714 @default.
- W2035293987 hasConceptScore W2035293987C2776391196 @default.
- W2035293987 hasConceptScore W2035293987C2778996910 @default.
- W2035293987 hasConceptScore W2035293987C2779912665 @default.
- W2035293987 hasConceptScore W2035293987C2781069245 @default.
- W2035293987 hasConceptScore W2035293987C2781448352 @default.
- W2035293987 hasConceptScore W2035293987C2911091166 @default.
- W2035293987 hasConceptScore W2035293987C61511704 @default.
- W2035293987 hasConceptScore W2035293987C71924100 @default.
- W2035293987 hasIssue "5" @default.
- W2035293987 hasLocation W20352939871 @default.
- W2035293987 hasLocation W20352939872 @default.
- W2035293987 hasLocation W20352939873 @default.
- W2035293987 hasOpenAccess W2035293987 @default.
- W2035293987 hasPrimaryLocation W20352939871 @default.
- W2035293987 hasRelatedWork W1966614608 @default.
- W2035293987 hasRelatedWork W1980359814 @default.
- W2035293987 hasRelatedWork W2034138099 @default.
- W2035293987 hasRelatedWork W2035293987 @default.