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• W2035295169 abstract "The mechanisms regulating mitochondrial outer-membrane permeabilization and the release of cytochrome c during apoptosis remain controversial. In the present study, we show in an in vitro model system that the release of cytochrome c may occur via moderate modulation of mitochondrial volume, irrespective of the mechanism leading to the mitochondrial swelling. In contrast with mitochondrial permeability transition-dependent release of cytochrome c, in the present study mitochondria remain intact and functionally active." @default.
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• W2035295169 date "2004-02-15" @default.
• W2035295169 modified "2023-09-30" @default.
• W2035295169 title "Mitochondrial cytochrome c release may occur by volume-dependent mechanisms not involving permeability transition" @default.
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• W2035295169 doi "https://doi.org/10.1042/bj20031193" @default.
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