FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2035323144> ?p ?o ?g. }

• W2035323144 endingPage "e56435" @default.
• W2035323144 startingPage "e56435" @default.
• W2035323144 abstract "Individualized approaches to prognosis are crucial to effective management of cancer patients. We developed a methodology to assign individualized 5-year disease-specific death probabilities to 1,222 patients with melanoma and to 1,225 patients with breast cancer. For each cancer, three risk subgroups were identified by stratifying patients according to initial stage, and prediction probabilities were generated based on the factors most closely related to 5-year disease-specific death. Separate subgroup probabilities were merged to form a single composite index, and its predictive efficacy was assessed by several measures, including the area (AUC) under its receiver operating characteristic (ROC) curve. The patient-centered methodology achieved an AUC of 0.867 in the prediction of 5-year disease-specific death, compared with 0.787 using the AJCC staging classification alone. When applied to breast cancer patients, it achieved an AUC of 0.907, compared with 0.802 using the AJCC staging classification alone. A prognostic algorithm produced from a randomly selected training subsample of 800 melanoma patients preserved 92.5% of its prognostic efficacy (as measured by AUC) when the same algorithm was applied to a validation subsample containing the remaining patients. Finally, the tailored prognostic approach enhanced the identification of high-risk candidates for adjuvant therapy in melanoma. These results describe a novel patient-centered prognostic methodology with improved predictive efficacy when compared with AJCC stage alone in two distinct malignancies drawn from two separate populations." @default.
• W2035323144 created "2016-06-24" @default.
• W2035323144 creator A5011501753 @default.
• W2035323144 creator A5066416832 @default.
• W2035323144 creator A5079717318 @default.
• W2035323144 creator A5090618504 @default.
• W2035323144 date "2013-02-27" @default.
• W2035323144 modified "2023-09-27" @default.
• W2035323144 title "A Patient-Centered Methodology That Improves the Accuracy of Prognostic Predictions in Cancer" @default.
• W2035323144 cites W1828940258 @default.
• W2035323144 cites W1908752382 @default.
• W2035323144 cites W1951046932 @default.
• W2035323144 cites W1967611979 @default.
• W2035323144 cites W1987424755 @default.
• W2035323144 cites W2013840898 @default.
• W2035323144 cites W2025316386 @default.
• W2035323144 cites W2027163111 @default.
• W2035323144 cites W2048912425 @default.
• W2035323144 cites W2068283389 @default.
• W2035323144 cites W2081422533 @default.
• W2035323144 cites W2081984856 @default.
• W2035323144 cites W2092342071 @default.
• W2035323144 cites W2097001550 @default.
• W2035323144 cites W2098076634 @default.
• W2035323144 cites W2100083473 @default.
• W2035323144 cites W2101347382 @default.
• W2035323144 cites W2110457899 @default.
• W2035323144 cites W2112316706 @default.
• W2035323144 cites W2118449798 @default.
• W2035323144 cites W2118863192 @default.
• W2035323144 cites W2131365547 @default.
• W2035323144 cites W2142844057 @default.
• W2035323144 cites W2146549124 @default.
• W2035323144 cites W4240458912 @default.
• W2035323144 doi "https://doi.org/10.1371/journal.pone.0056435" @default.
• W2035323144 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3584071" @default.
• W2035323144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23460802" @default.
• W2035323144 hasPublicationYear "2013" @default.
• W2035323144 type Work @default.
• W2035323144 sameAs 2035323144 @default.
• W2035323144 citedByCount "5" @default.
• W2035323144 countsByYear W20353231442013 @default.
• W2035323144 countsByYear W20353231442016 @default.
• W2035323144 countsByYear W20353231442018 @default.
• W2035323144 countsByYear W20353231442020 @default.
• W2035323144 countsByYear W20353231442023 @default.
• W2035323144 crossrefType "journal-article" @default.
• W2035323144 hasAuthorship W2035323144A5011501753 @default.
• W2035323144 hasAuthorship W2035323144A5066416832 @default.
• W2035323144 hasAuthorship W2035323144A5079717318 @default.
• W2035323144 hasAuthorship W2035323144A5090618504 @default.
• W2035323144 hasBestOaLocation W20353231441 @default.
• W2035323144 hasConcept C121608353 @default.
• W2035323144 hasConcept C126322002 @default.
• W2035323144 hasConcept C143998085 @default.
• W2035323144 hasConcept C146357865 @default.
• W2035323144 hasConcept C151730666 @default.
• W2035323144 hasConcept C2777658100 @default.
• W2035323144 hasConcept C2777982462 @default.
• W2035323144 hasConcept C2779134260 @default.
• W2035323144 hasConcept C2780325254 @default.
• W2035323144 hasConcept C502942594 @default.
• W2035323144 hasConcept C530470458 @default.
• W2035323144 hasConcept C58471807 @default.
• W2035323144 hasConcept C71924100 @default.
• W2035323144 hasConcept C76318530 @default.
• W2035323144 hasConcept C86803240 @default.
• W2035323144 hasConceptScore W2035323144C121608353 @default.
• W2035323144 hasConceptScore W2035323144C126322002 @default.
• W2035323144 hasConceptScore W2035323144C143998085 @default.
• W2035323144 hasConceptScore W2035323144C146357865 @default.
• W2035323144 hasConceptScore W2035323144C151730666 @default.
• W2035323144 hasConceptScore W2035323144C2777658100 @default.
• W2035323144 hasConceptScore W2035323144C2777982462 @default.
• W2035323144 hasConceptScore W2035323144C2779134260 @default.
• W2035323144 hasConceptScore W2035323144C2780325254 @default.
• W2035323144 hasConceptScore W2035323144C502942594 @default.
• W2035323144 hasConceptScore W2035323144C530470458 @default.
• W2035323144 hasConceptScore W2035323144C58471807 @default.
• W2035323144 hasConceptScore W2035323144C71924100 @default.
• W2035323144 hasConceptScore W2035323144C76318530 @default.
• W2035323144 hasConceptScore W2035323144C86803240 @default.
• W2035323144 hasIssue "2" @default.
• W2035323144 hasLocation W20353231441 @default.
• W2035323144 hasLocation W20353231442 @default.
• W2035323144 hasLocation W20353231443 @default.
• W2035323144 hasLocation W20353231444 @default.
• W2035323144 hasLocation W20353231445 @default.
• W2035323144 hasLocation W20353231446 @default.
• W2035323144 hasOpenAccess W2035323144 @default.
• W2035323144 hasPrimaryLocation W20353231441 @default.
• W2035323144 hasRelatedWork W2000536166 @default.
• W2035323144 hasRelatedWork W2026425527 @default.
• W2035323144 hasRelatedWork W2079161020 @default.
• W2035323144 hasRelatedWork W2172254302 @default.
• W2035323144 hasRelatedWork W2224319365 @default.
• W2035323144 hasRelatedWork W2263577673 @default.
• W2035323144 hasRelatedWork W2405001942 @default.

• next